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The realisation of a remotely-controlled target-exchange system for the multi-detector array GALILEO has been proposed to the Mechanical Design and Machine Workshop Department of INFN Milano, with the following requirements: possibility of pre-loading 7-10 targets, including quartz and collimators for beam centering procedures; downstream location in front of the beam-dump, almost 3 m away from the scattering chamber; minimum material which can interact with the beam, and under vacuum working conditions, with pressures around 10−6 mbar. The system has been designed and built within the Mechanical Design and Machine Workshop Department of INFN-Milano and installed onto the GALILEO beam line at the LNL INFN laboratories in Legnaro.