1. [Periorbital erythematous plaques and papules in an HIV-positive patient : A case report].
- Author
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Szczęch J, Samotij D, Sawińska E, and Reich A
- Subjects
- Adult, Antiretroviral Therapy, Highly Active methods, Glucocorticoids administration & dosage, Granuloma diagnosis, Granuloma drug therapy, HIV Infections drug therapy, HIV Infections immunology, Humans, Immune Reconstitution Inflammatory Syndrome, Male, Sarcoidosis complications, Sarcoidosis drug therapy, Granuloma complications, HIV Infections complications, Hepatitis C complications, Sarcoidosis diagnosis
- Abstract
Prior to the introduction of antiretroviral therapy, the concomitant occurrence of sarcoidosis and human immunodeficiency virus (HIV) was extremely rare. Today, an increased prevalence of sarcoidosis as a result of immune reconstitution syndrome (IRIS) is observed in HIV patients. A 37-year-old male patient that was co-infected with HIV and hepatitis C had a 6‑month history of gradually progressive asymptomatic periorbital erythematous plaques and papules. Routine clinical examinations were normal. Skin punch biopsy taken from the upper portion of the right cheek showed several non-caseating dermal granulomas with multinucleated giant cells, enabling unequivocal histological diagnosis. Based on the clinical picture and histological findings, the patient was diagnosed with cutaneous sarcoidosis. This case study underlines the change in possible rheumatological and dermatological comorbities in HIV-positive patients treated with highly active antiretroviral therapy. Therefore, physicians treating HIV infections should be familiar with the definition of IRIS.
- Published
- 2020
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