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Your search keyword '"Agrusta M."' showing total 28 results
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28 results on '"Agrusta M."'

23. [Cimetidine and the hypothalamo-hypophysial-suprarenal axis].

Author

Loscalzo B, Agrusta A, Agrusta M, Cerciello A, Crisci A, and Trovato C

Subjects
Animals, Ascorbic Acid analysis, Cholesterol analysis, Corticosterone blood, Male, Rats, Cimetidine pharmacology, Guanidines pharmacology, Hypothalamo-Hypophyseal System drug effects, Pituitary-Adrenal System drug effects, Stress, Physiological metabolism
Abstract

The effects of cimetidine on experimental stress, induced by a long time fast and pylorus ligature, in male albino rats were investigated. The drug at the dose of 30 mg/kg was administered i.m. just after the operation and 12 h later. To evaluate the interference of cimetidine on the hypothalamo-hypophyseal-adrenal axis were dosed, in the rat, the level of adrenal ascorbic acid and cholesterol as well as corticosterone plasma levels. The results seem to suggest that cimetidine, in this experiment, is unable to modify stress induced changes.

Published
1981

24. [Cimetidine in experimental gastric ulcers induced by pyloric ligation].

Author

Loscalzo B, Agrusta A, Agrusta M, Cerciello A, Crisci A, and Trovato C

Subjects
Animals, Gastric Juice drug effects, Ligation, Male, Rats, Cimetidine therapeutic use, Guanidines therapeutic use, Pyloric Antrum physiology, Stomach Ulcer drug therapy
Abstract

Male albino rats of the Wistar strain, without food from 48 h, have been operated with pylorus ligature and treated with cimetidine, at the dose of 30 mg/kg i.m., just after the operation and 12 h later. Cimetidine reduced the size and the number of gastric ulcers induced by pylorus ligature, showing a significant protective effect. This action, due to the inhibition of gastric secretion induced by cimetidine, supports the hypothesis that the staunching of gastric juice (by pylorus ligature) plays a basic role in the pathogenesis of these experimental gastric ulcers.

Published
1981

25. [Glycosylated hemoglobin and raubasine in experimental streptozotocin diabetes].

Author

Loscalzo B, Agrusta A, Agrusta M, Ammaturo V, Crisci A, Genovese L, and Marino M

Subjects
Animals, Rats, Rats, Inbred Strains, Diabetes Mellitus, Experimental blood, Glycated Hemoglobin analysis, Secologanin Tryptamine Alkaloids, Yohimbine pharmacology
Abstract

Streptozotocin (Stz) diabetes was induced to study the changes of glycosylated hemoglobin in rats treated with raubasina (R), drug widely used in the vascular compliance of natural human diabetes. Raubasina reduced significantly the increase of glycosylated hemoglobin found in streptozotocin induced diabetes. These results support data obtained in clinical trials.

Published
1983

26. [Eseroline and hypophyseal-adrenocortical reactivity].

Author

Loscalzo B, Agrusta A, Agrusta M, Crisci A, Genovese L, and Marino M

Subjects
Adrenal Cortex chemistry, Analgesics, Opioid administration & dosage, Animals, Ascorbic Acid analysis, Cholesterol analysis, Corticosterone blood, Dose-Response Relationship, Drug, Female, Indoles administration & dosage, Injections, Intraperitoneal, Male, Rats, Adrenal Cortex metabolism, Analgesics, Opioid pharmacology, Corticosterone metabolism, Indoles pharmacology, Pituitary-Adrenal System drug effects
Published
1983

27. [Atmospheric pollutants and pregnancy: fetal toxicity of exposure to air polluted by combustion engine gas].

Author

Loscalzo B, Agrusta A, Agrusta M, Crisci A, Genovese L, and Marino M

Subjects
Abnormalities, Drug-Induced, Animals, Anthraquinones toxicity, Benzene toxicity, Carbon Monoxide toxicity, Embryonic and Fetal Development drug effects, Female, Fetal Resorption chemically induced, Gasoline, Hydrocarbons toxicity, Pregnancy, Rats, Rats, Inbred Strains, Air Pollutants toxicity, Fetus drug effects
Published
1985

28. [Glycosylated hemoglobin in experimental streptozotocin diabetes].

Author

Loscalzo B, Agrusta A, Agrusta M, Crisci A, Genovese L, and Marino M

Subjects
Animals, Rats, Rats, Inbred Strains, Diabetes Mellitus, Experimental blood, Glycated Hemoglobin analysis
Abstract

Streptozotocin (Stz) diabetes was induced in rats to study the changes in glycosylated hemoglobin. An increase of glycosylated hemoglobin had been found since the first days of the experiment. These results suggest that such a model may be used for the study of changes of glycosylated hemoglobin in diabetes.

Published
1983

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