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2 results on '"Schreiber Y"'

1. Polymorphisme des HLA loci de classe l, HL A-A, -B et -C, dans la population Mandenka du Sénégal Oriental (Polymorphism of HLA class I loci HLA-A, -B, -C, in the Mandenka population from eastern Senegal)

Author

Dard, Patricia Nathalie, Schreiber, Y., Excoffier, Laurent Georges Louis, Sanchez-Mazas, Alicia, Shi-Isaac, X., Epelbouin, A., Langaney, André, and Jeannet, Michel

Subjects
Allele, Phenotype, Human genetics, Senegal Polymorphism, ddc:599.9, Mandenka
Abstract

A sample of 162 Mandenkalu from Eastern Senegal has been typed for three HLA class I loci: HLA-A, -B and -C. The Mandenka population presents a very high genetic variability with 15 alleles for locus A, 24 alleles for locus B, and at least 8 alleles for locus C. The calculated heterozygosities for the three loci A, B, and C are respectively 0.884, 0.944 and 0.829. The Mandenkalu allelic frequencies are close to that found in other sub-Saharan populations. They show, however, some peculiarities like the occurrence of the Bw 56 allele and the high frequencies of both B5 and B35.

Published
1992

2. [Polymorphism of HLA class I loci HLA-A, -B, -C, in the Mandenka population from eastern Senegal].

Author

Dard P, Schreiber Y, Excoffier L, Sanchez-Mazas A, Shi-Isaac X, Epelbouin A, Langaney A, and Jeannet M

Subjects
Alleles, Chi-Square Distribution, Heterozygote, Humans, Phenotype, Senegal epidemiology, Genes, MHC Class I genetics, HLA-A Antigens genetics, HLA-B Antigens genetics, HLA-C Antigens genetics, Polymorphism, Genetic genetics
Abstract

A sample of 162 Mandenkalu from Eastern Senegal has been typed for three HLA class I loci: HLA-A, -B and -C. The Mandenka population presents a very high genetic variability with 15 alleles for locus A, 24 alleles for locus B, and at least 8 alleles for locus C. The calculated heterozygosities for the three loci A, B, and C are respectively 0.884, 0.944 and 0.829. The Mandenkalu allelic frequencies are close to that found in other sub-Saharan populations. They show, however, some peculiarities like the occurrence of the Bw 56 allele and the high frequencies of both B5 and B35.

Published
1992

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