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Minimization of hospital lengths of stay has always been a key goal for healthcare systems. More so during the current COVID-19 pandemic. In fact, we have faced a reduction in no-COVID-19 admissions with the generation of huge backlogs. Low-risk patients undergoing elective percutaneous coronary intervention (PCI) can be candidate for short-term hospitalization, with consequent reduction of waiting lists. Several single-center and multicenter observational studies, multiple randomized trials and some meta-analyses have addressed this topic.In this position paper, we present a proposal for short hospitalization for elective PCI procedures in selected patients who present complications only exceptionally and exclusively immediately after the procedure, if the inclusion and exclusion criteria are met. Each Center can choose between admission in day surgery or one day surgery, extending hospital length of stay only for patients who present complications or who are candidate for urgent surgery. Short-term hospitalization considerably reduces costs even if, with the current model, it generally results in a parallel reduction in reimbursement. Hence, we present an actual model, already tested successfully in an Italian hospital, that warrants sustainability. This approach can then be tailored to single Centers.

The current COVID-19 pandemic has renewed interest in providing healthcare services based on the implementation of innovative technologies. Such strategy capillarizes the therapeutic opportunities for larger urban areas, mostly when people are living under extraordinarily difficult circumstances. Improving care delivery in cardiovascular diseases appears particularly feasible when telemedicine is pursued, especially with regard to baseline standard 12-lead electrocardiography, ambulatory electrocardiographic monitoring, and 24-hour ambulatory blood pressure monitoring. Nowadays, these first-line cardiovascular examinations are also available in health centers and pharmacies, and in recent months, there has been an increasing demand of such local services in the absence of specific rules and regulations regarding technical requirements and standards of interpretation that ensure a high quality clinical consultation.The purpose of this position paper is to provide critical requirements for the type/model of devices to be used, training dedicated to healthcare personnel, ensuring security of sensitive data, highlighting type of platforms to be used, as well as for maintaining high reporting quality and standards.

The prescription appropriateness of direct oral anticoagulants (DOACs [dabigatran, rivaroxaban, apixaban, and edoxaban]) is carefully regulated, taking into account the criteria established in phase III trials and listed in the summary of the product characteristics of the four DOACs. In clinical practice, prescriptions are not always in compliance with established indications. In particular, the use of doses lower than those recommended in drug data sheets is relatively frequent. Literature data show that the inappropriate prescription of DOAC doses causes drug underexposure and an up to three-fold increase in the risk of stroke/transient ischemic attack, systemic thromboembolism, and hospitalizations. Possible causes of the deviation between the dose that should be prescribed and that actually employed may include erroneous prescriptions, an overstated bleeding risk perception, and the presence of frail patients, who were not included in pivotal trials. For these reasons, we summarize DOAC indications and contraindications and suggest the appropriate use of DOACs in common clinical scenarios, in accordance with what international guidelines and national and international health regulatory agencies recommend.

The triple therapy (angiotensin-converting enzyme [ACE] inhibitors or angiotensin receptor blockers, beta-blockers, mineralocorticoid receptor antagonists) certificated by the 2012 guidelines for symptomatic patients with heart failure and reduced ejection fraction, reaffirmed in the following document of 2016 with the introduction of angiotensin receptor-neprilysin inhibitors (ARNI), has not yet reached an adequate implementation in clinical practice (where the majority of patients is only treated with the double treatment of ACE-inhibitors or angiotensin receptor blockers and beta-blockers). Among the reasons for this general failure, we should consider the enrollment of unselected cases from the real world, without exclusion criteria for age, comorbidity and stage of the disease, the therapeutic inertia of many cardiologists and not least the clinical and organizational complexity of the conventional scheme of implementation of therapy indicated by the guidelines. Not only the prescription of triple therapy is inadequate, but also the "target doses" defined by the large randomized controlled trials should be considered unrealistic in the majority of patients, who often achieve a therapeutic effect at lower doses, generally better tolerated ("target effect"). The new guidelines forthcoming will certify a further step forward with the quadruple therapy (sodium-glucose co-transporter 2 inhibitors, ARNI, beta-blockers and mineralocorticoid receptor antagonists), underlining how a fourfold intervention with different pharmacological mechanisms is able to determine the greatest benefits in patients with systolic heart failure. The discussion is open on the possibility of simplifying and speeding up the conventional implementation scheme of treatment, exploiting the ability of all these pharmacological principles to exert a significant and rapid favorable effect on prognosis already at a low dose in the first 4-8 weeks of treatment.

Sacubitril/valsartan (S/V) has been shown to reduce the risk of cardiovascular death or heart failure hospitalization and improve symptoms in chronic heart failure with reduced ejection fraction compared to enalapril. After 7 years since the publication of the results of PARADIGM-HF, further insight has been gained with potential new indications. Two prospective randomized multicenter studies (PIONEER-HF and TRANSITION) in patients hospitalized for acute heart failure (AHF) have shown an improved clinical outcome and biomarker profile as compared to enalapril, and good tolerability, safety and feasibility of initiating in-hospital administration of S/V. Furthermore, some studies have highlighted the favorable effects of S/V in attenuating adverse myocardial remodeling, supporting an early benefit after treatment. Observational data from non-randomized studies in AHF report that in-hospital and pre-discharge prescription of evidence-based drugs associated with better survival still remains suboptimal. Additionally, the COVID-19 pandemic has also negatively impacted on outpatient activities. Therefore, hospitalization, a real crossroads in the history of heart failure, must become a management and therapeutic opportunity for our patients. The objective of this ANMCO position paper is to encourage and facilitate early S/V administration in stabilized patients during hospitalization after an AHF episode, with the aim of improving care efficiency and clinical outcome.

The COVID-19 pandemic and its impact on patients with cancer and cardiovascular disease have confirmed the particular vulnerability of this population. Indeed, not only a higher risk of contracting the infection has been reported, but also an increased occurrence of a more severe course and unfavorable outcome. Beyond the direct consequences of COVID-19, the pandemic has an enormous impact on global health systems. Screening programs and non-urgent tests have been postponed; clinical trials have suffered a setback. Similarly, in the area of cardiology care, a significant decline in ST-elevation myocardial infarction accesses and an increase in cases of late presenting heart attacks with increased mortality and complication rates have been reported. Health care systems must therefore get ready to tackle the "rebound effect" that will likely show a relative increase in the short and medium term incidence of diseases such as heart failure, myocardial infarction, arrhythmias and cardio- and cerebrovascular complications. Scientific societies are taking action to provide general guidance and recommendations aimed at mitigating the unfavorable outcomes of this pandemic emergency. Cardio-oncology, as an emerging discipline, is more flexible in modulating care pathways and represents a beacon of innovation in the development of multi-specialty patient management. In the era of the COVID-19 pandemic, cardio-oncology has rapidly modified its clinical care pathways and implemented flexible monitoring protocols that include targeted use of cardiac imaging, increased use of biomarkers, and telemedicine systems. The goal of these strategic adjustments is to minimize the risk of infection for providers and patients while maintaining standards of care for the treatment of oncologic and cardiovascular diseases. The aim of this position paper is to evaluate the impact of the COVID-19 pandemic on the management of cardio-oncologic patients with the-state-of-the-art knowledge about SARS-CoV-2 and COVID-19 in order to optimize medical strategies during and after the pandemic.

The specific traits of the methodology of theology as well as the peculiarities of its scientific knowledge inevitably influence the extralinguistic and intralinguistic features of theological scientific works, which is especially reflected in the lexical layer. Tis paper deals with the analysis of the vocabulary of popular scientific theological works of eminent authors in the Serbian language in relation to academic papers as basic representatives of the scientific style of theology. The results obtained by statistical analysis of the vocabulary of the works of the two mentioned substyles enabled their contrastive analysis. In addition, atypical elements were pointed out – the expressive and emotional markers and stylistic figures of popular science theological works.

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This article analyses Italian illustrated editions of Little Women published between 1908 and 1945. After an overview of the publishing history of the novel in Italy, the paper will examine Italian illustrations as hermeneutic tools in order to examine their ideological function in the representation of gender. The belated reception of Alcott’s novel in Italy, caused by its representation of a nonconformist educational model for girls, is mirrored in the tension between the nationalistic drive and the influence of foreign models that can be pinpointed in the illustrated editions. By analyzing adaptations of American illustrations, original Italian creations, and omissions of iconic illustrations, this paper will unveil how much the visual element is embedded in the Italian historical and cultural context, as the choice (or omission) of particular images impacted the interpretation of the book. By examining the Italian editions of Little Women published in this time frame, we will also be able to retrace the links with the American illustrated history of the book and bear testimony to the powerful impact of the 1934 film version on printed editions.

La Sociedad de Estudios Kantianos en Lengua Española (SEKLE) invita a participar en el Congreso Internacional que tendrá lugar en Santiago de Compostela del 15 al 19 de julio del 2024. El VI Congreso Internacional de la SEKLE celebra no solo el encuentro bienal de esta Sociedad de Estudios Kantianos sino también el tricentenario del nacimiento de Immanuel Kant (1724-1804). El lema Caminos del pensar, evoca metafóricamente tanto el Camino de Santiago y la bella ciudad anfitriona, como los múltiples caminos abiertos por el pensar kantiano a tres siglos de su nacimiento. Consideramos la historia evolutiva de su pensamiento, que, desde nuestro punto de vista, no recorre uno, sino varios caminos, lo que también vale para su historia efectual. Etimológicamente la palabra 'camino' o 'caminos' sugiere el problema del método o de los métodos del pensamiento de Kant y existe en nuestro pensador incluso “un camino que todavía no ha sido nunca hollado” (KrV, A 98), a saber, el de la Deducción trascendental de las categorías. Muchos son los caminos, tanto nacionales como internacionales, que pueden traer a las investigadoras y a los investigadores kantianos a Santiago de Compostela, en ocasión del tricentenario de su nacimiento. Además de los temas mencionados, son bienvenidas las contribuciones sobre cualquier otro aspecto del pensamiento de Kant. Los idiomas del congreso son: español, alemán, portugués, inglés, italiano, francés y gallego.

This comment on Bottaccioli & Bottaccioli’s (2024a) article critically analyzes Franz Alexander’s role in developing contemporary psychosomatics in both its innovative aspects and limitations. On the one hand, Alexander contributed to emancipating the explanation of physical symptoms from the classical approach of the early 20th century stiffened on the model of hysterical conversion and promoted the organization of the international psychosomatic movement, including the Italian one. On the other hand, his limitations mainly concern the theoretical approach typical of 20th century psychoanalysis: adopting a one-dimensional model centered on intrapsychic conflict and the indeterminacy – necessary for the time – of a biological “X” factor as mediator. Instead, in the second half of the 20th century, a deficit-centered model of explanation (e.g., alexithymia) and complexity (e.g., biopsychosocial model) emerged, in which various moderating biomedical, psychological, and socio-cultural factors assume different relative weights in the explanation of physical illnesses and the clinical management of patients. [ABSTRACT FROM AUTHOR]

Sixty years after the death of Franz Alexander, it is necessary to investigate what is alive and what is dead in his thought about psychosomatics, focusing in particular on the notions of emotion and vegetative neurosis as central to his model of explanation. It is then worth noting, in the light of the developments after Alexander, the today’s difficulty in supporting psychosomatics as an autonomous discipline, to the point of questioning the legitimacy of the expression itself: Bottaccioli & Bottaccioli’s (2024a) proposal to identify it with Psycho-Neuro-EndocrineImmunology (PNEI) must be measured in this problematic context. In any case, the always valid need remains, already supported by Alexander, for a unitary, “holistic” consideration of the human being, sick and healthy. However, this is a paradigm that has to be justified and clarified conceptually in the actual role it plays as an inspirer of research and specific explanations. [ABSTRACT FROM AUTHOR]

Atherosclerosis often affects the coronary arterial tree. Very often the disease does not translate in significant narrowing of the vessels, thus determining only a non-obstructive disease. This condition that is described as non-obstructive coronary artery disease (NobsCAD) should be distinguished from the absence of disease (i.e. smooth coronary arteries) as it carries a specific prognostic value. The detection and reporting of NobsCAD should prompt preventive measures that can be individualized upon the degree of the underlying burden of disease. The accompanying clinical condition, the other cardiovascular risk factors present, and the description of the severity and extent of NobsCAD should provide the framework for an individualized treatment that should also consider the best available evidences and scientific guidelines. The description of NobsCAD represents an important information to be collected whenever a coronary angiogram (both invasive and non-invasive) is performed. Treating the patient according to the presence and extent of NobsCAD offers prognostic benefits well beyond those offered by considering only the traditional cardiovascular risk factors. In order to reach this goal, NobsCAD should not be confused with the absence of coronary atherosclerosis or even ignored when detected as if it was a trivial information.

The COVID-19 pandemic represents an unprecedented event that has brought deep changes in hospital facilities with reshaping of the health system organization, revealing inadequacies of current hospital and local health systems. When the COVID-19 emergency will end, further evaluation of the national health system, new organization of acute wards, and a further evolution of the entire health system will be needed to improve care during the chronic phase of disease. Therefore, new standards for healthcare personnel, more efficient organization of hospital facilities for patients with acute illnesses, improvement of technological approaches, and better integration between hospital and territorial services should be pursued. With experience derived from the COVID-19 pandemic, new models, paradigms, interventional approaches, values and priorities should be suggested and implemented.

This ANMCO position paper aims to analyze the complex action of sodium-glucose co-transporter 2 inhibitors at the level of the kidney and cardiovascular system, focusing on the effect that these molecules have shown in the prevention and treatment of heart failure in diabetic and non-diabetic subjects. The goal was pursued by comparing the data generated with pathophysiology studies and with multicenter controlled studies in large populations. In accordance with the analysis carried out in the document, the following recommendations are issued: (i) canagliflozin, dapagliflozin, empagliflozin and ertugliflozin are molecules recommended for the prevention of heart failure hospitalizations in type 2 diabetic subjects; (ii) canagliflozin and dapagliflozin are recommended for the prevention of heart failure hospitalizations in type 2 diabetic subjects with severe chronic kidney disease, dapagliflozin proved to be safe and effective also in diabetic subjects; and (iii) dapagliflozin and empagliflozin are recommended to reduce the combined risk of heart failure and cardiovascular death in diabetic and non-diabetic subjects with heart failure and reduced ejection fraction.

The European Society of Cardiology guidelines on non-ST-elevation acute coronary syndromes suggest different temporal strategies for the angiographic study depending on the risk profile. The scientific evidence underlying the guideline recommendations and the critical issues currently existing in Italy that often do not allow either an extended strategy of revascularization within 24 h or the application of the principle of the same day transfer from a spoke to a hub center are analyzed. The position paper focuses, in particular, on the subgroup of patients with a defined diagnosis of non-ST-elevation myocardial infarction by proposing a timing of coronary angiography/revascularization that takes into account the available scientific evidence and the organizational possibilities of a considerable part of national cardiology services.

In over a year, the COVID-19 pandemic caused 2.69 million deaths and 122 million infections. Social isolation and distancing measures have been the only prevention available for months. Scientific research has done a great deal of work, developing in a few months safe and effective vaccines against COVID-19. In the European Union, nowadays, four vaccines have been authorized for use: Pfizer-BioNTech, Moderna, ChAdOx1 (AstraZeneca/Oxford), Janssen (Johnson & Johnson), and three others are currently under rolling review.Vaccine allocation policy is crucial to optimize the advantage of treatment preferring people with the highest risk of contagion. These days the priority in the vaccination program is of particular importance since it has become clear that the number of vaccines is not sufficient for the entire Italian population in the short term. Cardiovascular diseases are frequently associated with severe COVID-19 infections, leading to the worst prognosis. The elderly population suffering from cardiovascular diseases is, therefore, to be considered a particularly vulnerable population. However, age cannot be considered the only discriminating factor because in the young-adult population suffering from severe forms of heart disease, the prognosis, if affected by COVID-19, is particularly ominous and these patients should have priority access to the vaccination program. The aim of this position paper is to establish a consensus on a priority in the vaccination of COVID-19 among subjects suffering from different cardiovascular diseases.

The treatment of patients with advanced acute heart failure is still challenging. Intra-aortic balloon pump (IABP) has widely been used in the management of patients with cardiogenic shock. However, according to international guidelines, its routinary use in patients with cardiogenic shock is not recommended. This recommendation is derived from the results of the IABP-SHOCK II trial, which demonstrated that IABP does not reduce all-cause mortality in patients with acute myocardial infarction and cardiogenic shock. The present position paper, released by the Italian Association of Hospital Cardiologists (ANMCO), reviews the available data derived from clinical studies. It also provides practical recommendations for the optimal use of IABP in the treatment of cardiogenic shock and advanced acute heart failure. Data deriving from a national survey in Italian hospitals about IABP use are also provided.

The “Aldo Beldì” archival collection was donated to the Novara State Archives in 2001 by Paolo Beldì. He wanted to avert the dispersion of the professional papers of his father, owner of a major advertising firm from 1945 to 2000. Its reorganization, carried out in 2020, led to the rediscovery of the life and activities of the publicist, born in Novara on May 7, 1922. After studying at the Technical Commercial Institute “Galileo Ferraris,” Beldì joined an amateur drama company in Novara. In 1945, after the war and after a brief stint with the Società Irrigazione Est Sesia and Vittorio Orsini’s Notorius graphic design studio, he opened his own advertising firm. Between 1948 and 1956 he began his work as an illustrator for the sports newspapers “L’Azzurro” and “Forza Novara”. Supported by the group of friends he used to meet at the Menabrea, Coccia and Faraggiana cafes, Beldì immediately showed his creative skills as an exhibition hall fitter: during the 1947 Milan Fair he advertised Renato Bialetti’s (1923-2016) coffee makers by installing a huge mocha pot at the entrance to the exhibition from which coffee came out. The cooperation with Bialetti continued with the design of several exhibition spaces in Milan from 1954 to 1960 and the development of one of the first TV clips for Carosello in 1958. He also had important cooperations with Mario Pavesi (1909-1990) and Carlo Doppieri (1895-1969). In 1973 Studio Beldì started a fruitful collaboration with the Parmigiano Reggiano Cheese Consortium, followed in 1975 by the first works for the Gorgonzola Cheese Protection Consortium, for which it developed graphic and TV advertising campaigns. In the 1980s, it launched the advertisements for Giocattoli Mattel and for large-scale events, such as the “Novarassima” sports and cultural festivals (1982-1984) and the 1987 “Stresa d’Oro”. AldoBeldì was named Cavaliere della Repubblica in 1960; he was appointed Commendatore by President Scalfaro. He died in Novara on February 27, 2000, at the age of 77. [ABSTRACT FROM AUTHOR]

The field of epistemic logic developed into an interdisciplinary area focused on explicating epistemic issues in, for example, artificial intelligence, computer security, game theory, economics, multiagent systems and the social sciences. Inspired, in part, by issues in these different ‘application’ areas, in this paper we propose an epistemic logic model for metadata extracted from scientific papers on COVID-19. More in details, we introduce a new predicate ξ – reads ‘extract’ – and a structure S to syntactically and semantically analyse metadata extracted with systems for extracting structured metadata from scientific articles in a born-digital form. These systems will be considered, in the logical model created, as ‘knowledge extraction agents’ (henceforth KEA). In this case KEA taken into consideration are CERMINE and TeamBeam. In an increasingly data-driven world, modelling data or metadata means to help systematise existing information and support the research community in building solutions to the COVID-19 pandemic.

The specific traits of the methodology of theology as well as the peculiarities of its scientific knowledge inevitably influence the extralinguistic and intralinguistic features of theological scientific works, which is especially reflected in the lexical layer. Tis paper deals with the analysis of the vocabulary of popular scientific theological works of eminent authors in the Serbian language in relation to academic papers as basic representatives of the scientific style of theology. The results obtained by statistical analysis of the vocabulary of the works of the two mentioned substyles enabled their contrastive analysis. In addition, atypical elements were pointed out – the expressive and emotional markers and stylistic figures of popular science theological works.

Similar to many other countries, journalistic production in China during the first half of 2020 was dominated on a thematic level by the COVID-19 pandemic. The trend included the mouthpiece of the Central Committee of the Chinese Communist Party (CCP), Renmin Ribao. Its news and commentary articles, which are widely republished by other media, influence the country’s political life, and contribute to the process of meaning generation in the news discourse and to the CCP’s effort to align Chinese citizens to official narratives. Renmin Ribao can therefore provide a relevant source to investigate the relationship between political power and the COVID-19 pandemic, starting from the hypothesis that the paper’s narrative would aim at discursively turning the international health crisis into a piece of positive propaganda. This study aims to verify whether and how the paper did so, and to question the assumption that the outlet’s media discourse can be equated to the CCP official discourse. The research is developed as a case study and blends quantitative and qualitative tools grounded on Applied Linguistics, Discourse-Historical Approach, and Frame Analysis, in order to analyse a corpus of commentaries that have appeared in the outlet’s online edition in 2020. By applying a Genre Analysis approach, the study also offers insights into the possibility to identify distinguishing characteristics and communicative goals in the different sub-genres of Renmin Ribao commentaries.

In the mid 1920s, Virginia Woolf was engaged in a dispute with the American critic Logan Pearsall Smith on “the ethics of writing articles at high rates for fashion papers”. Harper’s Bazaar, a commercial magazine to which Woolf contributed four short stories between 1930 and 1939, was a feminine periodical that exploited modernism’s distinction and high cultural capital to captivate a sophisticated, but essentially middle-class, readership by selling the illusion of upward cultural mobility. Although Woolf referred to her high-quality contributions to Harper’s Bazaar as “pot boiling stories for America” written “to make money”, it seems clear that her own engagement with a middlebrow publishing venue did not in the least affect her reputation as a highbrow intellectual and was indeed typical of the multifaceted, reciprocal relationship between the magazine and high modernism in a context in which mobility also meant redrawing the boundaries between intellectual and popular culture. The publication of modernist content within the glossy pages of Harper’s Bazaar was advantageous to both modernists seeking to maintain their celebrity status and the periodical itself, which attempted to cultivate and sustain a refined audience. Much in line with her work of the 1930s, Woolf’s short stories engaged with social and ethical issues such as the righteousness of penetrating other people’s lives and innermost truths (“In the Looking Glass”), violence and decay (“The Shooting Party”), capitalism and antisemitism (“The Duchess and the Jeweler”), human and non-human worlds (“Lappin and Lapinova”). Though often considered as non-canonical in terms of both their rather prosaic plot as well as characterisation, and the commercial venue in which they appeared, the stories Woolf wrote for Harper’s Bazaar reflect the preoccupations of the last decade of her career and are indicative of the tensions between high and low in modernist culture.

SYSTEMATIC BIBLIOGRAPHY OF PAPERS ON PUBLISHED DIALECT MATERIAL

L’objectiu d’aquest article és estudiar la importància que té l’arxiu com a eina de construcció d’una identitat nacional i si a través de la seva organització es pot veure si la dita construcció nacional ha estat reeixida o no. En aquest sentit, s’agafa l’exemple de l’Arxiu Històric Nacional d’Espanya i s’analitza des de l’organització dels primers arxius en territori espanyol fins a la construcció de l’Arxiu Històric Nacional a finals del segle xix. Mitjançant aquesta anàlisi també es posa en relleu el paper que va tenir la Història en la formació de la identitat nacional i la seva interrelació amb l’arxiu. Una ciència no podria ser sense l’altre.

Studia theodisca XXIX (2022) - Call for Papers

In patients with cardiac implantable electronic devices (CIEDs) (implantable cardioverter-defibrillators [ICDs] and pacemakers [PMs]), the potential risk of suddenly being unable to drive, and hence of causing road accidents, is higher than in the general population. In ICD patients, this risk stems from the possibility that an arrhythmic event leading to loss of consciousness may occur while driving. In PM patients, it may be the result of a device malfunction in a PM-dependent patient. To determine a CIED patient's ability to drive, two variables must be taken into account: (i) the risk of events, which depends on the type of underlying heart disease (ICD patients have a higher risk than PM patients); (ii) the time spent driving and the type of vehicle driven (professional drivers are at higher risk than private drivers). This position paper reports the recommendations of the Italian Association of Arrhythmology and Cardiac Pacing (AIAC) regarding driving by patients with CIEDs, on the basis of the available literature and the European reference recommendations.

The problems posed by Leonardo’s pathographies written by Freud are examined. The historical path of the problem of the relationship between genius and psychopathology is reconstructed, showing that psychoanalysis fits into a very active vein at the end of the 19th century, expressing different theoretical approaches with which Freud relates. The interest for the problem then continued, with alternate answers, until the current days. The distortions made by Freud in Leonardo’s pathographical description are examined; these distortions are extensively examined by several authors, which, however, is not distant from what Freud implements in his other works, nor from what other pathographists of the time did. It is a common behavior in the history of science and well known in modern epistemology that identifies in the development of theories also the importance of rhetorical tools with which scientists support them. It is emphasized that one cannot read particular psychological aspects in these Freudian behaviors, making in fact a pathography of the author of pathographies, but only lead his work to the coherence of the historical contexts in which he operates. [ABSTRACT FROM AUTHOR]

This data paper presents the creation of a database bringing together all the French municipalities while giving a specific place to those which have undergone a merger process between 2012 et 2022: "the new municipalities" (communes nouvelles). Potential data gap and consistency issues arise with the creation of these new territorial entities aggregating municipal mergers. Using data from official statistics (INSEE - National Institute for Statistics and Economic Studies - and IGN - National Geographic Institute), this paper describes a process of compilation and aggregation of data. The method is detailed here, to allow its reproducibility.

Writing Studies scholars have raised concerns about framing student struggles to integrate secondary sources as an ethical problem of plagiarism. They propose, instead, framing student citation practices as transitional markers of development in which students use patchwriting to learn the discursive norms and values of academia. Patchwriting as a literacy tool for transfer of knowledge raised questions for me about whether students develop other scaffolds to aid in learning transfer. In this pilot study, I investigate student use of anchor sources, the “perfect source” that frames a student’s central argument, rhetorical structure, and/or purpose. Based on a random sample of a nationwide corpus of First-Year Writing research papers from 16 US institutions, findings show that 21 of 30 research papers (70%) revealed evidence of an anchor source. Six of the 9 papers without anchor sources show evidence of significant rhetorical problems. Results suggest evidence of knowledge transfer, as well as pedagogical implications for supporting this transitional stage in student development.

The street artist Ernest Pignon-Ernest, between 1988 and 1990, stuck some serigraphs inspired by Caravaggio's paintings to the walls of corners and streets in Naples. These interventions, epiphanic visual narratives, are presented here as forms of street art of a highly theatrical nature. The spatio-temporal dimension they give life will be read as a scene, at the same time real and symbolic, capable of revealing what the social order would tend to hide or forget.

El present article analitza la relació epistolar entre el doctor Joan Solé i Pla i Josep Subirà Puig, dos familiars que des de Barcelona i Madrid es van comprometre amb l’ajut material i la promoció dels voluntaris espanyols i catalans a les files de la Legió Estrangera francesa durant la Primera Guerra Mundial. A través de la seva correspondència busquem analitzar les projeccions nacionals en disputa dels discursos sobre els voluntaris i comprovar una qüestió escassament treballada: la important cobertura i organització de la propaganda sobre els voluntaris impel·lida per Josep Subirà, qui, malgrat tot, va mantenir amb Solé i Pla una relació estreta marcada per la cordialitat familiar i l’entusiasme per les mútues activitats aliadòfiles.

(Series Information) European Papers - A Journal on Law and Integration, 2017 2(1), 403-410 | European Forum Insight of 21 May 2017 | (Table of Contents) I. Introduction. - II. The White Paper. - III. The Free Trade Agreement. - IV. The customs agreement. - V. Conclusion. | (Abstract) The 29 March 2017 is now set to become the historical day Art. 50 TEU was triggered for the first time ever. Equally, unprecedented negotiations, in which the United Kingdom and the European Union will settle their divorce, will follow. With the aim of proving that the UK Government has the necessary negotiating strategy, it recently published a White Paper on its exit from and new partnership with the EU. Despite the promises, this Paper is far from providing certainty and clarity. However, it is also a step away from a previous superficial and simplistic approach to Brexit. In this Insight, I explain why the White Paper is riddled with contradictions and why, nonetheless, this confusing and vague exposition of what the UK will be seeking to achieve from its withdrawal is a welcome though disguised acknowledgment of the complexities that Brexit will entail.

The new coronavirus disease 2019 (COVID-19), which is causing hundreds of thousands of deaths worldwide, is complex and can present with a multi-organ localization. One of its worst complications is an interstitial pneumonia with acute respiratory failure also known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which requires non-invasive or invasive ventilation. A severe coagulopathy with poor prognosis is found in 5-10% of cases. SARS-CoV-2 is manifesting as a multi-dimensional disease and, recently, unique co-existing pathophysiological and clinical aspects are being defined: (i) an increased immune and inflammatory response with the activation of a cytokine storm and consequent coagulopathy, which promote both venous thromboembolic events and in situ thrombosis localized in small arterioles and pulmonary alveolar capillaries; (ii) a high intrapulmonary shunt, which often accounts for the severity of respiratory failure, due to reduced hypoxic pulmonary vasoconstriction with pulmonary neo-angiogenetic phenomena. Furthermore, the high incidence of venous thromboembolism in COVID-19 patients admitted to the intensive care unit and the autoptic findings of in situ micro-thrombosis at the pulmonary vascular level, suggest that in this disease coagulopathy, unlike septic disseminated intravascular coagulation, is driven towards a hyper-thrombogenic state, giving rise to a debate (with ongoing studies) about the preventive use of anticoagulant doses of heparin to reduce mortality. The aim of this position paper from the Italian Association of Hospital Cardiologists (ANMCO) is to highlight the main implications that COVID-19 infection has on the pulmonary circulation from a pathophysiological, clinical and management point of view.

Given the high prevalence of preexisting cardiovascular diseases and the increased incidence of adverse cardiovascular events in patients hospitalized for SARS-CoV-2 infection, the identification of optimal antithrombotic approaches in terms of risk/benefit ratio and outcome improvement appears crucial in this setting. In the present position paper we collected current evidence from the literature to provide practical recommendations on the management of antithrombotic therapies (antiplatelet and anticoagulant) in various clinical contexts prevalent during the SARS-CoV-2 outbreak: in-home management of oral anticoagulant therapy; interactions between drugs used in the SARS-CoV-2 infection and antithrombotic agents; in-hospital management of antithrombotic therapies; diagnosis, risk stratification and treatment of in-hospital thrombotic complications.

The SIML Position Paper dedicated to asbestos (PPA) is addressed (mainly) to competent practitioners (CP) for the purposes to provide a guidance about a set of items classified as markedly interesting: the actuality of asbestos exposure and the evaluation of the related risk; the diagnosis of the asbestos related diseases; the shape of the risk functions (namely about mesotheliomas); the causal relationship between exposure and disease; the medical surveillance of the workers currently and previously exposed. The scientific literature doesn't acknowledge the idea that nowadays in Italy the frequency of pleural mesotheliomas deriving from environmental asbestos from outdoor sources exposures is really a relevant item. Inside the SIML PPA the chapter concerning industrial hygiene and environmental monitoring themes shows inaccuracies and deficiencies, so resulting of scarce utility for the CPs that should be called for a more cooperative role in front of the employers. The arguments of the diagnosis of the asbestos related diseases is developed with an undue emphasis upon the differential histological diagnosis of asbestosis and, especially, of pleural mesothelioma: nosographic aspects that hardly are posed to the attention of the CP. A similar emphasis is posed towards the shape of the risk function for pleural mesothelioma, a theme absent from the current practice of the CP such as of other occupational practitioners. In conclusion, next to themes of undoubted interest for the PC, the SIML PPA dwells on the scrutiny of some topics representing critical elements of the current contrast between consultants and valuers in the context of criminal prosecutions: subjects having forensic relevance but far from the "application actuality" for the CP invoked in the PPA. A greater transparency, last but not least, was to have been posed, inside the SIML PPA, in the disclosure of the conflict of interests (COIs) of some Authors, declaring their consultancy in favour of companies.

The imbalance between the prevalence of patients with acute respiratory failure (ARF) and acute-on-chronic respiratory failure (ACRF) and the number of Intensive Care Unit (ICU) beds requires new solutions. The increasing use of non-invasive respiratory tools to support patients at earlier stages of ARF and the increased expertise of non-ICU clinicians in other types of supportive care have led to the development of adult Pulmonary Intensive Care Units (PICU) and Pulmonary Intermediate Care Units (PIMCU). As in other European countries, Italian PICUs and PIMCUs provide an intermediate level of care as the setting designed for managing ARF patients without severe non-pulmonary dysfunction. The PICUs and PIMCUs may also act as step-down units for weaning patients from prolonged mechanical ventilation, and for discharging patients still requiring ventilatory support at home. These units may play an important role in the on-going coronavirus disease 2019 (COVID-19) pandemic. This position paper promoted by the Italian Thoracic Society (ITS-AIPO) describes the models, facilities, staff, equipment and operating methods of PICUs and PIMCUs. [ABSTRACT FROM AUTHOR]

Managing a patient suffering from a chronic disease requires a multidisciplinary team that can take care of them beyond the simple coordination of various specialties. In this context, a central role in the treatment of chronic heart disease is the continuity of care that should promote organic integration among different hospital departments, hospital and community. This position paper of the Italian Association of Hospital Cardiologists (ANMCO) aims at defining the general principles to inspire care for complex cardiac patients at different phases of the disease. A multidisciplinary integrated holistic approach uses analytical tools able to understand the elements that characterize complexity and therefore suggest appropriate management strategies: (i) care pathways aimed at optimizing treatments; (ii) care pathways in intensive care and ward in a multidisciplinary perspective; (iii) integration of social and health needs; (iv) nursing role in the context of continuity of outpatient, community and home care; (v) promotion of educational interventions.

La regió més oriental d’Ucraïna, el Donbass, viu des de fa vuit anys una sagnant guerra en què Rússia s’ha vist directament involucrada. A més, la regió ha estat objecte de la propaganda russa, que l’ha utilitzat com un dels principals motius per justificar la seva intervenció militar sobre Ucraïna, el febrer de 2022. Tots els bàndols implicats en aquest conflicte argumenten que estan protegint els interessos i els desitjos dels seus habitants. Però aquests interessos i desitjos, a més de ser sovint manipulats, han sofert moltes modificacions i pressions després d’una guerra tan llarga, que entre altres coses ha fet que prop de la meitat dels habitants hagin abandonat la regió, i la resta es vegi sota una pressió militar, política i mediàtica constant. Aquest article intenta ser una anàlisi i una reflexió sobre l’autèntica voluntat dels habitants del Donbass, com també de la manipulació que estan sofrint.