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Unlabelled: This re-evaluation of a double-blind placebo-controlled therapeutic study of the combined sabal-urtica preparation PRO 160/120 investigates the changes in the irritative symptoms of benign prostatic hyperplasia (BPH) under the test substance in comparison with placebo. It was found that, over the study period of 24 weeks, the micturition symptoms frequency and urgency were statistically significantly improved under the well-tolerated PRO 160/120 in comparison with placebo. The patient's quality of life was also significantly better under PRO 160/120 in comparison with placebo., Conclusion: The often distressing symptoms of BPH can be effectively ameliorated already after only a few weeks of treatment with the sabal-urtica preparation PRO 160/120. In particular those patients with the stigmatizing symptoms urinary urgency and frequency benefit from such treatment.

In the present paper, the use of the combination preparation sulfamoxol/trimethoprim (CN 3123, Nevin [Grünenthal], Supristol [Nordmark]) in urinary tract infections is reported. This preparation was used in 165 patients of both sexes and all ages. The initial dose was 2 tablets followed by a maintenance dose of 1 tablet every 12 hours for a treatment lasting 10 days on the average. The preparation led to asepsis in 69% of the patients with chronic urinary tract infections if the organisms were sensitive in vitro. In asymptomatical urinary tract infections complicated by fistula and transurethral indwelling catheters, on the other hand, elimination of organisms was only attained in 46%. In our opinion, antibiotic therapy is not indicated in these patients only after taking off the indwelling catheter.

Fifty in-patients suffering from chronic urinary tract infections with underlying urological diseases received the oral Carbenicillin preparation Indanyl Carbenicillin (short term Carindacillin) for 10 days in a dosage of 1 g q.i.d. The therapy results were objectified by blood and urine tests performed prior to and after treatment. Indanyl Carbenicillin led to a sterile urine in nearly 60% of the patients; in about 85% of the cases the primary organism was eliminated. The drug was particularly active against difficult organisms such as Proteus, Klebsiella and Pseudomonas. The results obtained in this study are somewhat surprising as the dosage used produces bactericidal levels of the active substance only in the cavity system of the efferent urinary tract but not in the tissue. No effect on blood picture or liver function was observed. Side effects occurred in 8 patients, they disappeared with continued therapy or after discontinuation of the drug. Considering the good efficacy observed in this study and because of the possibility of oral administration, Indanyl Carbenicillin appears to be suitable also for out-patient treatment of chronic urinary tract infections due to difficult urological germs.

We report on late results of 100 risk patients, who were operated by cryosurgical technique because of bladder neck obstructions. Detailed representation of complications. The primary mortality was 5%. Controls after one year showed good functional results on 80% of the patients. 60% of the patients had sterile urine, whereas only 17% of the male patients had no infection before the operation. As to the anatomical results we could talk of a cryoprostatectomy in 25% of the cases. Because of a 20% failure cryosurgery remains a palliative operation, which can only be carried out on risk patients. Because of little hemorrhagic diathesis and the possibility to perform this operation under local anesthesia cryosurgical operations on the other hand are suitable for patients, who cannot be anesthetised. Otherwise these patients had needed a permanent catheter. We prefer shorter freezing times of 3--4 min. Essentially we could show the same functional results as other authors, who preferred longer freezing times, until they reached a certain temperature in the prostatic capsule. By shorter freezing times on the contrary we could avoid secondary transurethral resections of larger necroses. New disturbed micturition after cryosurgical treatment of the prostate is unusual. The question of a later recidivation is of secondary importance because of the primary high morbidity rate of the selected number of cases.