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The article describes the groundbreaking new ingredient Shiloxome ™, developed by Provital, which counteracts signs of aging and protects the skin in a multi-omic way. The ingredient is derived from the endophytic yeast Kwoniella mangroviensis and acts as a protective shield for the skin. Provital has developed a technology that allows them to isolate endophytic strains and investigate their bioactivity. The first developed ingredient, Shiloxome ™, comes from the endophytic yeast species Kwoniella mangroviensis found in the bark of the cork oak. This ingredient protects the skin and gives it the ability to adapt and survive. Provital has also conducted a study on the effectiveness of the ingredient, which has shown that it protects the skin from environmental stressors and improves the integrity of the skin barrier. The active ingredient has a positive effect on the overall chain length of the lipidome and strengthens the permeability barrier of the skin. Signal pathways related to the structure and organization of the extracellular matrix have been identified. The active ingredient also has a significant effect on the remodeling and overall condition of the skin structure and function. An improvement in elastin and collagen I levels has been observed. The results show that the active ingredient strengthens the lipid barrier and contributes to the restoration of youthful and healthy skin. The article describes a new active ingredient called Shiloxome ™, developed by Provital. The active ingredient is based on endophytes and is produced using the Triplobiome ™ technology. Shiloxome ™ offers benefits in the fight against skin aging and restructures the skin barrier. It has been shown that the active ingredient reduces lipid oxidation and provides comprehensive skin protection. Shiloxome ™ is recommended as a powerful ally for resilient, youthful skin. [Extracted from the article]

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