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Your search keyword '"DNA, Bacterial drug effects"' showing total 3 results
Start Over Descriptor "DNA, Bacterial drug effects" Language german
3 results on '"DNA, Bacterial drug effects"'

2. [Inhibition of gyrase by 4-quinolones: effect on the structure of DNA].

Author

Weisser J and Wiedemann B

Subjects
Conjugation, Genetic, DNA Replication drug effects, Drug Resistance, Microbial, Plasmids, Transcription, Genetic, Anti-Infective Agents pharmacology, DNA, Bacterial drug effects, Quinolines pharmacology, Topoisomerase II Inhibitors
Abstract

DNA gyrase is an essential enzyme in bacterial metabolism. Its function is the introduction of negative supercoils into DNA. These favour the unwinding of certain parts of DNA und thus are likely to facilitate processes like replication and transcription. Inhibition of DNA gyrase by quinolones and possible effects on the structure of DNA are reviewed.

Published
1986
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3. [Experimental research on the genotoxicity of various root canal antiseptics in the SOS chromotest].

Author

Klimm W, Janz S, and Gabert A

Subjects
Mutagenicity Tests instrumentation, Mutagenicity Tests methods, Anti-Infective Agents, Local, DNA Repair drug effects, DNA, Bacterial drug effects, Escherichia coli drug effects, Root Canal Irrigants toxicity, SOS Response, Genetics drug effects
Abstract

The genotoxicity of the endodontic antiseptics chlorhexidine digluconate, chloramine and sodium hypochlorite was determined by SOS chromotest using Bioscreen Analyzer Systems (Labsystem OY). All antiseptics did not show a genotoxic effect. Chlorhexidine digluconate was the most efficient antimicrobial agent against E. coli PQ 37.

Published
1989

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