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5. [Cerebral contrast medium extravasation after coronary angioplasty].

Author

Foltys H, Krings T, and Block F

Subjects
Aged, Aged, 80 and over, Aphasia chemically induced, Aphasia diagnostic imaging, Brain Edema diagnostic imaging, Contrast Media pharmacokinetics, Dominance, Cerebral drug effects, Female, Hemiplegia chemically induced, Hemiplegia diagnostic imaging, Humans, Iohexol pharmacokinetics, Metabolic Clearance Rate physiology, Neurologic Examination drug effects, Tomography, X-Ray Computed, Blood-Brain Barrier drug effects, Brain Edema chemically induced, Contrast Media adverse effects, Coronary Angiography adverse effects, Extravasation of Diagnostic and Therapeutic Materials diagnostic imaging, Iohexol adverse effects, Iohexol analogs & derivatives
Abstract

We report on an 82-year-old woman who suffered a sudden loss of consciousness, right-sided hemiparesis, and aphasia during a coronary angiographic procedure. Computed tomography (CT) of the brain performed immediately revealed an edema and extravascularly localized contrast media in the left hemisphere. Within 6 h, neurological symptoms had disappeared, and a second CT after 48 h revealed normal results. Usually, extravasation of contrast media affects the posterior circulation with cortical blindness. This case demonstrates that contrast media may affect the blood-brain barrier also outside the posterior circulation. If neurological symptoms occur during angiography, contrast media extravasation must be distinguished from embolism or vasospasm induced by the angiographic procedure.

Published
2003
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