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Abstract—SARS-CoV-2, a Coronaviridae virus related to angiotensin-converting enzyme 2 (ACE2), is the virus that causes the COVID-19 pandemic. Diabetes mellitus is a condition that is reported to have a connection with the emergence of COVID-19. A diabetic patient has a higher risk of infection compared to other nondiabetic patients. In addition, some reports showed the possibility of infection that can stimulate diabetes in an individual without a hyperglycemia history. COVID-19 was also found to show a hyperglycemic conditions that may affect mortality. Therefore, a proper monitoring as well as management of glucose level is needed for COVID-19 patients regardless of their diabetes status, to minimize the risk of mortality and development of diabetes. The possibility of diabetes mellitus induced by COVID-19 infection is investigated in this paper, as well as the monitoring of COVID-19 patients with hyperglycemic conditions. Further investigation might be needed to confirm the relationship between COVID-19 and diabetes mellitus type 1. Keywords: diabetes mellitus type 1, sars-cov-2, insulin Abstrak—SARS-CoV-2, virus Coronaviridae yang berkaitan dengan enzim pengubah angiotensin 2 (ACE2), adalah virus yang menyebabkan pandemi COVID-19. Diabetes mellitus adalah suatu kondisi yang diyakini memiliki hubungan dengan adanya COVID-19. Pasien dengan diabetes memiliki risiko infeksi yang tinggi dibandingkan dengan pasien nondiabetes lainnya. Meskipun demikian, beberapa laporan menunjukkan kemungkinan infeksi yang dapat merangsang diabetes pada individu tanpa riwayat hiperglikemia sebelumnya. COVID-19 juga ditemukan menunjukkan kondisi hiperglikemik yang dapat menyebabkan angka kematian yang cukup signifikan. Oleh karena itu, diperlukan pemantauan serta pengelolaan kadar glukosa yang tepat untuk pasien COVID-19. Kemungkinan diabetes mellitus yang disebabkan oleh infeksi COVID-19 akan diselidiki dalam makalah ini, serta pemantauan pasien COVID-19 dengan kondisi hiperglikemik. Penelitian lebih lanjut mungkin diperlukan untuk mengetahui hubungan antara COVID-19 dan diabetes melitus tipe 1. Kata Kunci: diabetes mellitus tipe 1, sars-cov-2, insulin

Diabetes Mellitus type 2 is the 7th world of death problem with the 95% proportion rate. Hypertension has also a correlation with this condition. The mortality of cardiovascular is 2-3 times over from diabetics with hypertension than diabetics with normotension which caused by lipid and aciduric disturbations. This study was conducted using cross-sectional design. Twenty-five sample of diabetics normotension and 25 sample of diabetics patient along with hypertension in Ajibarang Hospital District Banyumas and comply with inclusion-exclusion criteria were taken suing consecutive sampling. Data from the cholesterol and triglyceride total test were collected and analyzed with Mann-Whitney test. Additionally, HDL cholesterol and LDL was analyzed using T-Test. This Study showed that average total cholesterol from diabetics along with hypertension patients was in a range of 185.16 ± 36.59 and Diabetics patient without hypertension was 196.76 ± 44.62 (p = 0,503). Besides, the average rate of triglyceride level on diabetics patient with hypertension was 181.76 ±72.68 and diabetics patient along without hypertension was 180.28 ± 125.75 (p=0,367). The average rate of HDL cholesterol level on diabetics patient with hypertension was 39.12 ± 11.07 and diabetics patient along without hypertension was 42.37 ± 14.98 (p = 0,387). In addition, Average rate of LDL level on diabetics patient with hypertension was 112.57 ± 24.77 and diabetics patient along without hypertension was 118.33 ± 37.41 (p = 0,524). The average rate of uric acid on diabetics patient with hypertension was 6,120 ± 1,45 and diabetics patient along without hypertension was 5,768 ± 2,45 (p=0,200). As a conclusion, there is no difference with total cholesterol, triglyceride, HDL, LDL cholesterol, and uric acid significant from diabetics patient with or without hypertension in Ajibarang Hospital District Banyumas in 2016.