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Start Over Descriptor "Chromosomal Proteins, Non-Histone metabolism" Language italian
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3. [Chromosomal proteins: histones and acid proteins].

Author

Salvini M and Gabrielli F

Subjects
Acetylation, Amino Acid Sequence, Animals, Chemical Phenomena, Chemistry, Chromatin, Chromosomal Proteins, Non-Histone metabolism, DNA biosynthesis, Embryo, Mammalian metabolism, Embryo, Nonmammalian, Histones biosynthesis, Histones metabolism, Lysine analysis, Meiosis, Methylation, Oogenesis, Oxidation-Reduction, Phosphorylation, Protein Biosynthesis, RNA biosynthesis, Species Specificity, Sulfhydryl Compounds metabolism, Chromosomal Proteins, Non-Histone physiology, Chromosomes analysis, Histones physiology
Abstract

Experimental data about the chemistry and the biology of chromosomal proteins are reviewed. Paragraphs include: aminoacid sequential data and post-translational covalent modications of histones, histone chemical differences in different tissues of the same species and in homologous organs of different species, histone synthesis subcellular localization and its association with DNA synthesis, histone synthesis transcriptional and translational control, histone synthesis during meiosis, oogenesis and early embryogenesis. The possible role of histones as controllers of gene expression is discussed and a model of primary structure of chromatine is proposed. The "acidic proteins" data concern the high tissue eterogenity of these proteins and their role in the steroid-hormon-controlled gene expression. The possible role of acidic proteins as general controllers of gene expression in eucariotic cells is discussed.

Published
1976

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