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Deep brain stimulation is an established and evidence-based therapeutic option for the treatment of advanced Parkinson's disease. Main indication and inclusion criteria are the presence of idiopathic Parkinsonism with motor fluctuations and / or dyskinesias and / or with medication refractory tremor, a significant improvement of akinesia / rigidity in response to dopaminergic medication, the absence of relevant cognitive deficits and other significant comorbidities. DBS neurosurgery has a low risk of complications. The clinical programming should follow an established monopolar review algorithm. Regular follow-up visits are required for stimulation monitoring., Competing Interests: Erklärung zu finanziellen InteressenForschungsförderung erhalten: nein; Honorar / geldwerten Vorteil für Referententätigkeit erhalten: nein; Bezahlter Berater / interner Schulungsreferent / Gehaltsempfänger: nein; Patent / Geschäftsanteile / Aktien (Autor / Partner, Ehepartner, Kinder) an im Bereich der Medizin aktiven Firma: nein; Patent /Geschäftsanteile / Aktien (Autor / Partner, Ehepartner, Kinder) an zu Sponsoren dieser Fortbildung bzw. durch die Fortbildung in ihren Geschäftsinteressen berührten Firma: nein.Erklärung zu nichtfinanziellen InteressenDie Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)