1. [Stabilization and function of liposomes].
- Author
-
Rosilio V, Sunamoto J, Puisieux F, Albrecht G, and Baszkin A
- Subjects
- Blood Platelets chemistry, Blood Proteins administration & dosage, Drug Carriers, Drug Stability, Erythrocytes chemistry, In Vitro Techniques, Polysaccharides metabolism, Liposomes metabolism
- Abstract
Liposomes stability can be improved by covering them with polysaccharide derivatives. The anchoring mechanism of these derivatives into the lipid membrane has been studied and explained. In order to improve liposome specificity, protein transfer from erythrocytes and platelets into liposome membrane has been carried out. The effect of a newly developed phospholipid, DDPC, on the efficiency and the selectivity of protein transfer is reported.
- Published
- 1992