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Your search keyword '"Xiao-jing An"' showing total 12 results
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12 results on '"Xiao-jing An"'

1. Crystal structure of 1,1′-bis(diphenylphosphino)ferrocene-(1,1′-bis(diphenylphosphino)ferrocene-κ2P,P′)-(O-isobutyl sulfurodithioito-κ2S,S′)copper(I), C39H37CuFeOP2S2

Author

Li, Zhuang-yu, Liu, Xiao-jing, Liu, E., Jian, Fang-fang, and Liang, Tongling

Abstract

C39H37CuFeOP2S2, triclinic, P1̄ (no. 2), a = 9.6132(10) Å, b = 11.5667(12) Å, c = 16.8739(18) Å, α = 99.732(2)°, β = 96.342(2)°, γ = 93.446(2)°, V = 1832.0(3) Å3, Z = 2, Rgt(F) = 0.0455, wRref(F2) = 0.1212, T = 293.0 K. [ABSTRACT FROM AUTHOR]

Published
2020
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2. Crystal structure of bis(2,3-diphenyltetrazolidine-5-thione-κ1S)-(nitrato-κ1O)-(nitrato-κ2O,O′)lead(II), C26H20N10O6S2Pb.

Author

Li, Zhuang-yu, Liu, E, Liu, Xiao-jing, and Jian, Fang-fang

Abstract

Copyright of Zeitschrift für Kristallographie / New Crystal Structures is the property of De Gruyter and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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3. Crystal structure of bis(N,2-bis(4-ethoxybenzylidene)hydrazine-1-carbohydrazonothioato-κ2N,S)nickel(II) — N,N-dimethylformamide (1/2), C44H56N10S2O6Ni.

Author

Li, Zhuang-Yu, Liu, E., Liu, Xiao-Jing, Jian, Fang-Fang, and Liang, Tong-ling

Abstract

Copyright of Zeitschrift für Kristallographie / New Crystal Structures is the property of De Gruyter and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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4. The crystal structure of a matrine derivative, 13-(methylamine-1-yl) carbodithioate matrine, C17H27N3OS2.

Author

Hui-Qing, He, Fang-Yun, Dong, Han-Hui, Zhang, Jing-Min, Ye, Chun-Can, Tan, Xu-Hong, Jiang, Zi-Zhao, Zheng, Xiao-Jing, Lv, and Xing-An, Cheng

Abstract

Copyright of Zeitschrift für Kristallographie / New Crystal Structures is the property of De Gruyter and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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5. Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice

Author

Siegfried Alberti, Alfred Nordheim, Lukas von Tobel, Matthias Schäfer, Sabine Werner, Daniel Hohl, Xiao-Jing Wang, Heidi Koegel, Elisabeth Kremmer, Cornelia Mauch, Wilhelm Bloch, and Hans-Dietmar Beer

Subjects
Keratinocytes, Serum Response Factor, Pathology, medicine.medical_specialty, Cellular differentiation, Down-Regulation, Mice, Transgenic, Inflammation, Biology, Skin Diseases, Pathogenesis, Mice, transcription factor srf, gene-expression, actin dynamics, lim-kinase, mouse model, psoriasis, epidermis, integrin, system, differentiation, Cell Movement, Pregnancy, Psoriasis, Serum response factor, Cell Adhesion, medicine, Animals, Humans, RNA, Small Interfering, Cell adhesion, Cells, Cultured, Cell Proliferation, DNA Primers, Skin, Wound Healing, Base Sequence, integumentary system, Cell Differentiation, Desmosomes, General Medicine, medicine.disease, Actin cytoskeleton, Actins, Mice, Mutant Strains, Cell biology, Female, medicine.symptom, Wound healing, Research Article
Abstract

The transcription factor serum response factor (SRF) plays a crucial role in the development of several organs. However, its role in the skin has not been explored. Here, we show that keratinocytes in normal human and mouse skin expressed high levels of SRF but that SRF expression was strongly downregulated in the hyperproliferative epidermis of wounded and psoriatic skin. Keratinocyte-specific deletion within the mouse SRF locus during embryonic development caused edema and skin blistering, and all animals died in utero. Postnatal loss of mouse SRF in keratinocytes resulted in the development of psoriasis-like skin lesions. These lesions were characterized by inflammation, hyperproliferation, and abnormal differentiation of keratinocytes as well as by disruption of the actin cytoskeleton. Ultrastructural analysis revealed markedly reduced cell-cell and cell-matrix contacts and loss of cell compaction in all epidermal layers. siRNA-mediated knockdown of SRF in primary human keratinocytes revealed that the cytoskeletal abnormalities and adhesion defects were a direct consequence of the loss of SRF. In contrast, the hyperproliferation observed in vivo was an indirect effect that was most likely a consequence of the inflammation. These results reveal that loss of SRF disrupts epidermal homeostasis and strongly suggest its involvement in the pathogenesis of hyperproliferative skin diseases, including psoriasis.

Published
2009

6. The crystal structure of catena-poly[(μ2-2-((3-bromo-2-oxidobenzylidene)amino)acetato-κ4O,N,O′:O′′)-(dimethylformamide-κ1O)]zinc(II), C12H13N2O4BrZn

Author

Xi-Shi, Tai, Xiao-Jing, Zhou, Li-Li, Liu, Shu-Hua, Cao, and Li-Hua, Wang

Abstract

C12H13N2O4BrZn, monoclinic, P21/n (no. 14), a = 12.0182(12) Å, b = 6.9735(7) Å, c = 16.2510(14) Å, β = 93.572(9)°, V = 1359.3(2) Å3, Z = 4, Rgt(F) = 0.0279, wRref(F2) = 0.0613, T = 293(2) K. [ABSTRACT FROM AUTHOR]

Published
2020
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8. Crystal structure of diisopropyl 2,5-dihydroxycyclohexa-1,4-diene-1,4-dicarboxylate, C14H20O6.

Author

Li, Zhuang-Yu, Liu, E., Liu, Xiao-Jing, and Jian, Fang-Fang

Abstract

Copyright of Zeitschrift für Kristallographie / New Crystal Structures is the property of De Gruyter and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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9. Crystal structure of diisobutyl 2,5-dihydroxycyclohexa-1,4-diene-1,4-dicarboxylate, C16H24O6.

Author

Li, Zhuang-Yu, Liu, E., Liu, Xiao-Jing, and Jian, Fang-Fang

Abstract

Copyright of Zeitschrift für Kristallographie / New Crystal Structures is the property of De Gruyter and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020
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12. The crystal structure of a matrine derivative, 13-(methylamine-1-yl) carbodithioate matrine, C17H27N3OS2.

Author

Hui-Qing, He, Fang-Yun, Dong, Han-Hui, Zhang, Jing-Min, Ye, Chun-Can, Tan, Xu-Hong, Jiang, Zi-Zhao, Zheng, Xiao-Jing, Lv, and Xing-An, Cheng

Abstract

C17H27N3OS2, monoclinic, P21 (no. 4), a = 8.8052(10) Å, b = 10.8860(10) Å, c = 18.6705(2) Å, β = 99.2730(10)°, V = 1766.24(3) Å3, Z = 4, Rgt(F) = 0.0298, wRref(F2) = 0.0802, T = 100.00(10) K. [ABSTRACT FROM AUTHOR]

Published
2020
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