1. [Long-term survival of patients with inoperable hepatocarcinoma, treated with interventional radiology].
- Author
-
Rossi P, Maccioni F, Iacobelli D, Rossi M, Broglia L, Bezzi M, and Iacari V
- Subjects
- Actuarial Analysis, Adult, Aged, Antibiotics, Antineoplastic administration & dosage, Chemoembolization, Therapeutic methods, Combined Modality Therapy, Epirubicin administration & dosage, Female, Follow-Up Studies, Humans, Iodized Oil administration & dosage, Liver Neoplasms diagnostic imaging, Male, Middle Aged, Palliative Care, Tomography, X-Ray Computed, Carcinoma, Hepatocellular diagnostic imaging, Carcinoma, Hepatocellular mortality, Liver Neoplasms mortality, Liver Neoplasms therapy, Radiography, Interventional methods
- Abstract
Survival rates in untreated patients with unresectable HCC are rather disappointing. Our study was aimed at assessing long-term survival in the patients submitted to combined transarterial chemoembolization (TACE) and percutaneous ethanol injection (PEI). We treated 223 patients, but long-term follow-up is available in 143 of them only. Eighty-seven of 143 patients had Child's A liver cirrhosis, 45 had Child's B and 6 Child's C. Five patients did not have cirrhosis. Eighty-seven patients had single lesions--45 of them < 5 cm and 42 > 5 cm. Fifty-six patients had multiple/diffuse lesions. All patients underwent TACE while PEI was performed in selected patients with single or double lesions. Survival rates were calculated with the life-table analysis by Kaplan and Meyer. Follow-up was 1-72 months (median: 28 months). At 1, 3 and 5 years, the overall survival rates were 72%, 34.5% and 16.4%, respectively. The survival rates at 1, 3 and 5 years in single lesions < 5 cm were 90.4%, 52.1% and 34.8%, respectively, vs. 69.4%, 37.4% and 18.7% in lesions > 5 cm and 58.8%, 12.5% and 0% in multiple/diffuse lesions. In conclusion, the long-term results of the radiologic treatment of unresectable HCC are comparable with surgical results obtained in selected cases.
- Published
- 1995