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1. Facteurs entomologiques d’émergence des arboviroses

Author

Frédéric Simard, David Roiz, Y. Perrin, F. Jourdain, Christophe Paupy, K. Grucker, Centre national d'expertise des vecteurs, Montpellier (CNEV), Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Diversity, ecology, evolution & Adaptation of arthropod vectors (MIVEGEC-DEEVA), Evolution des Systèmes Vectoriels (ESV), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), and Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut de Recherche pour le Développement (IRD [France-Sud])-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)

Subjects
Arbovirus Infections, viruses, [SDV]Life Sciences [q-bio], 030231 tropical medicine, Clinical Biochemistry, Context (language use), medicine.disease_cause, Arbovirus, Dengue fever, 03 medical and health sciences, 0302 clinical medicine, Environmental health, medicine, Chikungunya, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, Aedes, 0303 health sciences, biology, Transmission (medicine), Biochemistry (medical), Hematology, biology.organism_classification, medicine.disease, 3. Good health, Geography, Risk assessment
Abstract

Arboviruses - viruses transmitted by haematophagous arthropods - are responsible for febrile syndromes, which sometimes include haemorrhagic or neurological symptoms. Human activities have facilitated the emergence of these originally zoonotic viruses and the domestication and spread throughout the world of their major vectors. The last decade has seen significant changes in the epidemiology of arboviruses transmitted by mosquitoes of the genus Aedes, particularly in relation to the intercontinental spread of Aedes albopictus. Here, we address the epidemiological consequences of the invasion by this species into Central Africa and Europe in a context of viral globalization. The risk of transmission in these areas is influenced by virus-vector adaptation phenomena as well as environmental phenomena including climate. Faced with these new risks, it is essential to develop competences in entomological and virological surveillance, risk assessment and forecasting of epidemic risk in order to develop strategies for the prevention and control of epidemics.

Published
2015

2. [Food allergy in children: anything new in its management?]

Author

J, Wassenberg, M, Hofer, Y, Perrin, and P, Eigenmann

Subjects
Risk Factors, Decision Trees, Humans, Child, Anaphylaxis, Food Hypersensitivity
Abstract

The prevalence of food allergy in children is increasing, in particular in its most severe presentation, i.e. anaphylaxis. Food allergy has an important impact on children's and their parent's quality of life, because of the fear of accidental ingestion and limitations of social activities. Quality of life questionnaires adapted to food allergy are now available, as well as new diagnostic procedures using recombinant technology. Their interpretation and their clinical correlation remain difficult, especially in children, in the absence of references values. Various oral and subcutaneous immunotherapy strategies are currently under evaluation, using modified or native allergens.

Published
2011

3. [Aedes albopictus in metropolitan France]

Author

P, Delaunay, T, Hubiche, V, Blanc, Y, Perrin, P, Marty, and P, Del Giudice

Subjects
Population Density, Aedes, Urban Health, Animals, Humans, France, Arbovirus Infections, Disease Vectors, Arboviruses
Published
2011

4. [Drug interaction computer programs: which choice?]

Author

Y, Perrin, Th, Buclin, and J, Biollaz

Subjects
Benchmarking, Databases, Factual, Drug Information Services, Adverse Drug Reaction Reporting Systems, Humans, Reproducibility of Results, Drug Interactions, Software, Switzerland
Abstract

Adverse drug reactions represent a partly preventable cause of morbidity. Computer-based tools may be useful for the prevention of those events resulting from drug interactions. While several such tools are currently available to practitioners, they have rarely been compared regarding their performances and limits. This article presents a benchmark evaluation of seven drug interaction databases which may be elected by physicians or pharmacists as an aid to prescription on a regular basis. None of the databases tested appears to be perfect, and the systems vary in their overall completeness and ease of use.

Published
2004

5. Rajeunissement de clones matures d'Hevea brasiliensis (Muell. Arg.) par microgreffage in vitro

Author

Ludovic Lardet, Marc-Philippe Carron, Y. Perrin, and Frank Enjalric

Subjects
clone, Culture in vitro, Budding, Euphorbiaceae, Organogenesis, Plant Science, Horticulture, Biology, biology.organism_classification, F30 - Génétique et amélioration des plantes, Hevea brasiliensis, Micropropagation, F02 - Multiplication végétative des plantes, Shoot, Botany, Rootstock, Agronomy and Crop Science, Explant culture, Greffage
Abstract

L'application à deux clones matures d'Hevea brasiliensis (Mull. Arg.), IRCA 18 et PB235, de la technique de microgreffage d'apex sur des plantules âgées de trois semaines germées in vitro permet le microbouturage de ces clones. Lorsqu'il est effectué à partir d'explants nodaux ou d'extrémités de pousses prélevées sur les greffons développés in vitro sur les porte-greffes, le microbouturage du matériel clonal microgreffé n'est pas possible. De tels explants sont en effet inaptes à reprendre une activité caulogène après leur isolement. Ce problème est surmonté par l'utilisation d'explants mixtes, constitués d'une partie du porte-greffe en contact avec le milieu de culture et du greffon clonal à partir duquel se développent régulièrement des pousses axillaires tout au long des cycles de culture. Les aptitudes au bourgeonnement et au développement de pousses au cours des cycles de culture ont été comparés entre les explants mixtes issus de microgreffes, les explants nodaux d'individus juvéniles et les explants nodaux des clones matures non traités. Cette comparaison révèle un effet très positif de l'application du microgreffage sur l'aptitude des clones IRCA 18 et PB 235 à la caulogenèse in vitro. En outre, les pousses produites par les explants clonaux issus des microgreffes ont une aptitude à l'enracinement identique à celles des pousses produites par les explants issus d'individus juvéniles [résumé d'auteur]

Published
1994

6. Contribution à l'élevage de l'escargot Petit-gris : Helix aspersa Müller (Mollusque Gastéropode Pulmoné Stylommatophore). III. - Elevage mixte (reproduction en bâtiment contrôlé et engraissement en parc extérieur) : activité des individus et évolution de la population juvénile selon la charge biotique du parc

Author

E. Perrin, J.C. Bonnet, J. Daguzan, H. Rouet, Y. Perrin, and Revues Inra, Import

Subjects
Animal Science and Zoology, Biology, [SDV.SA.ZOO] Life Sciences [q-bio]/Agricultural sciences/Zootechny, ComputingMilieux_MISCELLANEOUS
Published
1985

7. [Epidemic of autochthonous hepatic and intestinal amebiasis in a place near Grenoble]

Author

P, Ambroise-Thomas, A, Goullier, R, Grillot, D, Lascaud, L, Rivoire, and Y, Perrin

Subjects
Feces, Entamoebiasis, Metronidazole, Entamoeba histolytica, Water Pollution, Dysentery, Amebic, Liver Abscess, Amebic, Humans, France
Abstract

We had the opportunity of studying an epidemic of autochthonous amoebiasis occurring in the autumn of 1974 in a small town of 4000 inhabitants 30 km from Grenoble. Attention was originally attracted by the occurrence in this town of two cases of hepatic amoebiasis and one of intestinal amoebiasis identified by rectoscopy. Systematic investigations (coproctic examinations and serological tests for amoebiasis by indirect antibody fluorescence) were then carried out on everyone in the locality with digestive disorders which were possibly referable to amoebiasis, and on the other members of their families. A total number of 148 coproctic examinations were made and in two cases revealed the presence of vegetative forms of Entamoeba histolytica. In both cases the infestation provoked few symptoms (asthenia, vague abdominal discomfort, intermittent and apparently banal diarrhoea). On the other hand 20 out of 94 serological tests revealed positive results, 14 of which were equal to or greater than a titre of 1/100, a level at which all risks of non-specificity are virtually ruled out under our experimental conditions. Material reasons made it impossible to subject these cases to repeated faecal checks, but in two of them at least the rectoscopic appearances were very suggestive of subacute intestinal amoebiasis. Moreover, amoebic disease appears to be well confirmed by the results obtained among the patients as a whole by treatment with Metroinidazole. A variety of hypotheses on the origin of this epidemic have been put forward and then abandoned (market garden produce, receipt by certain families of exotic frut from overseas). In actual fact water seems to be the point of departure, for, although specimens of water taken at 7 different levels in the water supply system failed to reveal the presence of a single amoeba, bacteriological analyses during autumn 1974 showed signs of faecal contamination. The locality, which is situated at the foot of the Chartreuse massif, receives its water solely from springs but there is a holiday camp for the staff of an international airline situated above the main water catchment.

Published
1975

9. Les chrétiens en terre d'Islam (VIIe-XIe siècle)

Author

Aillet, Cyrille, Histoire, Archéologie et Littératures des mondes chrétiens et musulmans médiévaux (CIHAM), École normale supérieure de Lyon (ENS de Lyon)-Université Lumière - Lyon 2 (UL2)-École des hautes études en sciences sociales (EHESS)-Université Jean Moulin - Lyon 3 (UJML), Université de Lyon-Université de Lyon-Avignon Université (AU)-Centre National de la Recherche Scientifique (CNRS), J.-R. Armogathe, P. Montaubin, M.-Y. Perrin, École normale supérieure - Lyon (ENS Lyon)-Université Lumière - Lyon 2 (UL2)-École des hautes études en sciences sociales (EHESS)-Université Jean Moulin - Lyon 3 (UJML), Aillet, Cyrille, and J.-R. Armogathe, P. Montaubin, M.-Y. Perrin

Subjects
dhimma, Christianisme en terre d'Islam, relations islamo-chrétiennes, [SHS.HIST] Humanities and Social Sciences/History, Christian-Muslim relations, arabization, islamisation, Christianity in Islamic lands, arabisation, [SHS.HIST]Humanities and Social Sciences/History, islamization
Published
2010

12. Du remploi des statues au remploi des bâtiments publics à Athènes à l'époque hellénistique

Author

Perrin Saminadayar, Eric, Centre de Recherches Interdisciplinaires en Sciences humaines et Sociales de Montpellier (CRISES), Université Paul-Valéry - Montpellier 3 (UPVM), Y. Perrin, and des publications scientifiques, Base

Subjects
[SHS.HIST] Humanities and Social Sciences/History, [SHS.HIST]Humanities and Social Sciences/History, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2009

13. Les cornes de Cipus

Author

Guillaumin , Jean-Yves, Institut des Sciences et Techniques de l'Antiquité - UFC ( ISTA ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), F. Galtier et Y. Perrin, Institut des Sciences et Techniques de l'Antiquité - UFC (UR 4011) (ISTA), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), and Institut des Sciences et Techniques de l'Antiquité - UFC (EA 4011) (ISTA)

Subjects
[ SHS.CLASS ] Humanities and Social Sciences/Classical studies, [SHS.CLASS]Humanities and Social Sciences/Classical studies
Published
2008

14. Sculpteurs grecs et commanditaires romains entre Délos, Rome et l’Italie. Aux origines politiques de l’hellénisme néo-attique

Author

Denti, Mario, Laboratoire d’Archéologie et Histoire Merlat (LAHM), Centre de Recherche en Archéologie, Archéosciences, Histoire (CReAAH), Le Mans Université (UM)-Université de Rennes (UR)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Université de Nantes - UFR Histoire, Histoire de l'Art et Archéologie (UFR HHAA), Université de Nantes (UN)-Université de Nantes (UN)-Ministère de la Culture (MC)-Le Mans Université (UM)-Université de Rennes (UR)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Université de Nantes - UFR Histoire, Histoire de l'Art et Archéologie (UFR HHAA), Université de Nantes (UN)-Université de Nantes (UN)-Ministère de la Culture (MC), Université de Rennes 2 (UR2), Le Mans Université (UM)-Université de Rennes (UR)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Ministère de la Culture (MC)-Nantes Université - UFR Histoire, Histoire de l'Art et Archéologie (Nantes Univ - UFR HHAA), Nantes Université - pôle Humanités, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Humanités, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Editions Latomus, and Y. Perrin

Subjects
[SHS]Humanities and Social Sciences
Abstract

International audience

Published
2007

15. Hraban Maur et l'épiscopat de son temps

Author

Bührer-Thierry, Geneviève, Analyse Comparée des Pouvoirs (ACP), Université Paris-Est Marne-la-Vallée (UPEM), S. Lebecq, M-Y. Perrin, and Buhrer-Thierry, Geneviève

Subjects
[SHS.HIST] Humanities and Social Sciences/History, [SHS.HIST]Humanities and Social Sciences/History, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2006

16. Les figures de l'étranger à l'école primaire : quelles perceptions, quelles catégorisations, quelles stigmatisations

Author

Chevalier, Dominique, Admin, HAL-UT2, D. Nourrisson coord., Y. Perrin coord., Laboratoire Interdisciplinaire Solidarités, Sociétés, Territoires (LISST), and École des hautes études en sciences sociales (EHESS)-Université Toulouse - Jean Jaurès (UT2J)-Centre National de la Recherche Scientifique (CNRS)-École Nationale Supérieure de Formation de l'Enseignement Agricole de Toulouse-Auzeville (ENSFEA)

Subjects
Intégration sociale, [SHS.GEO] Humanities and Social Sciences/Geography, Population étrangère, Ecole, [SHS.GEO]Humanities and Social Sciences/Geography
Abstract

ISBN 2-86272-356-8

Published
2005

17. Le barbare et l’étranger dans l’Italie méridionale pré-normande (IXe-Xe siècles) : l’Empire à l’épreuve de l’altérité

Author

Peters-Custot, Annick, Centre de recherches en histoire internationale et Atlantique - EA 1163 (CRHIA), Université de La Rochelle (ULR)-Université de Nantes - UFR Histoire, Histoire de l'Art et Archéologie (UFR HHAA), Université de Nantes (UN)-Université de Nantes (UN), D. Nourrisson et Y. Perrin, Université de Nantes - UFR Histoire, Histoire de l'Art et Archéologie (UFR HHAA), and Université de Nantes (UN)-Université de Nantes (UN)-Université de La Rochelle (ULR)

Subjects
[SHS.HIST]Humanities and Social Sciences/History, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2004

18. [Entomological factors of arboviruses emergences].

Author

Jourdain F, Roiz D, Perrin Y, Grucker K, Simard F, and Paupy C

Subjects
Adaptation, Physiological, Africa, Central epidemiology, Animals, Arbovirus Infections epidemiology, Arbovirus Infections prevention & control, Climate, Communicable Diseases, Emerging epidemiology, Communicable Diseases, Emerging virology, Ecosystem, Epidemics prevention & control, Europe epidemiology, Humans, Insect Bites and Stings epidemiology, Population Surveillance, Travel, Aedes virology, Arbovirus Infections transmission, Arboviruses physiology, Communicable Diseases, Emerging transmission, Insect Bites and Stings virology, Insect Vectors virology
Abstract

Arboviruses - viruses transmitted by haematophagous arthropods - are responsible for febrile syndromes, which sometimes include haemorrhagic or neurological symptoms. Human activities have facilitated the emergence of these originally zoonotic viruses and the domestication and spread throughout the world of their major vectors. The last decade has seen significant changes in the epidemiology of arboviruses transmitted by mosquitoes of the genus Aedes, particularly in relation to the intercontinental spread of Aedes albopictus. Here, we address the epidemiological consequences of the invasion by this species into Central Africa and Europe in a context of viral globalization. The risk of transmission in these areas is influenced by virus-vector adaptation phenomena as well as environmental phenomena including climate. Faced with these new risks, it is essential to develop competences in entomological and virological surveillance, risk assessment and forecasting of epidemic risk in order to develop strategies for the prevention and control of epidemics., (Copyright © 2015 Elsevier Masson SAS. All rights reserved.)

Published
2015
Full Text
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19. [Aedes albopictus in metropolitan France].

Author

Delaunay P, Hubiche T, Blanc V, Perrin Y, Marty P, and Del Giudice P

Subjects
Animals, Arbovirus Infections transmission, Arboviruses, Disease Vectors, France, Humans, Population Density, Urban Health, Aedes virology
Published
2012
Full Text
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20. [Food allergy in children: anything new in its management?].

Author

Wassenberg J, Hofer M, Perrin Y, and Eigenmann P

Subjects
Anaphylaxis prevention & control, Child, Humans, Risk Factors, Decision Trees, Food Hypersensitivity therapy
Abstract

The prevalence of food allergy in children is increasing, in particular in its most severe presentation, i.e. anaphylaxis. Food allergy has an important impact on children's and their parent's quality of life, because of the fear of accidental ingestion and limitations of social activities. Quality of life questionnaires adapted to food allergy are now available, as well as new diagnostic procedures using recombinant technology. Their interpretation and their clinical correlation remain difficult, especially in children, in the absence of references values. Various oral and subcutaneous immunotherapy strategies are currently under evaluation, using modified or native allergens.

Published
2011

21. [Drug interaction computer programs: which choice?].

Author

Perrin Y, Buclin T, and Biollaz J

Subjects
Adverse Drug Reaction Reporting Systems standards, Benchmarking classification, Benchmarking standards, Databases, Factual standards, Drug Information Services standards, Humans, Reproducibility of Results, Software classification, Software standards, Switzerland, Adverse Drug Reaction Reporting Systems classification, Databases, Factual classification, Drug Information Services classification, Drug Interactions
Abstract

Adverse drug reactions represent a partly preventable cause of morbidity. Computer-based tools may be useful for the prevention of those events resulting from drug interactions. While several such tools are currently available to practitioners, they have rarely been compared regarding their performances and limits. This article presents a benchmark evaluation of seven drug interaction databases which may be elected by physicians or pharmacists as an aid to prescription on a regular basis. None of the databases tested appears to be perfect, and the systems vary in their overall completeness and ease of use.

Published
2004
Full Text
View/download PDF

22. [Epidemic of autochthonous hepatic and intestinal amebiasis in a place near Grenoble].

Author

Ambroise-Thomas P, Goullier A, Grillot R, Lascaud D, Rivoire L, and Perrin Y

Subjects
Dysentery, Amebic parasitology, Entamoeba histolytica isolation & purification, Entamoebiasis drug therapy, Feces parasitology, France, Humans, Liver Abscess, Amebic parasitology, Metronidazole therapeutic use, Water Pollution, Dysentery, Amebic epidemiology, Liver Abscess, Amebic epidemiology
Abstract

We had the opportunity of studying an epidemic of autochthonous amoebiasis occurring in the autumn of 1974 in a small town of 4000 inhabitants 30 km from Grenoble. Attention was originally attracted by the occurrence in this town of two cases of hepatic amoebiasis and one of intestinal amoebiasis identified by rectoscopy. Systematic investigations (coproctic examinations and serological tests for amoebiasis by indirect antibody fluorescence) were then carried out on everyone in the locality with digestive disorders which were possibly referable to amoebiasis, and on the other members of their families. A total number of 148 coproctic examinations were made and in two cases revealed the presence of vegetative forms of Entamoeba histolytica. In both cases the infestation provoked few symptoms (asthenia, vague abdominal discomfort, intermittent and apparently banal diarrhoea). On the other hand 20 out of 94 serological tests revealed positive results, 14 of which were equal to or greater than a titre of 1/100, a level at which all risks of non-specificity are virtually ruled out under our experimental conditions. Material reasons made it impossible to subject these cases to repeated faecal checks, but in two of them at least the rectoscopic appearances were very suggestive of subacute intestinal amoebiasis. Moreover, amoebic disease appears to be well confirmed by the results obtained among the patients as a whole by treatment with Metroinidazole. A variety of hypotheses on the origin of this epidemic have been put forward and then abandoned (market garden produce, receipt by certain families of exotic frut from overseas). In actual fact water seems to be the point of departure, for, although specimens of water taken at 7 different levels in the water supply system failed to reveal the presence of a single amoeba, bacteriological analyses during autumn 1974 showed signs of faecal contamination. The locality, which is situated at the foot of the Chartreuse massif, receives its water solely from springs but there is a holiday camp for the staff of an international airline situated above the main water catchment.

Published
1975

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