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Copyright of Der Ophthalmologe is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Der Ophthalmologe is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Der Ophthalmologe is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Hordeolum and chalazion are the most frequent inflammatory eyelid tumors. They can occur in association with underlying diseases causing Meibomian gland dysfunction and/or chronic blepharitis. Due to the typical morphological features and clinical course, the diagnosis can mostly be clinically established. The majority of these lesions resolve spontaneously over time. In some instances, surgical intervention is unavoidable. In persistent, recurrent or clinically atypical cases malignant tumors must be excluded as a differential diagnosis by excisional biopsy and histopathological assessment., (© 2021. Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)

Das selten diagnostizierte Merkelzeil Karzinom gilt seit 1972 als eigenständiger maligner Hauttumor, welcher im Bereich des gesamten Integuments vorkommt und im Periorbitalbereich vorwiegend am Oberlid lokalisiert ist. Seine morphologischen Eigenschaften mit angiomatös-nodulärem Aspekt führen bisweilen zur Fehldiagnose Chalazion mit daraus resultierend verzögertem Beginn der suffizienten radikalchirurgischen Therapie. Im Einklang mit dem derzeit üblichen internationalen Vorgehen wurde der Tumor unter intraoperativer Gefrierschnittkontrolle großzügig im Gesunden exzidiert. Die Diagnosestellung erfolgte durchwegs histologisch und immunhistochemisch. Wegen der Größe des Tumors konnte in einem Fall mit orbitaler Beteiligung eine Enukleation nicht unterbleiben. Die Defekte wurden plastisch gedeckt, in einem Fall mit nachfolgender Tarsusverlängerungsplastik. Es wird über 3 Patientinnen mit histologisch und immunhistochemisch gesichertem Merkelzell Karzinom berichtet. Das Durchschnittsalter betrug 80,3 ± 7,23 a. In keinem der Fälle wurde ein Rezidiv beobachtet. Die derzeitige durchschnittliche Überlebensdauer der drei Fälle beträgt 4 ± 1,7 a. Es erfolgt eine Falldarstellung und kurze Literaturübersicht. Merkelcell-Carcinoma was first diagnosed in 1972 and represents an unique dermal tumor, which is mainly found in older patients all over the body. In the periorbital region it is mainly localized in the upper eyelid region. The morphological characteristics show signs of an angiomatous nodular tumor, which often leads to the misdiagnosis chalacion or pyogenic granuloma resulting in a delayed radical surgical therapy. Histology: these cells were first described by Merkel in 1875: small regular cells, being grouped in chords with a large nucleus and rare cytoplasm. Neurosecretoric granula and intermediate filaments are also characteristic for the Merkelcell Carcinoma, as well as its lymphomatous aspect. We report on three patients with a histologically and immunhistochemically diagnosed Merkelcell Carcinoma. Following radical surgical therapy with frozen sections we could not avoid enucleation in one case with orbital infiltration. We present the three case reports with a short review on the recent references. [ABSTRACT FROM AUTHOR]

Corneal changes associated with eyelid disease are frequent and can considerably complicate the course of the disease. They can manifest as refraction anomalies, corneal degeneration, ocular surface disease, corneal infiltrates, corneal vascularization and corneal ulceration up to corneal perforation. Pathophysiologically relevant are compressive forces, exposure, trichiasis and distichiasis, eye rubbing, inflammation and infection. A multitude of eyelid diseases is associated with diseases of the cornea including eyelid malposition, eyelid tumors, eyelid infections, allergic eyelid dermatitis, blepharitis, meibomitis, and Meibomian gland disease.

Copyright of Der Ophthalmologe is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)