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1. [Long-term prognosis of drug and surgery treated patients with acquired aortic valve diseases: survival statistics and multivariate Cox regression analysis].

Author

Schwarz F, Ehrmann J, Olschewski M, Scheurlen H, Manthey J, Storch HH, Saggau W, and Kübler W

Subjects
Anti-Bacterial Agents therapeutic use, Aortic Valve Insufficiency drug therapy, Aortic Valve Stenosis drug therapy, Bioprosthesis, Digitalis Glycosides therapeutic use, Diuretics therapeutic use, Female, Hemodynamics drug effects, Humans, Male, Middle Aged, Postoperative Complications mortality, Prognosis, Regression Analysis, Aortic Valve Insufficiency surgery, Aortic Valve Stenosis surgery, Heart Valve Prosthesis
Abstract

Data of 417 patients with advanced chronic aortic valve disease were retrospectively analyzed using a life table and Cox regression analysis. Aortic valve replacement was recommended to all patients based on clinical and hemodynamic findings. While most patients underwent prosthetic aortic valve replacement (n = 349), a minority of patients was treated medically (n = 68). Prognosis was better (p less than 0.01 in the Cox model) in surgically treated as compared to medically treated patients with aortic stenosis (4-year survival rate 82 versus 44%). In patients with aortic insufficiency no significant difference of long-term prognosis was found between surgically and medically treated patients.

Published
1985

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