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The emergence of Adapted Physical Activity (APA) in the medical world is studied through the lens of its normative references within two medical specialties characterized by their precursory and complementary roles: cardiology, as practiced in university hospitals, and diabetology, in health and social service networks. In this context, a normative tension appears between the aim of adapting the human organism to a controlled effort and the aim of developing patient’s self-normativity (adaptation versus adaptativity [Canguilhem, 1966]). This tension highlights the double challenge of constructing professional territory in APA while fashioning contemporary forms of governing bodily conduct.

Résumé De nouveaux antidiabétiques sont régulièrement mis à la disposition des prescripteurs, en particulier des agonistes du récepteur du Glucagon-like peptide -1 (GLP-1). En 2016, un nouveau modulateur sélectif des récepteurs aux estrogènes, agissant comme un antagoniste du récepteur de l’estrogène au niveau de l’utérus, qui permet de réduire considérablement le risque induit par les estrogènes d’hyperplasie de l’endomètre chez les femmes non hystérectomisées, a également été mis sur le marché. Summary New anti-diabetic drugs are regularly becoming available, in particular Glucagon-like peptide-1 (GLP-1) receptor agonists. In 2016, a new selective oestrogen receptor modulator, acting in the uterus as an oestrogen receptor antagonist, which considerably reduces the risk caused by oestrogen of endometrial hyperplasia in women with an intact uterus, have also arrived on the market. [ABSTRACT FROM AUTHOR]

The present chapter deals with the contribution of Professor Paul A. Bastenie, as Chief of the Department of Medicine of the Saint-Pierre Hospital and Director of the Laboratory of Experimental Medicine at Brussels Free University, in the field of diabetes with emphasis on the role of insulin in glucose homeostasis. The knowledge and experimental work under consideration is covering the period from 1955 to 1974. They entail not only three treatises contributed by Bastenie but also fundamental and clinical investigations, such as those presented in eight doctoral dissertations submitted for aggregation examination at Brussels Free University. These theses are dealing with the measurement of glucose assimilation (V. Conard), the measurement of insulin activity in men (J.R.M. Franckson), the mechanisms of action of hypoglycemic drugs (R. Bellens), the study of energy metabolism in children (H. Loeb), the study of insulin secretion in vitro (W. Malaisse), the distribution of insulin in body fluids as influenced by the permeability and structure of blood capillaries (E. Rasio), the regulation of the extra-hepatic metabolism of ketone bodies in anesthetized dogs (E.O. Balasse) and the use of radioiodinated insulin as tracers in biology (H.A. Ooms).