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The objective of this study is to describe the frequency and the clinical, paraclinical, and treatment profile of patients with lupus psychosis in a Colombian cohort of patients with systemic lupus erythematosus (SLE). This retrospective cohort study evaluated epidemiological and clinical characteristics, results of neuroimaging, analysis of the cerebrospinal fluid, treatment, and disease evolution in patients with lupus psychosis. Among 2,479 patients with SLE, six female patients aged between 20 and 50 years with a diagnosis of lupus psychosis were identified. In two patients, psychosis was present at disease onset and in the other four, SLE was already present, although the majority of them were diagnosed less than two years prior to the onset of psychosis. The entire cohort had high disease activity as measured by SLEDAI-2K. We found concomitant cutaneous, joint, and hematological alterations. Cerebrospinal fluid data were obtained in half of the patients and were normal. We performed brain tomography on most of our patients, which was almost always described as normal. In 5 out of 6 patients, the induction therapy to treat psychosis was based on steroids, and in the majority of them, a resolution of psychiatric symptoms was observed after initiating treatment. Lupus psychosis is a rare event that usually occurs early in the course of the disease and is associated with other manifestations of SLE. This investigation mainly found concomitant cutaneous, joint, and hematological manifestations, with a favorable outcome after treatment, as described in the literature.

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This paper analyses the effect of High-Performance Work Systems (HPWS) and Total Quality Management (TQM) on business performance. An extensive literature review made it possible to establish four hypotheses, along with a comprehensive path model of relationships tested by means of structural equation modelling (SEM) using the partial least squares (PLS) technique. The results show that HPWS positively influence business performance and TQM which, in return, directly improves business performance and mediates in the HPWS-business performance relationship. Upon considering these conclusions, we can, therefore, state that the integration of both human resource management and total quality management is a key strategy for a company.

La conciencia fenoménica es la propiedad que los estados, sucesos y procesos mentales poseen cuando, y sólo cuando, hay algo que es como algo para el sujeto que los posee; para experimentarlos o estar en tales estados. Hay algo que es como oler café recién preparado. Tener la experiencia de oler café recién preparado es un estado fenoménicamente conciente. Comúnmente, qué es algo como tener una experiencia conciente refiere al carácter fenoménico de las experiencias. Las teorías de la conciencia intentan explicar éste carácter fenoménico.