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1. Antitumor Cyclic Hexapeptides from Rubia Plants: History, Chemistry, and Mechanism (2005–2011)

Author

Si Meng Zhao, Bin Kuang, Jun Ting Fan, He Yan, Wen Yan Xu, and Ning Hua Tan

Subjects
Antitumor, Cyclic hexapeptides, Rubia, Rubiaceae-type cyclopeptides, Chemistry, QD1-999
Abstract

Rubiaceae-type cyclopeptides (RAs), cyclic hexapeptides from Rubia plants, have shown potential antitumor activity in vitro and in vivo. Based on the review about plant cyclopeptides (Chem. Rev., 2006, 106: 840), this mini-review will highlight new progress on the discovery, synthesis, and mechanism of RAs isolated during 2005 to 2011, covering recent work in our group.

Published
2011
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