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1. [Protection of mice by trehalose dimycolate against lethal infection by Trypanosoma cruzi].

Author

Leon LL, Queiroz-Cruz M, Galvao-Castro B, Soares GH, Lima AO, and Lederer E

Subjects
Animals, Mice, Mice, Inbred Strains, Chagas Disease prevention & control, Cord Factors therapeutic use, Glycolipids therapeutic use
Abstract

Four weekly injections of 50 micrograms of trehalose dimycolate (TDM) in FIA protect 40% of the Mice against a lethal infection by Trypanosoma cruzi; under the same conditions MDP (muramyldipeptide) has only a very slight effect.

Published
1983

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