12,380 results on '"Cross-Sectional Studies"'
Search Results
2. Ärztlich assistierte Selbsttötung: Erfahrungen und Bewertungen von Mitgliedern der Deutschen Gesellschaft für Hämatologie und Medizinische Onkologie
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Schildmann, Jan, Junghanß, Christian, Oldenburg, Michael, Schuler, Ulrich, Wörmann, Bernhard, Trümper, Lorenz, and Winkler, Eva
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- 2024
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3. [Drug-induced QT interval prolongation. Evaluating the prevalence of potentially fatal cardiac arrhythmias in a specific cohort of patients].
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Groth O, Roider G, and Graw M
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- Humans, Male, Female, Middle Aged, Adult, Aged, Cohort Studies, Cross-Sectional Studies, Electrocardiography, Cause of Death, Germany, Aged, 80 and over, Risk Factors, Death, Sudden, Cardiac etiology, Death, Sudden, Cardiac epidemiology, Young Adult, Arrhythmias, Cardiac chemically induced, Arrhythmias, Cardiac epidemiology, Arrhythmias, Cardiac diagnosis, Autopsy, Adolescent, Long QT Syndrome chemically induced, Long QT Syndrome epidemiology, Long QT Syndrome diagnosis, Long QT Syndrome mortality, Antipsychotic Agents adverse effects
- Abstract
Some drugs prolong the QT interval, which can be fatal in the presence of other risk factors. In the 3040 forensic autopsy cases that underwent toxicological analysis over the past five years, in which no certain cause of death could be identified, at least one drug with QT interval prolonging potential was detected in 188 individuals (6%). Risk factors for cardiac events, incl. a history of drug and/or alcohol abuse (45%), pathological cardiovascular changes (66%), and more than one QT-prolonging drug (64%) pointed toward fatal arrhythmic events resulting from the drug, of which antipsychotics were the most prevalent in our cohort., (© 2024. Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)
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- 2024
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4. [Patients with Diabetes Mellitus and Comorbid Mental Disorders - Is there a Psychotherapeutic Undertreatment? - Results of the DiMPS Study].
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Röhrig B, Petrak F, Bartel A, Hagena V, Dieris-Hirche J, Meier JM, and Herpertz S
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- Humans, Male, Female, Middle Aged, Germany epidemiology, Adult, Aged, Cross-Sectional Studies, Longitudinal Studies, Diabetes Mellitus, Type 1 complications, Diabetes Mellitus, Type 1 therapy, Diabetes Mellitus, Type 1 psychology, Diabetes Mellitus, Type 1 epidemiology, Undertreatment, Mental Disorders therapy, Mental Disorders epidemiology, Mental Disorders psychology, Psychotherapy statistics & numerical data, Comorbidity, Diabetes Mellitus, Type 2 therapy, Diabetes Mellitus, Type 2 complications, Diabetes Mellitus, Type 2 psychology, Diabetes Mellitus, Type 2 epidemiology
- Abstract
Aim of the Study: Diabetes mellitus is associated with an increased likelihood of mental disorders, especially depression. Despite a frequently postulated underprovision, the actual need for psychotherapeutic treatment in this patient group has hardly been investigated. The aim of this study is to analyze the care situation of diabetes patients with mental comorbidities in Germany., Methods: 240 consecutively treated patients with type 1 or type 2 diabetes were examined cross-sectionally and longitudinally in a tertiary diabetological center. After a screening and diagnostic examination, 94 patients with comorbid mental disorders were included in the study. Patients then decided on the treatment of their mental disorder according to a standardized shared decision-making process. At the 6-month follow-up, 77 of the 94 patients (81.9%) provided information about the realization of their treatment decision and the obstacles they encountered., Results: 39.2% of patients with diabetes had a mental disorder. Of these, 44.2% were already receiving psychotherapy or medication. After six months, 46.8% were able to implement their treatment decision. Only 7.1% did not receive any treatment despite their efforts. The 6-month follow-up showed a significant reduction in diabetes-related distress (PAID; p<0.05) and an increase in psychological well-being in all subgroups, regardless of treatment initiation (WHO-5; p<0.05)., Discussion: Contrary to the widespread notion of a lack of access to psychotherapy for people with diabetes and mental disorders in Germany, this assumption could not be confirmed in this study., Conclusion: Equating the frequency of mental disorders with the need for psychotherapeutic and/or psychopharmacological treatment without considering the specific treatment needs and preferences of patients may lead to an overestimation of the need for care., Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)
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- 2024
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5. [Regional Variance of Rates of Involuntary Admission in Switzerland].
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Jäger M, Tuch A, Theodoridou A, Hepp U, and Stulz N
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- Humans, Switzerland, National Health Programs statistics & numerical data, Utilization Review statistics & numerical data, Cross-Sectional Studies, Urban Population statistics & numerical data, Ambulatory Care statistics & numerical data, Ambulatory Care trends, Commitment of Mentally Ill statistics & numerical data, Commitment of Mentally Ill trends, Commitment of Mentally Ill legislation & jurisprudence, Mental Disorders therapy, Mental Disorders epidemiology
- Abstract
Objective: Identification of predictors that contribute to explaining regional variance of involuntary admission (IA) in Switzerland., Methods: Multiple regression analysis including potential predictors and regional rates of IA at the level of utilisation-based care regions., Results: Authorisation to issue involuntary admission, assistance/guardianship, outpatient consultation rate in psychiatric practices, hospitalisation rate and urbanisation are significantly related to regional variation in IA rates., Conclusion: Restrictive regulation of the authority to issue IA and voluntary outpatient psychosocial and administrative support measures can contribute to a reduction in the rates of IA., Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)
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- 2024
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6. [Assisted suicide in Switzerland (part 1): Medical-ethical controversies and the dilemma of the sorcerer's apprentice].
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Güth U, Battegay E, Jox RJ, Abawi K, Weitkunat R, and Schneeberger AR
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- Switzerland, Humans, Female, Male, Aged, Mental Disorders, Dementia, Ethics, Medical, Middle Aged, Aged, 80 and over, Cross-Sectional Studies, Suicide, Assisted ethics, Suicide, Assisted legislation & jurisprudence
- Abstract
Introduction: Based on the cases in which assisted suicide (AS) has taken place in Switzerland in the context of a mental disorder or dementia, we discuss whether the slippery slope argument often brought up by opponents of assisted dying is justified. Long-term data from the Swiss Federal Statistical Office shows that while the number of cases with these «indications» is increasing (1999-2017: on average 21 cases/year vs. 2018-2022: n = 73 cases/year), the percentage share of these diseases in the total number of all AS cases has remained unchanged at around 5 %. Opponents of assisted dying believe that the slippery slope argument is already fulfilled by the fact that these cases occur at all. However, the still limited prevalence of these specific indications which still represent only a minority of assisted suicide cases over time, may be used by advocates of assisted dying to weaken the opposing viewpoint., Competing Interests: Die Autoren bestätigen, dass kein Interessenkonflikt besteht. Keiner der Autoren ist Mitglied in einer der Schweizer Sterbehilfeorganisationen., (© 2024 Aerzteverlag medinfo AG.)
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- 2024
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7. [Psychological stress and the need for stress management in veterinary studies].
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Müller R, Scholz M, Müller P, and Burger P
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- Humans, Cross-Sectional Studies, Surveys and Questionnaires, Female, COVID-19 psychology, COVID-19 epidemiology, Male, Depression psychology, Switzerland, Students psychology, Veterinarians psychology, Adult, Stress, Psychological psychology, Education, Veterinary
- Abstract
Introduction: Veterinary students suffer from increased psychological stress compared to the general public and are increasingly affected by manifest mental illnesses such as depression and anxiety disorders, as well as an increased prevalence of suicidal thoughts. Additionally, veterinary students tend to ignore signs of mental distress and do not seek support for their mental health issues. This impaired mental health is also evident in fully trained veterinarians, who, among other things, have the highest suicide rates of all medical professions. In our survey, we examined a total of 428 veterinary students at the two veterinary faculties of the Universities of Zurich and Bern. The survey was carried out across all six years of the curriculum as a cross-sectional survey using standardized questionnaires on resilience, sense of coherence and depression. In all years, the students showed increased levels of depression compared to the general public, and the salutogenic parameters of resilience and sense of coherence were also reduced. The constellation with increased depression, reduced resilience and reduced sense of coherence was particularly accentuated in the second and third year. The increased affective stress on students presents itself as a consistent condition, which - if you look at studies on fully trained veterinarians - continues into their working life together with a reduced ability to cope. The low number of participants in the higher years of study and the high number of female study participants could limit the generalizability of the results. In addition, the data was collected in spring 2021 during the COVID-19 pandemic, which may have influenced the results. Active counteracting, for example by integrating the teaching of protective behavior such as mindful self-compassion and resource-oriented behavior such as mind-body techniques, therefore appears to be recommended in the veterinary training curriculum from the first semester onwards. Various measures to support students have been introduced since 2021, such as events on learning strategies, a mentoring system and seminars on mental health.
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- 2024
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8. [Sepsis in emergency medical services : A cohort study on screening, incidence, and mortality].
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Piedmont S, Goldhahn L, Swar E, Robra BP, Fleischmann-Struzek C, Somasundaram R, and Bauer W
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- Humans, Germany, Male, Mass Screening, Female, Cohort Studies, Aged, Incidence, Middle Aged, Cross-Sectional Studies, Sepsis mortality, Sepsis diagnosis, Sepsis therapy, Emergency Medical Services
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- 2024
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9. [Ethical Attitudes and Handling in Prenatal Conflict Situations - A Survey among Obstetricians and Prenatal Diagnosticians in Germany].
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Schneider K, Müller J, Tissen-Diabaté T, and Schleußner E
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- Humans, Germany, Female, Pregnancy, Cross-Sectional Studies, Surveys and Questionnaires, Male, Adult, Conflict, Psychological, Ethics, Medical, Obstetricians, Obstetrics ethics, Attitude of Health Personnel, Prenatal Diagnosis ethics
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Objective: Various studies have shown that belonging to a professional group has an influence on ethical attitudes. The aim of this study was to assess and compare the attitudes and approaches of obstetrical specialists and prenatal diagnosticians in prenatal conflict situations., Methods: Explorative cross-sectional online survey among tertiary perinatal care centers and prenatal diagnosticians with DEGUM Level II/III in Germany. The questionnaire included questions on ethical attitudes in the perinatal context and a case presentation of a fetal hypoplastic left heart syndrome., Results: The response rate was 57.1% (310/543). 55.5% of the respondents practiced both obstetrics and prenatal diagnostics, 24.5% exclusively prenatal diagnostics, and 14.2% purely obstetrics. 27% agreed with the statement "An uncertain prognosis justifies pregnancy termination". For complex fetal malformations joint interdisciplinary counseling was advocated by 98.3%. Addressing the option of postnatal palliative treatment in a case of a hypoplastic left heart syndrome was accepted by 84.3% across all professional groups, while mentioning fetocide was more frequently cited as an option by prenatal diagnosticians than by obstetricians (57.7% vs. 34.1%)., Conclusion: Interdisciplinary prenatal parental counseling in complex fetal malformations is uniformly advocated by prenatal diagnosticians and obstetricians in Germany. However, different ethical attitudes appear among specialists groups with regard to the option of termination of pregnancy., Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)
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- 2024
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10. [Current data on rheumatological care: annual report from the National database (NDB) of the regional collaborative arthritis centres in Germany].
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Albrecht K, Thiele K, Alexander T, Aringer M, Eidner T, Henes J, Hoese G, Karberg K, Kiltz U, Krause A, Ochs W, Richter JG, Späthling-Mestekemper S, Steinmüller M, Wassenberg S, Strangfeld A, and Callhoff J
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- Germany, Humans, Female, Male, Middle Aged, Adult, Aged, Rheumatic Diseases epidemiology, Rheumatic Diseases therapy, Cross-Sectional Studies, Aged, 80 and over, Young Adult, Prevalence, Adolescent, Treatment Outcome, Arthritis, Rheumatoid epidemiology, Arthritis, Rheumatoid therapy, Antirheumatic Agents therapeutic use, Databases, Factual, Rheumatology statistics & numerical data
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In the National database (NDB) of the German regional collaborative arthritis centres, annual data on the rheumatological care of patients with inflammatory rheumatic diseases have been collected since 1993. This first annual report presents current cross-sectional data on medication and patient-reported outcomes gathered in 2022., (© 2024. The Author(s).)
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- 2024
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11. [Discharged, but where to? The Current Situation of Long Stay Patients in German Psychiatric Clinics].
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Jenderny S, Claus S, Falkai P, Heinz A, Meyer-Lindenberg A, Pogarell O, Wilms B, and Steinhart I
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- Humans, Male, Germany, Female, Middle Aged, Adult, Aged, Hospitals, Psychiatric statistics & numerical data, National Health Programs statistics & numerical data, Cross-Sectional Studies, Length of Stay statistics & numerical data, Mental Disorders therapy, Mental Disorders epidemiology, Mental Disorders psychology, Patient Discharge statistics & numerical data
- Abstract
Objective: The study analyses the number, characteristics and reasons for a length of stay of patients in German psychiatric clinics in excess of 6 months., Methods: The study was implemented in the form of a nationwide online survey, which was addressed to chief physicians of psychiatric clinics., Results: In the sample, 174 patients in 80 psychiatric clinics were identified who could not be discharged because no suitable follow-up services were available in the region. The majority of patients are male, often have an F2 diagnosis and exhibit aggressive behaviour during their hospital stay., Conclusion: To avoid inappropriate health care and prevent prolonged stays for a subgroup of mentally ill people, individual complex services should be implemented in community psychiatry., Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)
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- 2024
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12. [Pain management in German specialized outpatient palliative care : A cross-sectional study to present the current pain management of palliative patients in the home environment].
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Volberg C, Corzilius J, Maul J, Morin A, and Gschnell M
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- Cross-Sectional Studies, Humans, Germany, Ambulatory Care, Analgesics therapeutic use, Patient Care Team, Palliative Care, Pain Management methods, Home Care Services
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Background: With the help of specialized outpatient palliative care teams (German abbreviation: SAPV), seriously ill and dying patients in Germany can be adequately cared for in their home environment until the end of their lives; however, there are no uniform standards or guidelines for well-executed pain management right now., Objective: This approach serves as basic research in the field of public health research. This is intended to present which methods (use of different professional groups, use of pain medications, alternative medical treatment etc.) the individual SAPV teams use for pain management. From this it can be deduced which procedures can be considered particularly effective., Material and Methods: This cross-sectional study was conducted in May 2021. All German SAPV teams (n = 307) listed on the homepage of the German Association for Palliative Medicine (DGP) were contacted by post and invited to participate. A total of 175 teams (57%) responded to the request and were included in the evaluation. A descriptive data analysis was performed., Results: Pain management in the German outpatient care of palliative patients is based on several components. All common pain medications are used, but primarily metamizole (99.4%) as a non-opioid analgesic, morphine (98.3%) from the opiate series and pregabalin (96.6%) as a co-analgesic are mainly prescribed. If pain therapy fails, 22.5% of the SAPV teams perform palliative sedation for symptom control on a regular basis., Conclusion: This cross-sectional study is the first of its kind to provide a general overview of the treatment options for pain management in German outpatient palliative care. In comparison with international studies, the question arises as to whether uniform therapy schemes and a reduction in the medication available in the individual SAPV teams could lead to an improvement in patient care., (© 2023. The Author(s).)
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- 2024
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13. [Incontinence-associated dermatitis: a frequent and overlooked problem in older people].
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Kottner J, El Genedy-Kalyoncu M, and Dissemond J
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- Humans, Aged, Risk Factors, Cross-Sectional Studies, Dermatitis etiology, Dermatitis diagnosis, Female, Aged, 80 and over, Male, Urinary Incontinence epidemiology, Urinary Incontinence etiology, Urinary Incontinence diagnosis, Fecal Incontinence etiology
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- 2024
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14. [Healthcare quality and safety in left ventricular assist device therapy from the patient perspective: A qualitative study on relevant aspects of care].
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Levelink M and Brütt AL
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- Humans, Middle Aged, Female, Male, Aged, Adult, Cross-Sectional Studies, Germany, Patient Safety, Qualitative Research, Quality of Health Care, Patient Satisfaction, Heart Failure therapy, Self Care, Heart-Assist Devices, Aftercare
- Abstract
Introduction: Implantation of a left ventricular assist device (LVAD) requires extensive aftercare. It is largely unclear how aftercare should be designed from the patients' perspective. Implications can be developed based on an examination of the healthcare context. Its main components are mapped on five tiers in the Human Factors of Home Health Care Model by Henriksen, Joseph, and Zayas-Caban (2009). Using this model, the present study explores the patient perspective on the context of healthcare after an LVAD implantation., Methods: We employed a qualitative cross-sectional study, in which LVAD patients participated in semi-structured interviews. The transcribed interviews were analyzed using content analysis. First, relevant meaning units were identified and deductively categorized into the model. Then, categories of care-related aspects were developed inductively within each of the model tiers., Results: We interviewed 18 patients aged 33 to 78 years who had been living with the LVAD between a few weeks and more than 10 years. Twenty-eight categories related to care aspects were developed within the model tiers: 3 categories on patient characteristics (e.g., self-management skills), 3 on caregiver characteristics (e.g., professionalism), 11 healthcare-related tasks and requirements (e.g., wound management), 8 on factors of the physical environment (e.g., controllability), medical devices and technologies (e.g., carrying systems for external components), and cultural, social and community environment (e.g., interaction with peers), as well as 3 on external environmental factors (e.g., healthcare infrastructure)., Discussion: The present study represents the first investigation focusing on aspects of the healthcare context influencing healthcare quality and safety from the perspective of LVAD patients in Germany. LVAD aftercare covers a broad and complex range of tasks. For this, patients, caregivers and healthcare professionals need specific knowledge, which is lacking in various respects. In the first place, this is compensated by the patients' own initiative and the personal care provided by the VAD outpatient clinics., Conclusion: Three key recommendations to optimize aftercare from the patient perspective are derived: Patients would benefit from a more flexible and decentralized aftercare concept, to which telemedicine could contribute. LVAD-specific expertise among general healthcare providers is perceived as insufficient by patients and could be strengthened through training and counseling services. The broad scope of tasks and the high level of responsibilities in LVAD aftercare pose challenges for patients and their families, which could be addressed through continuous information and training programs., (Copyright © 2024. Published by Elsevier GmbH.)
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- 2024
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15. [Liver diseases in the intensive care unit].
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Roedl K and Fuhrmann V
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- Humans, Liver Cirrhosis complications, Liver Cirrhosis therapy, Liver Cirrhosis diagnosis, Cross-Sectional Studies, Acute-On-Chronic Liver Failure therapy, Acute-On-Chronic Liver Failure diagnosis, Acute-On-Chronic Liver Failure mortality, Critical Care, Liver Failure, Acute therapy, Liver Failure, Acute diagnosis, Liver Failure, Acute mortality, Prognosis, Critical Illness, Intensive Care Units, Liver Diseases therapy, Liver Diseases diagnosis, Liver Diseases mortality
- Abstract
The frequency of liver diseases in the intensive care unit has increased significantly in recent years and is now observed in up to 20% of critically ill patients. The occurrence of liver disease is associated with significantly increased morbidity and mortality. Two groups of liver diseases in the intensive care unit can be distinguished. First, the group of "primary hepatic dysfunctions", which includes primary acute liver failure as well as acute-on-chronic liver failure in patients with pre-existing liver cirrhosis. The second group of "secondary or acquired liver diseases" includes cholestatic liver diseases, as well as hypoxic liver injury and mixed forms, as well as other rarer liver diseases. Due to the diversity of liver diseases and the very different triggers, sufficient knowledge of the underlying changes (including hemodynamic changes, inflammatory states or drug-related) is essential. Early recognition, diagnosis, and treatment of the underlying disease are essential for all liver dysfunction in critically ill patients in the intensive care unit. This review article aims to take a closer look at liver diseases in the intensive care unit and provides insight into diagnostics and treatment options., (© 2024. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)
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- 2024
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16. [Cannabis use and cannabis use disorders].
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Hoch E and Preuss UW
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- Humans, Germany epidemiology, International Classification of Diseases, Adult, Dronabinol adverse effects, Cross-Sectional Studies, Intersectoral Collaboration, Substance Withdrawal Syndrome diagnosis, Substance Withdrawal Syndrome epidemiology, Mental Disorders epidemiology, Mental Disorders diagnosis, Marijuana Abuse epidemiology, Marijuana Abuse diagnosis
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Cannabis use and cannabis use disorders have taken on a new social significance as a result of partial legalization. In 2021 a total of 4.5 million adults (8.8%) in Germany used the drug. The number of users as well as problematic use have risen in the last decade. Cannabis products with a high delta-9-tetrahydrocannabinol (THC) content and their regular use lead to changes in cannabinoid receptor distribution in the brain and to modifications in the structure and functionality of relevant neuronal networks. The consequences of cannabinoid use are particularly in the psychological functioning and can include intoxication, harmful use, dependence with withdrawal symptoms and cannabis-induced mental disorders. Changes in the diagnostics between ICD-10 and ICD-11 are presented. Interdisciplinary S3 guidelines on cannabis-related disorders are currently being developed and will be finalized shortly., (© 2024. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)
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- 2024
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17. [Invasive ENT infections in immunocompetent schoolchildren in the winter half year 2022/23 : A case series].
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Frank X, Meyer S, Hufnagel-Schmude A, Dunsche A, Spetzger U, Augustin A, and Vöhringer P
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- Humans, Child, Adolescent, Female, Male, Austria, Intersectoral Collaboration, Interdisciplinary Communication, Cross-Sectional Studies, Sinusitis diagnosis, Streptococcal Infections diagnosis, Seasons, Rhinitis diagnosis, Immunocompetence
- Abstract
We report a case series of severe complications following rhinosinusitis in the winter season 2022/2023 at the Franz-Lust Hospital for children and adolescents. Due to the severity of these complications in children with suspected complicated rhinosinusitis/orbital phlegmona, an immediate interdisciplinary approach is mandatory to prevent long-term sequelae. In addition, during this time period, we observed the unusual occurrrence of a number of invasive streptococcal infections in this age cohort., (© 2024. Der/die Autor(en), exklusiv lizenziert an Springer-Verlag GmbH Austria, ein Teil von Springer Nature.)
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- 2024
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18. [Infections and liver cirrhosis].
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Dibos M, Mayr U, Triebelhorn J, Schmid RM, and Lahmer T
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- Humans, Mycoses diagnosis, Mycoses etiology, Cross-Sectional Studies, Opportunistic Infections mortality, Opportunistic Infections diagnosis, Opportunistic Infections immunology, Risk Factors, End Stage Liver Disease mortality, End Stage Liver Disease diagnosis, Virus Diseases complications, Virus Diseases diagnosis, Liver Transplantation, Immunocompromised Host, Survival Rate, Liver Cirrhosis complications, Liver Cirrhosis mortality, Liver Cirrhosis diagnosis, Bacterial Infections diagnosis
- Abstract
End-stage liver disease is a life-threatening clinical syndrome combined with a state of immune dysfunction. In this constellation patients are prone to bacterial, fungal and viral infections associated with markedly increased morbidity and mortality rates. Bacterial infections are the most prevalent kind of infection in patients with end-stage liver disease accounting for nearly 30%. The evolving rates of multidrug resistant organisms present enormous challenges in treatment strategies. Therefore, the urgent needs for prevention, early detection strategies and widespread treatment options are a necessity to handle the rising incidence of infection complications in end-stage liver disease., (© 2024. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)
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- 2024
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19. [Ten key statements of the S3 guideline "Epidemiology, diagnosis, and treatment of adult patients with nosocomial pneumonia"].
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Rademacher J and Kluge S
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- Humans, Germany, Adult, Anti-Bacterial Agents therapeutic use, Cross-Sectional Studies, Cross Infection epidemiology, Cross Infection diagnosis, Cross Infection prevention & control, Risk Factors, Pneumonia, Bacterial diagnosis, Pneumonia, Bacterial epidemiology, Intensive Care Units, Healthcare-Associated Pneumonia diagnosis, Healthcare-Associated Pneumonia epidemiology, Healthcare-Associated Pneumonia therapy
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- 2024
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20. [Pediatric emergency patients in the emergency departments of a German metropolitan region : A retrospective cross-sectional study over a one-year period].
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Althammer A, Trentzsch H, Prückner S, Gehring C, and Hoffmann F
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- Humans, Cross-Sectional Studies, Child, Retrospective Studies, Germany, Male, Child, Preschool, Female, Infant, Adolescent, Hospital Bed Capacity statistics & numerical data, Health Services Needs and Demand trends, Health Services Needs and Demand statistics & numerical data, Hospitals, Urban statistics & numerical data, Intensive Care Units, Pediatric statistics & numerical data, Emergency Service, Hospital statistics & numerical data, Emergency Service, Hospital organization & administration
- Abstract
Background: To date, no detailed analysis of pediatric emergencies treated in emergency departments (ED) exists. However, in the context of capacity planning and upcoming emergency care reform in Germany, these data are urgently needed., Methods: Retrospective, multicenter cross-sectional study for the period 01 July 2013 to 01 June 2014 of pediatric cases in emergency departments in Munich., Results: A total of 103,830 cases were analyzed (age: 6.9 ± 5.4 years, boys/girls 55%/45%). A total of 85.9% of cases were treated as outpatients, 12.4% (9.6 per 100,000 children) were admitted to normal and 1.7% (1.0 per 100,000 children) to intensive care. However, the real bed requirements exceeded these guideline numbers, with an absolute requirement of 4.9 ICU beds and 35.1 normal ward beds per day. Load peaks were seen on Wednesday and Friday afternoons and on weekends. Every 8th patient who presented to an ED as a self-referral was treated as an inpatient., Conclusion: Capacity planning for inpatient emergency care of pediatric patients requires planning for more beds than can be expected on a population basis. The availability of panel physician care influences patient volume in the EDs. Initial medical assessment tools for treatment need and urgency are needed to distribute patients. The pediatric emergency centers planned as part of the current reform of emergency care must be adequately staffed and financed in order to be able to handle-in close cooperation with statutory health insurance-accredited medical care-the expected demand for care., (© 2023. The Author(s).)
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- 2024
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21. [Epidemiological data and medical care situation of patients with chronic inflammatory diseases in Germany : Real-world evidence on prevalence, disease combinations, care].
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Riemekasten G, Schmelz R, Schäkel K, Thaci D, Schreiber S, Röcken M, Bartz H, Ploner T, Liao X, Weber V, Manz KC, Burkhardt H, and Leipe J
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- Humans, Germany epidemiology, Female, Middle Aged, Male, Adult, Aged, Prevalence, Young Adult, Adolescent, Aged, 80 and over, Chronic Disease epidemiology, Child, Age Distribution, Child, Preschool, Sex Distribution, Infant, Cross-Sectional Studies, Infant, Newborn, Retrospective Studies, Utilization Review, Rheumatic Diseases epidemiology, Rheumatic Diseases therapy, Risk Factors, Comorbidity
- Abstract
Background: Chronic inflammatory diseases (immune-mediated inflammatory diseases, IMID) can overlap or occur simultaneously due to clinical similarities. The resulting utilization of heathcare structures has not yet been investigated across disciplines but is of potential importance for optimizing the treatment of patients with IMID., Aim of the Work: Analysis of epidemiological data including utilization of care services in patients with selected IMIDs: psoriasis, psoriatic arthritis (PsA), rheumatoid arthritis (RA), ankylosing spondylitis, ulcerative colitis, Crohn's disease and connective tissue disease., Material and Methods: In a retrospective cross-sectional analysis based on health insurances accounting data with a sample of approximately 4 million insured persons, the prevalence of the abovementioned IMID and the frequency of IMID combinations were analyzed based on documented diagnoses (ICD-10 GM). The frequency of hospitalizations and utilization of outpatient physician contacts was recorded in predefined specialist disciplines (general medicine, dermatology, gastroenterology, rheumatology) and compared with an age-adjusted and gender-adjusted reference population., Results: A total of 188,440 patients had at least 1 of the IMID diagnoses analyzed (4.7%), with an age peak of 61-70 years. The highest prevalence was observed for psoriasis (1.85%), followed by rheumatoid arthritis (1.38%). Combinations with at least one other IMID were relatively common (29%), with this being most common in patients with psoriatic arthritis (82.9%, of which 68.2% had psoriasis), followed by ankylosing spondylitis (27.5%) and Crohn's disease (21.6%). Compared to the reference population, patients with IMID were hospitalized more often and more frequently utilized the outpatient disciplines., Discussion: The study results describe that IMIDs occur in combination and that the patients make comparatively more use of care structures of different disciplines. A multidisciplinary approach could increase the efficiency of care; an evaluation is still pending., (© 2023. The Author(s).)
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- 2024
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22. Stimmungsbild des ärztlichen Nachwuchses in der Frauenheilkunde und Geburtshilfe in Norddeutschland: Eine umfassende Bestandsaufnahme ausbildender Kliniken im Bereich der Norddeutschen Gesellschaft für Gynäkologie und Geburtshilfe mit Charakterisierung des ärztlichen Nachwuchses und einer praxisorientierten Herangehensweise in Vorbereitung auf die Generation Z
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Scharf, Jann Lennard, Bringewatt, Arne, Dracopoulos, Christoph, Rody, Achim, and Gembicki, Michael
- Abstract
Copyright of Der Gynäkologe is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2022
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23. [Critical care nurses' decision-making regarding verification of blindly inserted gastric tubes: A cross-sectional questionnaire study].
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Grebe M, Roos M, Höckelmann C, Sadat B, Eder C, Dichter MN, and Köpke S
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- Humans, Cross-Sectional Studies, Surveys and Questionnaires, Germany, Clinical Decision-Making, Intensive Care Units, Enteral Nutrition nursing, Critical Care Nursing standards, Intubation, Gastrointestinal nursing
- Abstract
Critical care nurses' decision-making regarding verification of blindly inserted gastric tubes: A cross-sectional questionnaire study Abstract: Background: Which methods are used by nurses in German intensive care units for verification of the correct position of blindly applied gastric tubes and how do they assess the reliability of different methods? Question: Which methods are used by nurses in German intensive care units for verification of the correct position of blindly applied gastric tubes and how do they assess the reliability of different methods? Methods: Multicenter questionnaire survey. Intensive care units in a non-probability, citeria-based sampling of hospitals in and around Cologne, Germany were included. One nurse was included per participating ward. Analyses were mostly descriptive. Results: In 22 hospitals, 38 wards agreed to participate and 32 (84%) responded to the survey. Auscultation of the upper abdomen with simultaneous air insufflation and aspiration of gastric secretions are frequently used methods for determining the position of gastric tubes. Participants consider auscultation, aspiration of gastric secretions, and radiological control as reliable methods. Conclusions: The findings are in contrast to international recommendations and support the need for evidence-based best practice recommendations and training. Likewise, there is a need for research on feasible bedside methods.
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- 2024
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24. [Benefits and harms of cannabis-based medicines from the viewpoint of patients with chronic pain and their physicians : A cohort study in three pain centers of the German federal state Saarland].
- Author
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Böttge-Wolpers C, Bialas P, Gottschling S, Juckenhöfel S, Konietzke D, Madlinger A, Welsch P, and Häuser W
- Subjects
- Humans, Male, Female, Germany, Middle Aged, Cross-Sectional Studies, Adult, Aged, Cohort Studies, Surveys and Questionnaires, Attitude of Health Personnel, Chronic Pain drug therapy, Medical Marijuana therapeutic use, Medical Marijuana adverse effects, Pain Clinics
- Abstract
Background: There are no studies available that have simultaneously assessed the benefits and harms of cannabis-based medicines from the viewpoint of patients and their physicians., Methods: All chronic pain patients at three pain centres in the German federal state of Saarland who had received at least one prescription of cannabis-based medicines (CbMs) in the past from the study centre were included in a cross-sectional study from January 1 to December 31, 2021. Patients and their physicians completed a self-developed questionnaire separately., Results: All 187 contacted patients participated in the study. Since the start of CbM therapy, 44.9% of patients reported to be much or very much, 43.3% to be moderately and 8.0% to be slightly improved overall. A total of 2.7% reported no change and 1.1% a moderate deterioration of overall wellbeing. From the patients' point of view, the symptoms most frequently reported to have substantially improved were sleep problems (36.4%), muscle tension (25.1%) and appetite problems (22.1%). The most frequent bothersome side effects were sweating (6.4%), concentration problems (4.2%) and nausea (4.1%). Physicians noted substantial pain relief in 60.7%, improvement of sleep in 65.7% and of mental well-being in 34.3%. A complete cessation of opioids was achieved in 64.7%, of anticonvulsants in 57.9% and of antidepressants in 60% of patients that had received these medications before the start of CbM therapy., Conclusions: CbMs can contribute to a clinically relevant reduction in pain, sleep problems and muscle tension and can improve daily functioning in carefully selected and supervised patients with chronic pain. CbM can contribute to the reduction or complete cessation of other pain medications (antidepressants, anticonvulsants, opioids)., (© 2023. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)
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- 2024
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25. [Factors that influence the use of sepsis-related competencies in health professionals and how they promote their patients' sepsis knowledge: Results of a mixed methods study with health professionals].
- Author
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Piedmont S, Baier L, Ullrich N, Fitz I, Sprünken E, Toubekis E, Albrecht V, and Neugebauer E
- Subjects
- Humans, Cross-Sectional Studies, Germany, Female, Male, Adult, Health Knowledge, Attitudes, Practice, Early Diagnosis, Middle Aged, Health Personnel education, Attitude of Health Personnel, Sepsis prevention & control, Clinical Competence
- Abstract
Background: Sepsis is a life-threatening and relatively common emergency which is often recognized too late or not at all. Therefore, the "SepsisWissen" (SepsisKnowledge) project aimed to bring about changes in health care professionals' behavior in the area of sepsis prevention and early detection. It addressed the health care professionals themselves (e. g., their own vaccination, hygiene and early detection behavior) and their patient counseling behavior. To promote this behavior, the SepsisWissen campaign included offers such as trainings or print products. The subsequent core question is: From the health professionals' perspective, which barriers and facilitators affect their own application of sepsis competence and their promotion of their patients' sepsis competence?, Methods: This paper was based on a cross-sectional mixed-methods study part of "SepsisWissen" withPart a) was analyzed using qualitative oriented content analysis based on Mayring, part b) was analyzed descriptively. The interviewees included physicians, nurses, pharmacists, assistants to physicians and pharmacists and, additionally, one paramedic in the quantitative sample. Some of them had attended "SepsisWissen" trainings., Results: The qualitative data analysis identified 41 conducive and hindering factors, which can be assigned to the following eight major topics: 1) syndrome sepsis; 2) predisposing factors for health professionals' own acquisition and application of sepsis competence; 3) enabling factors for health professionals themselves; 4) behavior and lifestyle of patients; 5) reinforcing factors for patients; 6) public health education; 7) political, administrative, and organizational context; 8) environmental factors. In the qualitative and quantitative surveys, the suggestion to improve the sepsis competence of the population and to reduce misinformation, respectively, through public education (e.g., via schools or the media)., Discussion: Sepsis training for health professionals was considered as a facilitating factor for taking potential sepsis symptoms and patients' respective statements more seriously. Future training formats should convey more explicitly how health professionals can better communicate their own sepsis knowledge to their patients. They request instruments to support their communication, such as checklists for lay persons. According to the interviews, health workers themselves need recurring external reminders for the topic of sepsis. Organizational and political conditions should be improved. From the health professionals' point of view, it is essential to offer better reimbursement for prevention and counseling services and to allocate adequate time resources for both., Conclusion: Health professionals could increase their potential to apply and promote sepsis competence if general conditions were optimized. From their perspective, it is most important to relieve them of some of their patient counselling burden by initiating more public education., (Copyright © 2024. Published by Elsevier GmbH.)
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- 2024
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26. [Promoting active mobility in old age through urban design].
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Baumgart S and Bolte G
- Subjects
- Humans, Germany, Aged, Health Promotion, Environment Design, Cross-Sectional Studies, Female, Male, Walking statistics & numerical data, Aged, 80 and over, Bicycling statistics & numerical data, Independent Living, Mobility Limitation, Urban Population statistics & numerical data, City Planning
- Abstract
In an ageing society, maintaining independent mobility into old age is an important objective. Mental and physical wellbeing depends not only on individual health status, but also to a large extent on the spatial conditions. Local politics and municipal administrations can influence this, especially in urban planning. This discussion article brings together perspectives from public health and urban planning on urban development and mobility against the background of health equity.The results of the AFOOT (Securing urban mobility of an ageing population) cross-sectional study on socio-spatial conditions in small- and medium-sized towns in northwestern Germany and walking and cycling by older people show the importance of residential environmental factors such as proximity to everyday destinations, walking and cycling infrastructure, and street connectivity. Preferences for the design of an age-friendly living environment and the quality of public spaces exist in terms of urban design quality, quality of stay, and safety in public spaces.In order to improve spatial conditions, the situation needs to be recorded using defined indicators and monitoring, and the perspectives of older people need to be integrated. Strategies and measures to promote active mobility in old age are aimed at the multifunctional design of public spaces, the prioritization of active mobility on everyday trips, and ensuring the accessibility of everyday destinations through urban development. Cross-sectoral cooperation between urban planning, transport planning, and public health is essential to promote the active mobility and health of older people., (© 2024. The Author(s).)
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- 2024
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27. „Die Arthroseprävalenz wird sich bis 2050 verdoppeln!“.
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Kraus D
- Subjects
- Humans, Cross-Sectional Studies, Germany epidemiology, Forecasting, Aged, Osteoarthritis epidemiology
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- 2024
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28. [Midwives as influencers in skin care for newborns at risk of atopic diseases : Survey of midwives' current recommendations].
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Staubach-Renz P, Schulz S, Weyer-Elberich V, Peveling-Oberhag A, Zimmer S, Wegner J, Sohn A, Mann C, and Lang BM
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- Humans, Infant, Newborn, Female, Adult, Germany epidemiology, Male, Surveys and Questionnaires, Cross-Sectional Studies, Practice Guidelines as Topic, Middle Aged, Midwifery, Skin Care, Dermatitis, Atopic epidemiology
- Abstract
Introduction: The prevalence of atopic diseases remains high. Initial studies suggest that primary prevention with regular basic care may influence the incidence of atopic dermatitis in infants; however, data are unclear. Midwives play an important role in the care of women in the peripartum period and therefore also in providing advice on topics such as skin care, breastfeeding and nutrition of the newborn and young infant. The aim of this study was to determine the care recommendations for newborns by midwives., Methods: We conducted a cross-sectional survey among German midwives using questionnaires on the topic of newborn skin care., Results: A total of 128 questionnaires were analyzed. The most common recommendations were oil-based herbal topicals (34.9%) and plain water (34.0%). Approximately 70% of midwives reported recommending various options when there was a known family history of atopic diathesis. It was remarkable that most of the midwives' recommendations were identical regardless of the presence of an atopic diathesis. Essential care products are only used "when necessary"., Conclusion: Training programs for midwives on the topic of "care and strengthening of the skin barrier", taking into account the current guidelines for allergy prevention, should be implemented., (© 2024. The Author(s).)
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- 2024
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29. [Acquisition, status and transfer of knowledge in compression therapy : Cross-sectional study in healthcare professions using phlebological compression therapy].
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Protz K, Dissemond J, Augustin M, and Janke TM
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- Humans, Cross-Sectional Studies, Germany, Female, Male, Adult, Surveys and Questionnaires, Middle Aged, Clinical Competence, Health Knowledge, Attitudes, Practice, Health Personnel education
- Abstract
Background: Due to scientific progress, healthcare professionals should regularly undergo appropriate continuing education. For this, knowledge transfer is essential. Therefore, the aim of this cross-sectional study was to investigate the acquisition, status and transfer of knowledge of professional groups applying phlebological compression therapy in Germany., Materials and Methods: Healthcare professionals (physicians, nurses and medical assistants) received a questionnaire developed for this study, which queried different aspects of acquisition, status and transfer of knowledge., Results: Responses from 522 participants were analysed. The topic of compression therapy was not taught in the nursing or medical education of 43.3%. Specialist journals that address compression therapy were read regularly (at least 6 times/year) by 16.1% of the participants; 63.0% had no specialist books on this subject. Only 6.7% were aware of AWMF ("Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften") guidelines on the topic and 16.3% of the corresponding DNQP ("Deutsches Netzwerk für Qualitätsentwicklung in der Pflege") expert standard. In all, 41.2% participated in at least one internal training on compression therapy per year, 72.0% in external training and 19.2% in online training. A total of 30.7% stated that they did not use any information sources to acquire knowledge., Conclusions: Possible sources of knowledge about compression therapy in Germany are insufficiently known within the investigated healthcare professional groups studied or are not regularly used. The result is a considerable knowledge deficit with a discrepancy between the current state of science and practice., (© 2024. The Author(s).)
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- 2024
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30. [Kinesiophobia in shoulder disorders : Validation of the German version of the Tampa scale for kinesiophobia (TSK-GV)].
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Pagels L, Lüdtke K, and Schäfer A
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- Humans, Male, Female, Adult, Middle Aged, Cross-Sectional Studies, Reproducibility of Results, Surveys and Questionnaires, Pain Measurement, Germany, Translating, Cross-Cultural Comparison, Disability Evaluation, Kinesiophobia, Phobic Disorders psychology, Phobic Disorders diagnosis, Shoulder Pain psychology, Shoulder Pain diagnosis, Psychometrics, Fear psychology
- Abstract
Background: With a prevalence of 7-30%, shoulder disorders form the third largest group of musculoskeletal complaints. Their formation and development is influenced by, e.g. psychological factors. The Tampa scale for kinesiophobia (TSK) is the most common measure for quantifying fear of movement., Objectives: To investigate the reliability and validity of the German version of the TSK (TSK-GV) in a shoulder pain population., Materials and Methods: Subjects with shoulder pain were included in a multicenter cross-sectional study. In addition to kinesiophobia, pain intensity, subjective impairment in daily life and fear-avoidance beliefs were recorded., Results: A total of 49 subjects (24 women and 25 men) with a mean age of 41.8 (SD = 12.8) were included. The descriptive evaluation at item level showed good internal consistency (Cronbach's α = 0.81). The homogeneity of the scale is poor (Loevinger's H = 0.35). The correlations did not show any clear convergence of the TSK-GV with the fear-avoidance beliefs questionnaire (FABQ) (r = 0.3501; p = 0.0137). The divergent validity was confirmed for both the numerical rating scale (NRS) (r = 0.1216; p = 0.4052) and the shoulder pain and disability index (SPADI) (r = 0.2571; p = 0.0745). The hypothesis testing resulted in 28.57% accepted hypotheses. There was a significant influence of the TSK-GV and the FABQ on the duration of complaints (R
2 = 0.3652; p ≤ 0.0001), as well as an explained variance of the duration of complaints on the TSK-GV of R2 = 0.1834 (p = 0.0021). The subgroup analysis showed a significantly higher degree of kinesiophobia in male subjects (t = 3.8084/df = 47; p = 0.0002)., Conclusion: The TSK-GV is a reliable measurement tool. The construct validity should be further investigated in future studies. This study shows comparable values to previous studies in other populations. The TSK-GV is to date the only validated German language measure for recording fear of movement in shoulder disorders and shows an acceptable fit for this population., (© 2022. The Author(s).)- Published
- 2024
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31. [The population perspective in assessing the performance of Germany's health care system: Results of a cross-sectional survey among members of a statutory health insurance].
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Hengel P, Köppen J, Achstetter K, Blümel M, Haltaufderheide M, and Busse R
- Subjects
- Humans, Germany, Cross-Sectional Studies, Middle Aged, Female, Male, Adult, Aged, Health Services Accessibility economics, Socioeconomic Factors, Young Adult, Adolescent, Delivery of Health Care economics, Surveys and Questionnaires, Health Literacy statistics & numerical data, National Health Programs
- Abstract
Introduction: Since the World Health Report in 2000, Health System Performance Assessment (HSPA) has been established as a tool for the evaluation and evidence-informed governance of health systems. So far, the population perspective has not been integrated into HSPA in a systematic manner, although people's experiences and expectations are of great importance to improve health systems and especially to strengthen patient-centered care. Therefore, this study aims to conduct an HSPA of Germany's health system from the population's perspective covering all eight goals of WHO's Health Systems Framework, and to identify strengths and needs for improvement., Methods: In 2018, 32,000 people insured with the German sickness fund 'AOK Nordost' were invited by mail to participate in the survey. The questionnaire contained a total of 43 items covering the eight goals of WHO's Health Systems Framework (e.g., access, quality, safety) plus socioeconomics and other characteristics of the insured persons. The data on the health system goals were analyzed descriptively and by subgroups (age, sex, income, chronic conditions, health literacy)., Results: The sample (n=1,481; response rate 4.6%) was 54.8% female and had a mean age of 59.1 years (±18.5). Altogether, the participants saw several needs for improvement within the German health system. For instance, 60.0% found quality differences between hospitals to be big, and between 3.9% and 8.5% reported mistakes related to their treatment or prescription medication in the previous two years. A big need for reform was especially seen regarding out-of-pocket payments (51.5%) and the coordination of ambulatory care physicians among each other (44.2%) and with hospitals (41.9%). In addition, big subgroup differences were seen, especially for income and health literacy. Of the participants in the lower income group, 37.2% reported a (very) strong financial burden due to out-of-pocket payments (vs. 20.7%). People with limited health literacy (52.1%) assessed the access to care generally as not being good, and they perceived greater quality differences and needs for reform, compared to their counterparts. For instance, 36.6% had experienced discrimination in the previous year (vs. 19.9%)., Discussion: The survey results provide a comprehensive picture of Germany's health system from the population perspective. In some areas, previous findings were confirmed (e.g., a lack of coordination between providers). Other results expand existing knowledge (e.g., the role of health literacy in health care provision) or raise new questions (e.g., the difference between the subjectively assessed burden from out-of-pocket payments and the objective measures currently used). The great differences between subgroups are a call to action on the level of both politics and practice to better consider the individual's needs in order to make health better for everyone. Further research could provide deeper insights in this regard., Conclusion: Strengthening the population perspective in HSPA allows for a better understanding and evaluation of health systems and, in particular, helps to identify areas for improvement in patient-centered care., (Copyright © 2023. Published by Elsevier GmbH.)
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- 2024
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32. [Sleep behavior after reverse shoulder replacement in comparison to a healthy control group : An exploratory cross-sectional study].
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Manser M, Zdravkovic V, Traber E, Erlacher D, and Jost B
- Subjects
- Humans, Cross-Sectional Studies, Male, Female, Middle Aged, Aged, Actigraphy, Sleep physiology, Sleep Wake Disorders etiology, Sleep Quality, Arthroplasty, Replacement, Shoulder adverse effects, Arthroplasty, Replacement, Shoulder methods
- Abstract
Background: Individuals with shoulder pathologies frequently report sleep problems. Improving sleep quality is a treatment focus of shoulder arthroplasty. So far, it is unclear whether altered anatomy and biomechanics in reversed total shoulder arthroplasty affect sleep quality in the long term. In addition to a subjective evaluation, a reliable assessment can be obtained by recording objective sleep parameters. With the help of actigraphy, body movements are registered and divided into active and inactive phases by means of threshold values. Thanks to the valid correspondence with waking and sleeping phases, the calculation of objective sleep parameters is successful., Objectives: The aims of the study were to investigate whether objective sleep parameters differ in persons with reversed total shoulder arthroplasty (RTSA) 1 year postoperatively compared to a healthy control group and to explore what the reasons are., Material and Methods: The present work is an exploratory cross-sectional study with one measurement time point. 29 study participants (15 in the RTSA-group, 14 in the control group) collected objective sleep parameters and body position data during seven nights using actigraphy. The Mann-Whitney-U test was used for the mean comparison of sleep parameters. In addition, reasons for wakefulness were explored., Results and Conclusions: The groups showed no significant differences in all objective sleep parameters with nearly identical sleep efficiency (p = 0.978). In the RTSA-group, 11% lay on the operated side and 65% on the back. This is just above the significance level compared to the control group with 45% in the supine position (p = 0.056). The increased use of the supine position could promote sleep-related medical conditions such as sleep apnoea and requires further research., (© 2024. The Author(s).)
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- 2024
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33. [Obesity and kidney disease].
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Oesch-Régeni B and Schultes B
- Subjects
- Humans, Risk Factors, Kidney Diseases physiopathology, Kidney Diseases etiology, Kidney Diseases therapy, Comorbidity, Cross-Sectional Studies, Obesity complications, Obesity physiopathology
- Abstract
Introduction: The obesity epidemic has led to an increased prevalence of obesity-related glomerulopathy (ORG). This disease is characte-rized by proteinuria, glomerulomegaly, progressive glomerulosclerosis and a decline in renal function. Individuals with obesity frequently display arterial hypertension and diabetes mellitus, exacerbating renal damage. The pathogenesis involves overactivation of the RAAS (Renin-Angiotensin-Aldosterone System), glomerular hyperfiltration, an inflammatory state with oxidative stress, hyperinsulinemia-induced hemodynamic alterations and lipotoxicity. Additionally, obesity represents a significant risk factor for kidney stone formation, further contributing to renal damage. The management of obesity-induced nephropathy primarily involves weight reduction strategies and optimized control of blood pressure and metabolic factors. Early detection is crucial to counteract the progression of kidney disease. Noteworthy, obesity significantly complicates the implementation of renal replacement procedures, including kidney transplantation, and increases the rate of complications. In summary, there are many reasons why obesity should gain attention in the field of nephrology., Competing Interests: Die Autoren haben keine Interessenkonflikte im Zusammenhang mit diesem Artikel deklariert., (© 2024 Aerzteverlag medinfo AG.)
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- 2024
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34. [Insured Persons with High and Moderate Risk of Reduced Earning Capacity - Identification, Analysis of the Use of a Counselling Service and Illustration of their Health and Occupational Situation].
- Author
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Passier I, Kröger C, and Kobelt-Pönicke A
- Subjects
- Humans, Germany, Male, Female, Middle Aged, Adult, Disabled Persons rehabilitation, Disabled Persons statistics & numerical data, Young Adult, National Health Programs statistics & numerical data, Work Capacity Evaluation, Cross-Sectional Studies, Counseling
- Abstract
Purpose: The aim of this study was to investigate the life situation, and analyse the need for rehabilitative interventions as well as the use of counselling service offered to persons insured by the German Pension Insurance Braunschweig - Hannover (DRV BS-H), using the moderate and high risk index for temporary disability penson (RI-EMR)., Method: This is a cross-sectional study. The participants were generated from a random sample of the total insured persons of the DRV BS-H. 1778 persons were contacted offering telephone consultation and a request for participation in a questionnaire survey that recorded, among others, symptoms, burdens and impairments. Employed persons were asked about their stress at work, non-employed persons about their motivation to return to work. 391 (24.5%) participated in the questionnaire survey and 157 (9.8%) of those contacted responded to the offer of counselling service. The contents of the counselling sessions were evaluated descriptively. The questionnaire data were analysed comparatively (ANOVA, χ2-test)., Results: The offer of the telephone counselling was not used as expected in advance. Insured persons with a high RI-EMR showed more clearly complaints as well as burdens and impairments due to contextual factors than persons with a moderate RI-EMR. The majority of non-employed persons in both groups showed up in the motivational stage of forming intentions with regard to a possible return to employment., Conclusion: The question arises as to how insured persons with prognostically limited participation can be better reached with offers of assistance. The goal of early offer of support services is confronted with the problem that delays occur in the application of the routine data of the DRV and thus of the RI-EMR. Future studies should investigate how to improve insured persons' participation in counselling services and also their motivation to return to work., Competing Interests: Die Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)
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- 2024
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35. [Nutrition counseling in medical practices-a cross-sectional study].
- Author
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Mertens HL and Kaifie A
- Subjects
- Germany, Cross-Sectional Studies, Humans, Female, Male, Adult, Counseling, Surveys and Questionnaires, Middle Aged, Attitude of Health Personnel, Nutrition Therapy methods, Practice Patterns, Physicians' statistics & numerical data
- Abstract
Introduction: The purpose of this study was to assess the status of nutrition care and counseling in German medical practices, including physicians' nutrition interest and knowledge, existing obstacles, and possible ways of improving nutrition care., Methods: After development and a two-stage pretest, questionnaires with 32 items were distributed to all resident doctors of general medicine, internal medicine, gynecology and obstetrics, orthopedics, and occupational medicine in Aachen (n = 360) in early spring 2022., Results: The response rate was 29.2% and n = 105 participants were included in the analysis. During their consultation hours, 85.7% of the doctors conducted nutrition counseling (NC). While doctors estimated that 39.5% of their patients need NC, they counseled only 28.1%. General practitioners spent an average of 13 min on NC; all other specialties spent 9.5 min. Most participants felt well informed about healthy nutrition (95.2%). Nutrition was of high personal interest to 57.7% of the participants, and 47.6% considered it important for their work as a doctor. Barriers preventing better NC included the lack of nutrition education during medical studies (89.5%) and specialist training (79.6%), and the lack of time (75.2%). Most participants were willing to conduct more NC if they were paid better and had more time for NC during their working hours., Discussion: Doctors consider NC a relevant part of their work, despite many barriers. To make better use of NC as a measure for treating and preventing common diseases, improvements like better nutrition education for doctors, better funding, and more time for NC are required., (© 2024. The Author(s).)
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- 2024
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36. [Prevalence of neuropsychiatric symptoms of people with dementia in long-term care units: A secondary analysis].
- Author
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Hüsken JM, Halek M, Holle D, and Dichter MN
- Subjects
- Humans, Aged, Female, Male, Cross-Sectional Studies, Germany, Aged, 80 and over, Neuropsychological Tests statistics & numerical data, Alzheimer Disease nursing, Alzheimer Disease epidemiology, Alzheimer Disease psychology, Dementia epidemiology, Dementia nursing, Dementia psychology, Psychomotor Agitation nursing, Psychomotor Agitation epidemiology, Psychomotor Agitation psychology, Aggression psychology, Mental Disorders epidemiology, Mental Disorders nursing, Nursing Homes statistics & numerical data, Homes for the Aged statistics & numerical data, Long-Term Care
- Abstract
Prevalence of neuropsychiatric symptoms of people with dementia in long-term care units: A secondary analysis Abstract: Background: In a progress of dementia, most people develop neuropsychiatric symptoms. However, there is little knowledge about the prevalence of these symptoms and their specific characteristics in long-term care. Aims: A differentiated investigation of the prevalence and characteristics of neuropsychiatric symptoms in people with dementia in a long-term care setting. Methods: The prevalence of neuropsychiatric symptoms of people with dementia in a long-term care setting was examined using a secondary analysis of cross-sectional data from the research projects LebenQD I and II and FallDem. The data were collected using the neuropsychiatric inventory - nursing home version. The analysis included data from 699 people with dementia from a total of 21 long-term care facilities in North Rhine-Westphalia. Results: The symptoms agitation/aggression (36%), depression/dysphoria (33%), apathy/indifference (33%), irritability/lability (30%) and aberrant motor behaviour show the highest prevalence. The symptoms hallucinations (9%) and euphoria/elation (6%) have the lowest prevalence. Conclusions: The high prevalence of specific neuropsychiatric symptoms and their characteristics in people with dementia illustrates the need for care-related or psychosocial interventions to counteract the reasons for the occurrence of the symptoms.
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- 2024
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37. [Insomniac symptoms and suicidality-link and management].
- Author
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Schwerthöffer D and Förstl H
- Subjects
- Humans, Risk Factors, Combined Modality Therapy, Antidepressive Agents therapeutic use, Antidepressive Agents adverse effects, Suicide psychology, Cross-Sectional Studies, Female, Adult, Male, Suicide Prevention, Sleep Initiation and Maintenance Disorders psychology, Sleep Initiation and Maintenance Disorders epidemiology, Sleep Initiation and Maintenance Disorders therapy, Comorbidity, Suicidal Ideation
- Abstract
Background: A link between insomniac symptoms and suicidality has long been suspected and deserves specific attention., Objective: We examine the current evidence for this relationship from epidemiology and neurobiology in order to propose a targeted management., Material and Method: Clinical example and selective Medline-literature research for insomnia symptoms and suicidality., Results: Epidemiological data and statistical analysis show that symptoms of insomnia are independent risk factors for suicidality. Neurobiological factors associated with combined insomnia symptoms and suicidality are: serotonergic dysfunction and circadian rhythm disorder leading to hypofrontality with reduced problem solving capacity and impaired emotional and impulse-control. Social isolation, recurrent rumination, comorbid psychiatric disorders, access to potentially lethal drugs or weapons need urgent evaluation in patients with a combination of suicidality and symptoms of insomnia., Conclusion: patients with insomnia and further risk factors for suicide need to be treated resolutely and at an early stage. Modern sleep-promoting antidepressants with low toxicity and antipsychotics must be preferred in the treatment of patients with insomniac sleep disorders and suicidality. Multimodal anti-insomnia and anti-depressive therapy adapted to the circadian rhythm can exert a favorable influence both on depressive-suicidal and insomnia symptoms and their inherent risks., (© 2023. The Author(s).)
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- 2024
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38. [Benign prostatic syndrome - epidemiology, aetiology, diagnostic evaluation].
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Kidess M, Keller P, Tamalunas A, Askari-Motlagh D, Atzler M, Karatas D, Stadelmeier L, Stief CG, and Weinhold P
- Subjects
- Aged, Humans, Male, Cross-Sectional Studies, Diagnosis, Differential, Risk Factors, Prostatic Hyperplasia diagnosis, Prostatic Hyperplasia epidemiology, Prostatic Hyperplasia etiology, Prostatic Hyperplasia therapy
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- 2024
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39. [Depressive symptoms in older prisoners : Results of two studies].
- Author
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Meyer L, Marschall T, and Verhülsdonk S
- Subjects
- Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Age Distribution, Antidepressive Agents therapeutic use, Comorbidity, Cross-Sectional Studies, Germany epidemiology, Prevalence, Risk Factors, Depression epidemiology, Depression diagnosis, Prisoners statistics & numerical data, Prisoners psychology
- Abstract
Background: The proportion of prisoners aged 60 years and above is steadily rising both nationally and internationally. With advancing age the risk of developing physical and mental illnesses also increases. International studies have demonstrated a higher prevalence of mental disorders among older prisoners compared to the general population; however, there are few data on this, at least for Germany., Objective: Collation of empirical data on the presence of depressive symptoms among older prisoners., Material and Methods: There were two independent cross-sectional studies conducted in North Rhine-Westphalia (NRW) and Rhineland-Palatinate (RLP), which included prisoners aged 50 years and above. In NRW a purely quantitative survey of depressive symptoms was carried out using the German version of the patient health questionnaire (PHQ-D) and in RLP the quantitative measurements using the general depression scale short form (ADS-K) were supplemented by qualitative interviews., Results: In total, data from 315 inmates were available for a joint analysis (222 from RLP, 93 from NRW). Among the prisoners in RLP 63.4% exhibited mild to clinically significant depressive symptoms, while in NRW this was the case for 46.2%. The treatment with antidepressants was carried out only in a small proportion in both federal states., Discussion: Both surveys showed a clearly elevated prevalence of depressive symptoms compared to the non-prison population. The results also suggest a need for optimization in terms of treatment. Particularly concerning potential interactions with somatic illnesses, efforts should be made to improve the diagnostics and treatment of depressive symptoms., (© 2024. The Author(s), under exclusive licence to Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)
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- 2024
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40. [Evidence-based practice in Bachelor of Nursing programmes in Austria, Germany, and Switzerland: A survey of general conditions, teaching content and methods].
- Author
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Jäger P, Hirt J, Nordhausen T, Vetsch J, Balzer K, Dichter MN, Müller G, Schley A, and Neyer S
- Subjects
- Austria, Humans, Germany, Switzerland, Cross-Sectional Studies, Surveys and Questionnaires, Cross-Cultural Comparison, Curriculum, Evidence-Based Nursing education, Education, Nursing, Baccalaureate
- Abstract
Background/aim: Evidence-based practice (EBP) provides an important basis for improving both the quality of care and patient safety. Formulating a research question, searching the literature, and critical appraisal are crucial to developing evidence-based practice. The aim of this survey was to provide an overview of how these topics are integrated into bachelor's degree programs in nursing in Austria, Germany, and the German-speaking part of Switzerland. We also aimed to show how teachers implement these subjects and how they experience and assess the implementation., Method: We conducted an exploratory cross-sectional study using an online survey sent out to program directors and teaching staff of all 58 bachelor's degree programs in nursing in Austria, Germany and the German-speaking part of Switzerland. For data collection, a questionnaire was developed containing items on general teaching conditions, contents, and methods of evidence-based nursing practice, as well as on the estimated thematic interest of students. The data were analysed descriptively., Results: The program directors returned 24 questionnaires (41%). Of 75 questionnaires forwarded to the faculty, 17 (23%) were received from nine programs. On average, 5.6 teaching units (SD 2.6) are used for formulating a research question, 10 teaching units (SD 4.1) for literature review, and 11.3 teaching units (SD 6.9) for critical appraisal. Half of the teaching staff indicated that linkages between education and nursing care practice have been established. The traditional teaching method of frontal teaching is used predominantly. Student interest in topics was rated as moderate by most teachers., Conclusions: Topics on evidence-based practice are an integral part of bachelor's degree programs in nursing in German-speaking countries. An increase in teaching units, active learning methods and the growing interconnection between education and practice could improve the acquisition of competencies and attitudes of students regarding EBP and further advance its implementation in practice., (Copyright © 2024. Published by Elsevier GmbH.)
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- 2024
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41. [Comprehensive nutrition therapy in hospitals - Wishful thinking or reality? A survey-based cross-sectional study of the nutritional therapy in hospitals of Baden-Württemberg].
- Author
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Adolph M, Schweikert D, Wehner A, Fritsche A, Bamberg M, Tischler K, and Wessels B
- Subjects
- Humans, Cross-Sectional Studies, Germany, Nutritional Support, Hospitals, Parenteral Nutrition, Surveys and Questionnaires, Quality of Life, Malnutrition diagnosis, Malnutrition prevention & control
- Abstract
Introduction: Malnutrition is widespread in German hospitals, has a negative impact on therapeutic success and quality of life, and it leads to increasing costs. An individualized nutritional support by nutritional professionals in accordance with current guidelines was shown to reduce mortality of malnourished inpatients. Ideally, nutritional support is conducted by an interdisciplinary nutrition support team. Current data on the nutritional therapy in German hospitals is missing., Methods: In order to ascertain the current status of nutritional support in hospitals in the federal state of Baden-Württemberg, clinic managements of all hospitals in Baden-Württemberg received an online questionnaire. Affiliated hospitals, specialist hospitals, as well as hospitals with less than 50 beds were excluded from the analysis., Results: The response rate was 84% (n = 94). The presence of a nutrition support team was reported by 34% of the hospitals. Twelve percent of the hospitals meet the structural characteristic of the OPS Code 8-98j Ernährungsmedizinische Komplexbehandlung, which means that their nutrition support team includes a physician. A validated nutritional risk screening is performed in 72% of the hospitals. Only 40% of the hospitals report that this is performed throughout every department. Nutrition support teams are more often concerned with malnutrition, enteral and parenteral nutrition as compared to nutritionists who are not organized in a team. Moreover, nutrition support teams have a wider range of tasks and more often a physician as a team member. Also, nutritional risk screenings are more often applied in hospitals with nutrition support teams., Discussion: Compared with a nationwide survey from 2004, there are markedly more nutrition support teams available in hospitals in Baden-Württemberg. When compared internationally, however, the rate of nutrition support teams is still low. In addition, there is no comprehensive nutritional care available. High-quality nutritional support is more often found in hospitals with nutrition support teams., Conclusion: There is still a great potential of improving clinical nutritional care in hospitals in Baden-Württemberg. Moreover, an increase in nutrition support teams, also comprising medical members, should be achieved. Therefore, legal regulations and a sufficient refinancing are indispensable., (Copyright © 2024. Published by Elsevier GmbH.)
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- 2024
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42. [SARS-CoV-2 Exposure and Seroprevalence of SARS-CoV-2 Antibodies among Medical Students in the First Phase of the Pandemic 2020-2021].
- Author
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Landmesser P, Weissbrich B, Peter-Kern M, Krone M, Liese JG, and Streng A
- Subjects
- Humans, Female, Young Adult, Adult, Male, SARS-CoV-2, Cross-Sectional Studies, Pandemics, Seroepidemiologic Studies, Germany epidemiology, Hospitals, University, Students, Medical, COVID-19 epidemiology
- Abstract
Background: Due to their clinical training and secondary activities in the hospital, medical students are exposed to contact with SARS-CoV-2 infected people more often than the general population. We determined the seroprevalence of SARS-CoV-2 antibodies in medical students in clinical training at different times during the pandemic and asked participants about possible SARS-CoV-2 exposures in both medical and private settings., Methods: From May 2020 to June 2021, medical students each in their 3rd year of training at the University Hospital Würzburg participated in the cross-sectional survey. All SARS-CoV-2 unvaccinated students were offered a determination of their SARS-CoV-2 serostatus. The blood samples were tested by an immunoassay (Elecsys, Roche) for IgG/IgM/IgA antibodies against the SARS-CoV-2 N antigen. Demographic data, SARS-CoV-2 disease and vaccination status, as well as possible SARS-CoV-2 exposures were collected using a questionnaire., Results: Overall, 383 (86.1%) of 445 students took part in the cross-sectional survey (65% female; median age 22 years; IQR 21-24). Serostatus was determined in 223 (58.2% of 383) SARS-CoV-2 unvaccinated participants. In the period between the beginning of the pandemic in Germany (February 2020) and the time of the survey, 332 (86.7% of 383) students stated that they worked in the medical field, mainly in the context of clinical traineeships (76.8%) or secondary activities with patient contact (48.8%); 129 (33.7%) reported previous contact with a COVID-19 patient, of which 78.3% of contacts took place at a medical facility. Antibodies against SARS-CoV-2 were detected in 8 (3.6%) of the 223 unvaccinated participants tested, and in 3 infected persons an association between infection and contact in the course of medical activity seemed likely., Conclusion: Despite frequent patient contact and the associated increased risk of infection, medical students in their 3rd year of training did not show an increased seroprevalence compared to the general population and showed a lower or similar seroprevalence rate than medical students in other European countries in the first 18 months of the pandemic. This indicates sufficient protection of medical students at the beginning of clinical training through the hygiene and infection protection measures implemented at that time during medical activities., Competing Interests: MK erhält Beratungshonorare von Abbott, GSK und Pfizer ohne Verbindung zum Inhalt des Manuskripts. JL erhält Forschungsgelder von Pfizer, Janssen, GSK, Sanofi, und MSD, und Honorare für Vorträge/Advisory Boards von Astra Zeneca, Pfizer und MSD, ohne Verbindung zum Inhalt des Manuskriptes. AS erhält Forschungsgelder von Pfizer, Janssen, GSK, Sanofi, und MSD ohne Verbindung zum Inhalt des Manuskriptes. Die anderen Autoren geben an, dass kein Interessenskonflikt besteht., (Thieme. All rights reserved.)
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- 2024
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43. [Diagnosis and therapy of patients with asthma in Germany. Results of the care study RELEVANT].
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Trinkmann F
- Subjects
- Humans, Cross-Sectional Studies, Adrenal Cortex Hormones therapeutic use, Germany, Administration, Inhalation, Nitric Oxide analysis, Nitric Oxide therapeutic use, Asthma diagnosis, Asthma drug therapy
- Abstract
Background: Diagnostic and therapeutic options for asthma have improved with asthma control and remission being of central importance. The RELEVANT study aimed for a nationwide snapshot of current asthma diagnosis and treatment in general practice and specialty care for identification of further aspects for optimization., Method: RELEVANT is a nationwide cross-sectional study using a structured questionnaire. This comprised 14 questions on asthma-related topics covering diagnostics and therapy. Participants were general practitioners/internal medicine specialists and pulmonologists., Results: A total of 1,558 persons took part in the survey. Regarding relevant specific diagnostic procedures for asthma, GPs/internists almost exclusively mentioned pulse oximetry. Among the pulmonologists, fractional exhaled nitric oxide (FeNO) measurement was mentioned, among others. FeNO and blood eosinophils were only mentioned by the pulmonologists as diagnostic and treatment-relevant markers. A total of more than 60% of the GPs/internists surveyed stated that only around 25% or fewer of their patients would voluntarily report restrictions in their everyday lives. Regarding drug treatment, the majority stated that they recognized differences between various ICS/LABA combination therapies., Conclusions: The results indicate a need for optimization, particularly regarding asthma control. This involves both a better assessment by patients' everyday life restrictions and modern ways of assessing asthma control in cooperation between GPs/internal medicine specialists and pulmonologists. One fifth of respondents do not see any differences between various ICS/LABA combinations in daily practice, although there are pharmacodynamic and pharmacokinetic differences., (© 2024. Springer Medizin Verlag GmbH, ein Teil von Springer Nature.)
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- 2024
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44. [Nursing skill levels and implementation of Advanced Nursing Practice in Austria: A cross-sectional study].
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Herzog M, Schönfelder B, Barton M, Gugler P, Aghaizu C, Nagl-Cupal M, and Mayer H
- Subjects
- Humans, Austria, Cross-Sectional Studies, Clinical Competence, Surveys and Questionnaires, Education, Nursing, Graduate
- Abstract
Nursing skill levels and implementation of Advanced Nursing Practice in Austria: A cross-sectional study Abstract: Background: New fields of practice are emerging under the concept of "Advanced Nursing Practice" (ANP) that offer specialised care provided by nurses who hold master's degrees. In Austria, nurses are currently being trained as Advanced Practice Nurses (APN). Aim: The project aimed to investigate which advanced nursing practice tasks according to the Hamric model are undertaken by nurses at different levels of qualification in Austria. Methods: Certified nurses did participate in a cross-sectional survey through an online questionnaire based on the Role Delineation Model and tailored to the Austrian context. The tasks were assigned based on the Hamric model and were tested and evaluated descriptively according to the qualification level through factor analysis. Results: Completed data was available from 105 participants, among them 80% with undergraduate education, 20% with a master's degree. A tendency in the results showed that the level of qualification was related to the activities carried out. The higher the academic degree, the more activities were performed in the field of leadership. The central ANP-competencies, research and education, are rather weak among all respondents. Conclusion: The results show that activities corresponding to the competencies of an ANP are performed by a heterogeneous group of nurses. Conditions and a standardized understanding of ANP need to be established in order to offer a professional practice that matches the competency profile.
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- 2024
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45. [Influence of guideline recommendations, care structures and individual factors on the use of psychosocial therapies in severely mentally ill people].
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Fritz S, Kösters M, Allgöwer A, Becker T, Kilian R, Gühne U, Riedel-Heller SG, Hasan A, Falkai P, Ajayi K, Baumgärtner J, Brieger P, Frasch K, Heres S, Jäger M, Küthmann A, Putzhammer A, Schneeweiß B, Schwarz M, and Breilmann J
- Subjects
- Humans, Cross-Sectional Studies, Germany, Mentally Ill Persons, Mental Disorders therapy
- Abstract
Objective: The influence of guideline recommendations and other factors on the utilization of psychosocial interventions in people with severe mental illness was examined., Methods: Data from a cross-sectional study of 397 people with severe mental illness were analysed descriptively., Results: Patients are less likely to receive therapies with a strong recommendation compared to other levels of recommendation. Various other factors are diffusely associated with utilization rates, but no ubiquitous predictors could be identified across all therapies., Conclusion: Current practice in the use of psychosocial interventions does not follow guideline recommendation strength. Interventions with strong recommendations are probably not available across services. Consequently, routine practice is not able to follow guideline recommendations according to their strength. Other consistent predictors could not be identified., Competing Interests: Alkomiet Hasan erhielt Vortragshonorare von AbbVie, Advanz, Janssen, Otsuka, Rovi, Recordati und Lundbeck. Er war Mitglied in Advisory Boards für Boehringer-Ingelheim, Janssen, Otsuka, Rovi, Recordati und Lundbeck. Einladungen zu Kongressen oder Essen wurden nicht angenommen. Er ist Herausgeber der AWMF S3-Leitlinie Schizophrenie, Angestellter des Freistaats Bayern und der Bezirkskliniken Schwaben. Karel Frasch hat Kongressreiseunterstützungen von Janssen erhalten. Er ist stellv. Sprecher von ackpa und Mitglied im Vorstand der DGPPN. Alle anderen Autorinnen/Autoren geben an, dass kein Interessenkonflikt besteht., (Thieme. All rights reserved.)
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- 2024
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46. [Immune-mediated inflammatory diseases in Germany : A cross-sectional analysis of comorbidities and pharmacotherapy].
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Leipe J, Schmelz R, Riemekasten G, Thaçi D, Henes J, Schäkel K, Pinter A, Sticherling M, Wegner J, Fusco S, Linke M, Weber V, Manz KC, Bartz H, Roecken M, Schmidt S, and Hoyer BF
- Subjects
- Humans, Cross-Sectional Studies, Retrospective Studies, Immunomodulating Agents, Arthritis, Psoriatic, Arthritis, Rheumatoid, Psoriasis, Spondylarthritis therapy
- Abstract
Background: Immune-mediated inflammatory diseases (IMID) can lead to a substantial disease burden for those affected, in particular by the concomitant occurrence of other IMIDs or in the presence of comorbidities. The care of patients with IMIDs is complex and involves various medical disciplines., Objective: To describe the burden of disease and the current routine drug treatment of patients with IMID., Material and Methods: The retrospective cross-sectional analysis was based on statutory health insurance claims data from the InGef database. Prevalent patients with psoriasis (Pso), psoriatic arthritis (PsA), spondylarthritis (SpA), rheumatoid arthritis (RA), Crohn's disease (MC), ulcerative colitis (CU), or connective tissue disease were identified among 3,988,695 insured patients in 2018. The concomitant occurrence of different IMIDs and the extent to which patients with IMID are affected by other comorbidities compared to a reference population were investigated. The current routine drug treatment was described based on the use of predefined forms of treatment., Results: In the database 188,440 patients with IMID (4.7%) were identified. Compared to the reference population the prevalence of comorbidities, such as depressive episodes and cardiovascular risk factors was higher in patients with IMID. For MC, CU, RA, and PsA disease-modifying antirheumatic drugs (DMARD) and classical systemic forms of treatment were used most commonly. In Pso, SpA, and connective tissue disease nonsteroidal anti-inflammatory drugs (NSAID) were the most frequently used treatment often in combination with other drugs., Conclusion: A considerable number of patients with IMIDs (16.9-27.5%) suffer from different diseases of the IMID group. They are frequently affected by accompanying illnesses and require interdisciplinary medical treatment., (© 2022. The Author(s).)
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- 2024
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47. [Experience with orthopaedic insoles-a cross-sectional study].
- Author
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Stamer T, Herchenröder M, Klee MW, Götz K, and Steinhäuser J
- Subjects
- Humans, Male, Female, Cross-Sectional Studies, Regression Analysis, Surveys and Questionnaires, Shoes, Orthopedics
- Abstract
Background: Orthopaedic insoles (OI) are used to treat a variety of foot problems., Objectives: The aim of this cross-sectional study was to investigate the perceptions of the treatment with OI among the manufacturers of the OIs, the orthopaedic technicians (OT)., Methods: OT from the federal states of Schleswig-Holstein and Lower Saxony in Germany were invited to take part in a survey. The questions included, among others, the number of prescriptions for the production of an OI per month and the materials used. Descriptive statistics, subgroup analyses and a linear regression analysis were performed., Results: Of the 312 questionnaires distributed, 159 were completed (response rate 51%). Most of the respondents were male (80%). The average age of the participants was 50. On average, OT produced 290 OI per month, with plastic being the most commonly used material (73%). OT with less than 20 years of professional experience are more likely to follow the doctor's instructions when producing OI than OT with more than 20 years of professional experience. The latter are more likely to base their decisions regarding the manufacture and issuing of OI on their own experience., Conclusions: The production and issuing process of OI differs among OT. The different professional perspectives of the OT could play a role here, as does the lack of a standardized procedure. The factors listed in this study represent potential starting points for future research projects that could contribute to the development of evidence-based standards., (© 2024. The Author(s).)
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- 2024
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48. [Parental strain, inattention/hyperactivity symptoms and parent-reported ADHD in children and adolescents: results of the KiGGS study].
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Neuperdt L, Beyer AK, Junker S, Mauz E, Hölling H, and Schlack R
- Subjects
- Humans, Adolescent, Cross-Sectional Studies, Germany epidemiology, Parents psychology, Multivariate Analysis, Parenting, Attention Deficit Disorder with Hyperactivity diagnosis, Attention Deficit Disorder with Hyperactivity epidemiology
- Abstract
Background: A child's attention deficit hyperactivity disorder (ADHD) is associated with strain for the parents. In turn, psychosocial parental strain is associated with higher probabilities for the occurrence of inattention/hyperactivity symptoms (IHS) in their children. The aim of this paper is to assess the association between parental strain, IHS, and a parent-reported ADHD diagnosis of the children., Methodology: Based on data from n = 4596 participants of the KiGGS cohort (wave 2: 2014-2017), the type and extent of parental strain was set in relation to IHS and an ADHD diagnosis of the child in cross-sectional analysis. Frequencies, means, beta coefficients, and odds ratios adjusted for sex, age, socioeconomic status, and migration background are reported., Results: In individual consideration, a greater number of parental strains were associated with IHS than with an ADHD diagnosis. In a multivariate analysis, financial worries and parenting problems/conflicts with the children were significant predictors of IHS and an ADHD diagnosis, respectively. In addition, four or more types of parental strain were associated with a higher likelihood of both IHS and an ADHD diagnosis., Discussion: Financial and child-rearing strain are relevant to parents of children with IHS and an ADHD diagnosis. Interrelationships between parental stress and a child's IHS or an ADHD diagnosis can be assumed. To relieve their burden, prevention can either aim at improving the situation of ADHD-affected families or at improving the family's handling of the child's ADHD., (© 2024. The Author(s).)
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- 2024
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49. [Posttraumatic stress disorder in children and adolescents: results of a cross-sectional study on the effects of the newly formulated PTSD and CPTSD diagnoses in the ICD-11].
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Eilers R, Ertl V, Kasparik B, Kost A, and Rosner R
- Subjects
- Child, Humans, Adolescent, International Classification of Diseases, Cross-Sectional Studies, Germany epidemiology, Surveys and Questionnaires, Stress Disorders, Post-Traumatic diagnosis, Stress Disorders, Post-Traumatic epidemiology
- Abstract
Background: ICD-11 presents narrowed criteria for posttraumatic stress disorder (PTSD) and introduces complex PTSD (CPTSD) with additional difficulties in self-organization (DSO). These changes can have significant effects on the frequency of the diagnosis. The aim of this study was to investigate which ICD-11 symptom clusters cause children and adolescents to miss the diagnosis and whether caregivers are more likely to attribute changes in DSO to developmental level or to the traumatic event, and how these attributions are in turn related to symptom severity., Methods: N = 88 German-speaking children and adolescents (age: 7-17 years) after traumatic events and N = 79 caregivers participated between September 2019 and November 2020 in a survey on PTSD symptom severity (CATS-2) and attribution of DSO symptoms (caregiver questionnaire)., Results: The ICD-11 criteria (CATS‑2 and a developmentally adapted version) showed lower frequency rates for PTSD as compared to DSM‑5 and ICD-10. The ICD-11 clusters re-experiencing and hyperarousal were met the least often. Changes in DSO symptoms were predominantly rated as event-related. This attribution was associated with higher PTSD and DSO symptom severity in caregiver reports. The age-related attribution was associated with higher DSO-symptom severity, but not PTSD symptom severity in caregiver reports., Discussion: In the context of the diagnostic process and the revision of diagnostic instruments for ICD-11 (C)PTSD, development-specific symptoms should be taken into account. The trauma-related differentiation of DSO symptom changes as compared to development-related fluctuations is challenging and therefore requires several sources of information., (© 2024. The Author(s).)
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- 2024
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50. [Substance use and the usage of social media, computer games, and gambling among apprentices at vocational schools].
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Lochbühler K, Rossa M, Ebert C, Morgenstern M, Arnaud N, and Kraus L
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- Humans, Cross-Sectional Studies, Germany epidemiology, Gambling epidemiology, Social Media, Substance-Related Disorders epidemiology, Video Games
- Abstract
Background: The aim of the current study was to assess the prevalence of the (problematic) consumption of alcohol, tobacco, and cannabis as well as the (problematic) use of social media, e‑products, computer games, and gambling among apprentices., Method: Cross-sectional survey of 4591 apprentices at 17 vocational schools from Bavaria, Schleswig-Holstein, and Hamburg. Data was collected using questionnaires between March 2021 and April 2022. The primary endpoints were the 30-day prevalence and the problematic consumption and usage behavior of the mentioned substances/behaviors using screening instruments., Results: Among the assessed substances/behaviors, social media were used most frequently by the apprentices with a 30-day prevalence of 97.7%, followed by alcohol (64.3%) and computer games (55.8%). Cigarettes were consumed by 35.1%, e‑products by 17.9%, and cannabis by 15.4% of the apprentices. Of the apprentices, 12.2% reported having gambled in the past 30 days. Rates of problematic use were 47.4% for alcohol, 18.0% for tobacco, 6.2% for e‑products, and 1.6% for cannabis. Problematic use of social media was indicated by 45.0% of the apprentices, of gambling by 2.2%, and of computer games by 0.7%., Discussion: These results suggest that apprentices constitute a risk group for problematic substance use, indicating increased need for intervention. In particular, secondary prevention efforts in the areas of alcohol and social media should be taken into consideration due to their widespread prevalence in the vocational school setting., (© 2024. The Author(s).)
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- 2024
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