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Your search keyword '"Injections, Intraventricular"' showing total 14 results
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14 results on '"Injections, Intraventricular"'

1. [Co-involvement of catecholaminergic and gabaergic transmission in the electro-cortical response to central galanin administration in the rabbit].

Author

Maurelli M, Marchioni E, and Tartara A

Subjects
Animals, Baclofen pharmacology, Catecholamines antagonists & inhibitors, Ditiocarb pharmacology, Drug Interactions, GABA Antagonists, Galanin, Injections, Intraventricular, Methyltyrosines pharmacology, Muscimol pharmacology, Peptides administration & dosage, Rabbits, alpha-Methyltyrosine, Catecholamines physiology, Electroencephalography drug effects, Peptides pharmacology, Synaptic Transmission drug effects, gamma-Aminobutyric Acid physiology
Abstract

The involvement of catecholaminergic and gabaergic transmission in the electrocortical pattern induced by centrally administered galanin was investigated in the rabbit. The inhibition of catecholamine synthesis by both DDC and alphaMPT potentiated the EEG effect of the peptide. Baclofen and muscimol significantly enhanced the EEG response to GAL. However the interaction between the peptide and gabaergic transmission seemed mainly to involve the type A receptor system.

Published
1993

2. [EEG and autonomic effects of centrally administered galanin in the rabbit].

Author

Maurelli M, Marchioni E, and Tartara A

Subjects
Animals, Behavior, Animal drug effects, Body Temperature drug effects, Electrocardiography drug effects, Galanin, Injections, Intraventricular, Peptides administration & dosage, Rabbits, Respiration drug effects, Autonomic Nervous System drug effects, Electroencephalography drug effects, Hypnotics and Sedatives pharmacology, Peptides pharmacology
Abstract

The effects of centrally administered galanin (10 and 20 mcg) on the EEG, somatic behaviour and some autonomic parameters have been studied in unanesthetized rabbits. In this species the peptide induced a dose related increase in electrocortical power spectrum density and behavioural sedation. Autonomic changes, consisting in moderate hyperthermia and bradypnea, were seen only after the highest dose of the peptide. These data support a central action of the peptide and suggest a role for galanin as sedative neuropeptide.

Published
1993

5. [Effect of cathionine (alpha-aminopropiophenone) on rat EEG activity]

Author

Berardelli A, Capocaccia L, Deodati M, VIRGINIA TANCREDI, Quinteri F, and As, Elmi

Subjects
Male, Amphetamine, Chemistry, Propiophenones, Alkaloids, Chemical Phenomena, Dose-Response Relationship, Drug, Seizures, Animals, Brain, Electroencephalography, Injections, Intraventricular, Rats
Abstract

We have studied the effect induced by the injection of Cathinone (alpha-aminopropiophenone) into the cerebral ventricle. This substance has recently been isolated from the leaves of the Catha Edulis. The chemical structure of Cathinone is similar to that of amphetamine. However, Cathinone does not modify cerebral electric activity in sense of a typical activation seen with amphetamine. Cathinone has evoked, at high doses, seizures comparable to epileptic activity.

Published
1980

6. [Effects of dimaprit, an H2 receptor agonist, on blood levels of corticosterone in the rat].

Author

Basile V, Amoroso S, and Di Renzo GF

Subjects
Animals, Dimaprit, Injections, Intraperitoneal, Injections, Intraventricular, Male, Rats, Rats, Inbred Strains, Thiourea administration & dosage, Corticosterone blood, Receptors, Histamine metabolism, Receptors, Histamine H2 metabolism, Thiourea pharmacology
Abstract

These experiments were performed in order to further clarify the role played by hystamine in the control of hypothalamus-hypophisis-adrenal axis. To this aim we evaluated the effect of Dimaprit, a H2 agonist on plasma corticosterone levels. This drug was administered intraperitoneally or i.c.v. at the doses of 25, 50 and 100 mg/kg or 100 gamma/animal respectively. The administration i.p. at the dose of 100 mg/kg increased plasma-corticosterone levels whereas Dimaprit, injected intraventricularly did not modify plasma-corticosterone levels. These results seem to suggest that Dimaprit stimulates corticosterone secretion at a peripheral level.

Published
1983

7. [Cerebral ventriculitis in childhood].

Author

Agabiti N, Caldarelli M, Di Rocco C, Marietti G, and Paone FM

Subjects
Anti-Bacterial Agents therapeutic use, Cerebrospinal Fluid Shunts, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Injections, Intraventricular, Male, Peritoneum, Anti-Bacterial Agents administration & dosage, Bacterial Infections drug therapy, Cerebral Ventricles, Encephalitis drug therapy
Published
1988

8. [Effect of TRH and anti-TRH serum in experimental ulcerogenesis in the rat].

Author

Bagarani M, Genco A, Polito M, Verde B, Rabino R, Materia A, and Munari C

Subjects
Animals, Cold Temperature adverse effects, Injections, Intraventricular, Male, Rats, Rats, Inbred Strains, Thyrotropin-Releasing Hormone antagonists & inhibitors, Immune Sera pharmacology, Stomach Ulcer chemically induced, Thyrotropin-Releasing Hormone adverse effects
Published
1986

9. [ACTH and eating behavior].

Author

Vergoni AV, Poggioli R, Vaccina F, and Bertolini A

Subjects
Animals, Brain drug effects, Cosyntropin administration & dosage, Injections, Intraventricular, Male, Rats, Rats, Inbred Strains, Cosyntropin pharmacology, Feeding Behavior drug effects
Published
1988

11. [Epidural and intraventricular morphine therapy in the treatment of cancer pain].

Author

Caputi CA, Busca G, Fogliardi A, Rychlicki F, and Basili P

Subjects
Adult, Aged, Aged, 80 and over, Epidural Space, Female, Humans, Injections, Injections, Intraventricular, Male, Middle Aged, Morphine administration & dosage, Pain, Intractable etiology, Morphine therapeutic use, Neoplasms physiopathology, Pain, Intractable drug therapy
Published
1986

12. [Time course analysis of the effects of intrapeduncular injection of kainic acid on amygdaloid paroxysmal activity].

Author

Crescimanno G, Benigno A, and Raieli V

Subjects
Animals, Cats, Decerebrate State, Injections, Intraventricular, Kainic Acid pharmacology, Mesencephalon, Time Factors, Kainic Acid administration & dosage, Pyrrolidines administration & dosage
Abstract

Intrapeduncolar intrapeduncolar entopeduncolar injection of kainic acid determines an early decrease of the evoked amygdaloid paroxysmal activity, and a later increase of the AD length. The diphasic effect of the injection of kainic acid into the entopeduncular nucleus is likely due to the structural analogy of this drug with a neuroexcitant amino acid, monosodium glutamate. The inhibitory role of the entopeduncolar nucleus on the paroxysmal phenomena evoked in the amygdala is emphasized.

Published
1982

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