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The use of cotton swabs is well known as a cause of a traumatic membrane perforation. More reasons are known. A detailed description of the aetiology and therapy in Germany does not exist. The treatment consist of a readaptation of the perforation an splinting of the tympanic membrane with paper sheets or silicon foils.238 patients with an acute tympanic membrane perforation were included in this retrospective study. They were treated between 2005 and 2010.The mean causes of a traumatic tympanic membrane perforation were slaps with the open hand (37.4%), the use of a cotton swab (19.3%) and high diving (13.0%). The perforations have been splinted with paper sheets or silicon foils. The rate of complete wound closure after splinting with different materials are comparable (71.9% and 81.8%). The side effects are low.This is the first study about the aetiology of traumatic tympanic membrane perforations in Germany. There is no statistic difference between the 2 materials for tympanic membrane splinting. A traumatic tympanic membrane perforation should be treatet at least to improve the air conduction threshold.

HINTERGRUND: Der temporÄre Einsatz eines Magenballons zur Behandlung der Adipositas Grad1 und 2 nimmt weltweit zu; bei der Adipositas Grad 3 wird der Magenballon als adjuvantes Hilfsmittel zur prÄoperativen Gewichtsreduktion implantiert. Ziel dieser retrospektiven Kohorten analyse ist, die Wirksamkeit des Magenballons auf Gewichtsreduzierung und das Risikoprofil der Methode zu evaluieren. METHODEN: Retrospektive Kohortenanalysen aus 4 Adipositas-Zentren, in denen der Magenballon seit 2001 regelmÄßig implantiert wurde. ERGEBNISSE: Von Februar2001 bis April 2008 wurde bei 634 Patienten ein Magenballon implantiert (BIBTM Intragastric Balloon System; Allergan Medical, Irvine, CA, USA). Die Geschlechterverteilung war 31,5% MÄnnerzu 68,5% Frauen; das Durchschnittsalter betrug 41,5 Jahre. Das durchschnittliche Ausgangsgewicht lag bei 126 kg. Der initiale BMI bei Implantation des Magenballons war 42,5 kg/m(2). Die Implantation der Prothese war in allen FÄllen unkompliziert. Der durchschnittliche Gewichtsverlust lag bei 20,75 kg bzw. 7,05 BMI-Punkten. SUMMARY: The Gastric Balloon — a Retrospective Cohort Analysis with 634 Patients BACKGROUND: The temporary use of a gastric balloon for the treatment of obesity grade 1 and 2 is increasing worldwide, whereas in grade 3 obesity, it is implanted as a tool for preoperative adjuvant weight loss. The aim of this retrospective cohort analysis is to evaluate the effectiveness of weight reduction and to describe the risk profile of the method. METHODS: Retrospective cohort analysis of 4 obesity centers where gastric balloons had been regularly implanted since 2001. RESULTS: Between February 2001 and April 2008, the gastric balloon (BIBTM Intragastric Balloon System; Allergan Medical, Irvine, CA, USA) was implanted in 634 patients. The gender ratio was 31.5% males to 68.5% females; the average age was 41.5 years. The average initial weight was 126 kg. The initial BMI at implantation of the gastric balloon was 42.5 kg/m2. The implantation of the prosthesis was uncomplicated in all cases. Average weight loss was 20.75 kg or 7.05 BMI points, respectively.

Die Adipositaschirurgie bei Kindern und Jugendlichen findet in Deutschland bisher keine breite Akzeptanz, obwohl es auch bei uns zahlreiche Patienten gibt, die ihr Gewicht trotz intensiver Therapien nicht dauerhaft reduzieren kÖnnen. Wie auch bei Erwachsenen weisen viele dieser Kinder und Jugendlichen bereits eine oder mehrere metabolische und/oder kardiovaskulÄre VerÄnderungen des metabolischen Syndroms auf. Der folgende Artikel vergleicht die nationalen mit den internationalen Erfahrungen hinsichtlich der Leitlinien, Operationstechniken und Ergebnisse. Dabei zeigt sich, dass es in Deutschland bisher weder eine einheitliche Leitlinie noch ein zentrales Register fÜr Adipositaschirurgie bei Kindern und Jugendlichen gibt. Internationalgelten die Empfehlungen der Bariatric Scientific Collaborative Group (BSCG) auch fÜr Kinder als Standard. Operativ finden sich in der Literatur im Wesentlichen der Roux-Y-Magenbypass und das Magenband, in letzter Zeit auch die Schlauchmagenbildung (sleeve gastrectomy). Diese werden insbesondere in den USA in designierten pÄdiatrischen Zentren durchgefÜhrt. Deren Erfolgs- und Komplikationsraten scheinen Ähnlich wie bei Erwachsenen zu sein. Allerdings bleibt dabei vÖllig offen, wie diese Ergebnisse angesichts der sehr viel lÄngeren Lebenserwartung zu beurteilen sein werden. Als Konsequenz ergibt sich, dass fÜr Kinder und Jugendliche mit morbider Adipositas a) spezielle Zentren mit dem gesamten Behandlungsspektrum etabliert werden sollten, b) Leitlinien fÜr diese Adipositaschirurgie definiert werden mÜssen und c)eine langfristige Nachsorge aller Patienten im Rahmen einerzentralen Studie gewÄhrleistet sein mÜsste, um Erfahrungen fÜr die Zukunft zu generieren. Bariatric Surgery for Morbid Obesity in Childhood and Adolescence: Where Do We Stand in 2008? Bariatric surgery for children and adolescents with morbid obesity has not gained broad acceptance in Germany yet. Nevertheless, these children often fail to reduce weight despite intensive weight loss programmes and suffer from an associate metabolic syndrome, just like adults. Thus, bariatric surgery may be a favourable option. The present article compares national and international experiences concerning guidelines, surgical procedures, and results. It becomes obvious that Germany has neither specific guidelines for children and adolescents nor a central registry. Internationally, the recommendation from the Bariatric Scientific Collaborative Group (BSCG) should be taken as the standard. As in adults, most surgeons performRoux-Y gastric bypass or gastric banding. Additionally, sleeve gastrectomy is gaining some popularity. These procedures are performed in designated pediatric centres especially in the US. Their success and complication rates are similar to those found in adults. The overall long-term consequences, however, remain unclear. Thus, for bariatric surgery in children and adolescents it may be concluded that a) these patients should be treated in designated centres that offer the full range of therapeutic options, b) specific guidelines should be established, especially in Germany, and c) a long-term postoperative study of all patients is necessary to collect all data and refine the techniques used.

The most common morphological changes in 485 of our ambulatory patients were found on external examination of the anal region (46%). These changes included erosions, fissur and eczema. Regarding the symptoms the predominant complaints were itching and burning in 42.1%. Anal hygiene after defaecation was most commonly done with dry toilet-paper (55%). A change in anal hygiene after defaecation relieves symptoms: By changing from water to moist toilet paper in 9%, from dry toilet paper to moist toilet paper in 30%, from moist toilet paper to water in 32%, an from dry toilet paper to water in 60%. These results confirm known facts regarding the influences of conserving agents an printing materials in dry (often recycled) and moist toilet papers on the skin. These side-effects to be even more pronounced in the compromised skin and suggest that anal hygiene should be done with water only.

Erythrocytes did not influence the harvesting procedure or the paper strip counting method in a liquid scintillation counter using the whole blood assay of lymphocyte transformation test. The leucocyte-erythrocyte-ratio influences the blastogenesis in vitro. Only 1--2 ml of peripheral blood are necessary to proof lymphocyte reactivity to mitogens or antigens. The storage of the blood is possible over a period of 24 hours (4 degrees C) if the absolute lymphocytes count remains constant.

Serum IgE concentrations, determined by two commercial kits (Phadebas RIST and PRIST) in 93 adult controls resulted in a geometrical mean value of 47 (RIST) and 35 U/ml (PRIST) respectively within a + 2 SD value of 195 and 331 U/ml respectively. The difference between the separated random samples is statistically significant (t = 3.79; p less than 1%), but the correlation is still fairly satisfactory (r = 0.79). In the lower regions the IgE values with RIST are as a rule a little higher than with the PRIST method. Surprisingly, one patient showed an extremely low IgE value (7 U/ml) with PRIST, but a considerably higher one (530 U/ml) with RIST. Such marked differences are found occasionally in the literature: heterophile antibodies against bovine gammaglobulin are regarded as responsible for the interference in the Sephadex system of RIST. As the reproducibility of the IgE determinations with the PRIST method is excellent (the correlation coefficient for two PRIST determinations was r = 0.93), and as PRIST allows much lower IgE estimates, this procedure should be given preference, particularly in pediatric patients. On the other hand, RIST must be used for the determination of extremely high values, as for instance in patients with severe atopic dermatitis or with parasitic infestations. In fact they can no longer be exactly evaluated by PRIST. Quality control of IgE serum determinations among twelve randomly chosen laboratories in Switzerland in 5 patients was satisfactory, with one exception. In the case of extremely high values, however, only a few laboratories try to determine the exact value. Indications of more than 500 U/ml were considered sufficient, with actual values amounting to 12,500 U/ml. It is also advisable to standardize the serum dilutions, the use of reference serum and the price. Finally, the indications for IgE determination are discussed. It is considered to have an important bearing on the differential diagnosis and prognosis of atopic diseases in infants and children.