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Starting in 2020, the global health system faced unprecedent challenges due to the coronavirus disease 2019 (COVID-19) pandemic and the consequences are still felt. All the more fascinating and of particular importance for health policy was the development of potent vaccines within about one year by several research groups after the first reports of COVID-19 infections. To date, three types of COVID-19 vaccines are available, i.e., messenger RNA-based vaccines, adenoviral vector vaccines, and inactivated whole-virus vaccines. We report a woman who developed reddish, partially urticarial skin lesions on her right arm and flank shortly after the first dose with the corona vaccination from AstraZeneca/Oxford (ChAdOx1). The lesions were transient, however reoccurred in loco and at other locations over several days. The clinical presentation was unusual and was correctly assigned due to the clinical course., (© 2023. The Author(s).)

Objective: The aim of this study was to investigate the effect of cigarette smoking on the failure rates of orthodontic miniscrews., Patients and Methods: Our cohort consisted of 88 patients with a total of 110 orthodontic miniscrews. Based on their smoking habits, the patients were divided into three groups: the light smokers (< or = 10 cigarettes/day), heavy smokers (> 10 cigarettes/ day), and non-smokers. The light-smoker group consisted of 14 patients with 18 orthodontic miniscrews, and there were 15 patients with 19 miniscrews among the heavy smokers. The nonsmoker group contained 59 patients with a total of 73 miniscrews., Results: The overall failure rate was 18.2% (n = 20). Heavy smokers revealed a significantly higher failure rate than light smokers (p = 0.005) or non-smokers (p < 0.001). No significant differences were observed between non-smokers and light smokers. Miniscrews in the heavy smoker group exhibited a significantly higher failure rate during the first 4 months after insertion than did the miniscrews in the light smokers (p = 0.008) or non-smokers (p < 0.001)., Conclusion: Our results suggest that heavy smoking has a detrimental effect on the success rates of orthodontic miniscrews.