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29 results on '"ADDISON'S disease"'

1. RUOLO DELLE HEAT SHOCK PROTEINS NELLA PATOGENESI DELLA MIASTENIA GRAVIS.

Author

Zummo, Leila and Gammazza, Antonella Marino

Subjects
*AUTOIMMUNE diseases, *ADDISON'S disease, *ALLERGIC encephalomyelitis, *IMMUNOGLOBULINS, *ACETYLCHOLINE, *NEUROTRANSMITTERS, *ARTHRITIS, *DIABETES, *ATHEROSCLEROSIS
Abstract

Myasthenia Gravis (MG) is an autoimmune disorder of the neuromuscolar junction mediated by specific antibodies to the nicotinic acetylcholine receptors. Several clinical and experimental studies have confirmed that the HSPs are involved in the process of regulation of some autoimmune disorders such as arthritis, diabetes, atherosclerosis and multiple sclerosis. The involvement of HSPs within different autoimmune disorders allows to hypothesize their presence in the pathogenesis of the MG, i.e. as suggested by the existence of a cross-reactivity among the antigenic epitopes of Hsp60 and AChR. Moreover, since a cross-reactivity between human and bacterial epitopes of Hsp60 has also been described, we would like to stress the role played by chronic and/or persistent infections, such as those from Chlamydia Trachomatis. [ABSTRACT FROM AUTHOR]

Published
2010
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3. La sopravvivenza dei pazienti affetti da morbo di Addison in Italia

Author

Garelli, Silvia

Subjects
Addison's Disease, Autoimmune Polyendocrine Syndromes, MED/13 Endocrinologia, Morbo di Addison, Insufficienza surrenalica primitiva, Sindromi poliendocrine autoimmuni, Primary adrenal insufficiency, Settore MED/13 - Endocrinologia
Abstract

Introduction: Survival of patients affected by Addison’s Disease (AD) is controversial, because only few studies have been published so far. We decided to evaluate survival of an Italian group of patients, affected by AD of various causes. Materials and Methods: We examinated 1315 patients (58.6% females and 41.4% males) affected by AD, followed-by Endocrine Units all over Italy: the sum of follow-up years was 16983. 70.5% of patients has autoimmune AD (AAD), 113 with APS-1 and 814 with con AAD not APS-1 correlated (AAD not APS-1); 29.5% has non autoimmune AD, 98 of which with post-tuberculosis AD (TBC-AD), 50 with AD due to malignancy (Tu-AD), 97 with congenital AD (Ge-AD) and 143 with AD due to other causes (Ac-AD). We analyzed mean age of diagnosis, years of follow-up and mean age at the end of follow-up, survival was evaluated with Kaplan-Meier analysis and Cox regression. Results were correlated with Italian population data, correlated for sex and age (ISTAT register). We also performed a similar analysis considering only those patients who terminated the follow-up (1006 subjects). Results: In APS-1 patients, mean age of diagnosis is 16.1±13.8 years, with 15 deaths in 113 subjects (13.3%) at a mean age of 32.5±18.4 years and a mean estimated survival (MES) of 40.4±5.8 years; in MAA non APS-1, mean age of diagnosis is 35.7±14.4 years, with 18 deaths in 814 subjects (2.2%) at 77.9±13.3 years of age and a MES of 56.1±3.8 years; in TBC-AD, mean age of diagnosis is 50.1±15.7 years, with 11 deaths in 98 subjects (11.2%) at a mean age of 81.1±7.4 years and MES of 42.5±4.1 years; in Tu-AD, mean age of diagnosis is 57.9±15.5 years, with 12 deaths in 50 subjects (24%) at 65.6±14.4 years of age and a MES of 11.3±5.8 years; in Ge-AD, mean age of diagnosis is 7.3±10 years, with 4 deaths in 97 subjects (4.1%) at a mean age of 16.7±4.3 years and a MES of 41.1±1.8 years; in Ac-AD, mean age of diagnosis is 43±19.5 years, with 5 deaths in 143 subjects (3.5%) at a mean age of 55.2±40 years and a MES of 44.4±1.8 years. Comparing mean estimated survival of each subgroup with Italian matched population, only APS-1 and Tu-AD appear lower. Comparing subgroups head to head, Tu-AD patients’ survival is lower than all other groups (p

Published
2016

4. Malattia celiaca e patologie endocrine autoimmuni

Author

Iughetti, Lorenzo, Bruzzi, Patrizia, Predieri, Barbara, Berri, Rossella, BI BIASE AR, and Balli, Fiorella

Subjects
patologie tiroidee, diabetes mellitus type 1, sindromi poliendocrine autoimmuni. celiac disease, Addison’s disease, malattia di Addison, autoimmune polyglandular syndrome, hypoparathyroidism, malattia celiaca, growth hormone deficit, ipoparatiroidismo, diabete mellito tipo 1, thyroid disorders, autoimmune hypophysitis, gluten-free diet, glutine, dieta senza glutine, deficit di ormone della crescita, ipofisite autoimmune, gluten
Published
2008

6. [ADDISON'S DISEASE IN CHILDHOOD].

Author

MUSSA GC and ZORATTO E

Subjects
Adrenal Insufficiency, Child, Humans, Hypoadrenocorticism, Familial, Addison Disease
Published
1964

7. [TEST OF ADRENAL CORTEX STIMULATION WITH SYNTHETIC ACTH (BETA 1-24-CORTICOTROPIN)].

Author

BUSONERA G, MORELLI M, and BENEDETTI A

Subjects
Adolescent, Hypoadrenocorticism, Familial, 17-Ketosteroids, Addison Disease, Adrenal Cortex, Adrenal Cortex Hormones, Adrenal Insufficiency, Adrenalectomy, Adrenocorticotropic Hormone, Cosyntropin, Cushing Syndrome, Hypertrichosis, Pituitary-Adrenal Function Tests, Urine
Published
1963

8. [ADDISON'S DISEASE IN THE CHILD. CASE PRESENTATION OF DISSOCIATED ADRENAL INSUFFICIENCY DUE TO PROBABLE SELECTIVE ENZYMATIC DEFICIT].

Author

BATTISTINI A and FAIENZA C

Subjects
Child, Hypoadrenocorticism, Familial, 17-Ketosteroids, Addison Disease, Adrenal Cortex Hormones, Adrenal Insufficiency, Aldosterone, Carbohydrate Metabolism, Corticosterone, Cortisone, Electroencephalography, Metabolic Diseases, Mixed Function Oxygenases, Pathology, Penicillins, Pituitary-Adrenal Function Tests, Prednisolone, Radiography, Thoracic, Water-Electrolyte Balance
Published
1964

9. [METHODOLOGICAL DATA ON THE DYNAMIC EVALUATION OF THE DIENCEPHALON-ANTERIOR PITUITARY-ADRENAL CORTEX SYSTEM].

Author

FERRARI E and PIOTTI LE

Subjects
Acromegaly, Addison Disease, Adrenal Cortex, Adrenocorticotropic Hormone, Cushing Syndrome, Dexamethasone, Diagnosis, Diencephalon, Dwarfism, Dwarfism, Pituitary, Endocrinology, Hypopituitarism, Ketones, Metyrapone, Mineralocorticoid Receptor Antagonists, Obesity, Pharmacology, Physiology, Pituitary Diseases, Pituitary Gland, Pituitary Hormones, Pituitary Hormones, Posterior, Pituitary-Adrenal Function Tests, Pyrogens
Published
1964

14. [DIAGNOSIS AND TREATMENT OF ADDISON'S DISEASE].

Author

LEGRAMANTE A and ZILLI E

Subjects
Hypoadrenocorticism, Familial, Addison Disease, Adrenal Cortex Hormones, Adrenal Insufficiency, Adrenocorticotropic Hormone, Aldosterone, Androgens, Cortisone, Desoxycorticosterone, Diabetes Mellitus, Diagnosis, Hypertension, Pathology, Prednisolone, Prednisone, Therapeutics, Thyroid Diseases
Published
1963

15. [STUDY OF ADRENAL CORTEX FUNCTION AFTER ADMINISTRATION OF HYDROCHLOROTHIAZIDE IN NORMAL SUBJECTS AND PATIENTS WITH ADRENAL GLAND DISEASES].

Author

IACONO G, BRANCACCIO A, D ALESSANDRO B, DELUCA R, and REPOLE R

Subjects
Humans, Hypoadrenocorticism, Familial, 17-Hydroxycorticosteroids, 17-Ketosteroids, Addison Disease, Adrenal Cortex, Adrenal Gland Diseases, Adrenal Insufficiency, Adrenocortical Hyperfunction, Androsterone, Cushing Syndrome, Dehydroepiandrosterone, Hydrochlorothiazide, Hypopituitarism, Pharmacology, Pituitary-Adrenal Function Tests
Published
1964

27. [RESEARCH ON THE MECHANISM OF THE DIURETIC ACTION OF TRIAMTERENE. I. RELATIONS TO THE PERIPHERAL INHIBITION OF ALDOSTERONE].

Author

AMBROSOLI S, BARONIO G, FERIOLI V, PENATI MR, PRATI G, and SCARPIC L

Subjects
Rats, Addison Disease, Adrenalectomy, Adrenocortical Hyperfunction, Aldosterone, Betamethasone, Biomedical Research, Cortisone, Desoxycorticosterone, Diuresis, Diuretics, Hydrochlorothiazide, Mineralocorticoid Receptor Antagonists, Pharmacology, Pituitary-Adrenal Function Tests, Pterins, Research, Triamterene
Published
1964

29. [ALDOSTERONURIA AND ADRENAL CORTICAL FUNCTIONAL CAPACITY IN ADDISON'S DISEASE].

Author

ORABONA ML, CHIUMMO R, MATARAZZO C, and PATRUNO L

Subjects
Hypoadrenocorticism, Familial, 17-Ketosteroids, Addison Disease, Adrenal Cortex, Adrenal Cortex Hormones, Adrenal Insufficiency, Adrenocorticotropic Hormone, Aldosterone, Blood Chemical Analysis, Electrolytes, Pharmacology, Pituitary-Adrenal Function Tests, Urine
Published
1964

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