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Dys4ia is an autobiographical video game created by Anna Anthropy, dealing with gender dysphoria. The subject treated, as well as the approach of the writing of the lived experience in video game, make this creation an atypical case at the crossroads of several subversive tendencies regard to the media. A technical and aesthetic analysis makes it possible to identify forms of criticism and militant activity against certain standards of industrial creation. The game can be studied to specify how the experience is autobiographical and how the tools are used. An approach to writing the game as an observation of the tensions between the action and the environment is proposed.

Organization of the genic pool of Vigna unguiculata (L.) Walp. : crosses between the wild and cultivated forms of cowpea. Cowpea (Vigna unguiculata (L.) Walp.) gene pool organization is studied on the basis of intra-specific crossing between cultivated (cv-gr. Unguiculata, cv-gr. Biflora) and wild forms of the species (var. spontanea, subsp. alba, subsp. stenophylla, subsp. pawekiae, subsp. baoulensis). The rate of crosses success, the rate of the obtained pods fruitfulness and the pollinic fertility of the hybrids F1 varied according to the wild taxa used. The highest rate of success was obtained for the crossings between cultivated and annual inbred form (40-79,3%). This result confirms that var. spontanea is genetically closer to the cultivated forms than the other wild forms. Crosses between cultivated and wild allo-autogamous forms gave intermediate rates of success (17,8-57,9%) and a significant reduction of the pollinic fertility of some hybrids F1. These observations suggest the existence of a genetic divergence between these two groups, however they share the same gene pool. The wild allogamous forms gave the weakest rates of success with the cultivated forms (3,1-40%) showing that they are genetically more distant of these last, compared to the other wild groups. The rates of crosses success are particularly weaker when the wild form subsp. baoulensis is crossed with the cultivated forms.

At the end of 2008, Saft has designed the VES16 cell [1], a new Li-ion cell aiming to address Low Earth Orbit (LEO) satellite market. In the frame of ESA GSTP 5.2 activity, Saft has then developed and successfully qualified [2] a range of batteries based on the VES16 cell and its autonomous Simplified Balancing System (SBS), targeting both LEO and Geostationary Earth Orbit (GEO) missions The very good performance of the VES16 cell demonstrated in GEO mission cycling configuration allows now Saft to propose it on small geostationary spacecraft with typical power lower than 10kW, offering a simpler, autonomous and competitive solution compared to Saft high capacity cells solutions with VES180 qualified on several telecommunication spacecraft. This paper will present the design of the VES16, its performance for GEO mission, the configuration of batteries based on this cell, with their benefit and drawbacks, and will detail two current GEO applications using VES16 batteries.

In the frame of an ESA GSTP 5.2 activity (contract 4000105105), the qualification and life testing of a Saft range of Li-ion batteries based on VES16 cells and theirs autonomous simplified balancing system (SBS) has been carried out. In this abstract the development, qualification plan and successful results from all various tests conducted on the VES16 qualification battery modules are synthetized. Up to the present time, Saft batteries have been mainly utilizing for space applications high capacity cells, like the 45 Ah VES180 and the 35 Ah VES140 cells, targeting predominantly space missions in Geostationary Earth Orbit (GEO). However following the qualification and commercialization of the Saft 4.5 Ah VES16 cell in October 2011 [1] & [2], Saft has been developing and qualifying in the frame of this ESA GSTP 5.2 contract, VES 16 batteries for space missions, targeting both GEO and Low Earth Orbit (LEO) satellite missions. The electrochemistry of the VES16 cells used for the battery modules under the ESA qualification program is not novel. For VES16 cells, the Saft knowhow from large capacity space cells used for space applications, since SMART 1 mission in 2003, has been tailored for a cell with smaller capacity in order to facilitate the modular philosophy that has been deployed in this battery range.

Aim: To study the appropriateness and conformity to antibiotic prescription guidelines in an emergency department and to assess the factors likely to influence them., Methods: This prospective study included all adult patients visiting the emergency department over a period of 100 days and receiving antibiotic treatment. Two independent specialists in infectious disease assessed the appropriateness of the indications and the treatment's conformity with good practice guidelines. We also studied patient's status 7 days after initiation of antibiotic treatment, duration of hospitalization and any treatment changes., Results: The study included 211 patients, 47% of them men. Prescriptions were appropriate in 53% of cases and in accordance with guidelines in 34%. Half of all prescriptions were related to urinary tract or pulmonary infections. Four antibiotic families accounted for 88% of prescriptions. Prescription errors were related to multidrug treatments, intravenous drugs, and inappropriate antibiotic families. More than half (56%) of the patients were admitted, and 70% of these remained in the hospital more than one week. Duration of treatment was inappropriate for 31% of the patients not admitted. In all, 44% of the antibiotic prescriptions ordered in the emergency department were later modified., Conclusion: Multidisciplinary work is essential in improving the quality of antibiotic prescriptions in an emergency department.

At the start of the eighties, in the wake of the good results obtained with aspirin in secondary prevention, two studies were launched aimed at testing the effect of aspirin on the primary prevention of myocardial infarction. The results published in 1988 and 1989 were divergent: the study conducted by British doctors showed no benefit with aspirin, that conducted by American doctors showed a very distinct benefit concerning myocardial infarction but no advantage for cerebral vascular accidents. Besides, in both studies an additional risk of haemorrhagic cerebral vascular accident was described. Methodological reasons were the origin of these facts, but it resulted in a certain confusion as to the practical conduct to adopt. Ten years later it is much more clear after the publication of three supplementary trials. The benefits of aspirin in terms of prevention of myocardial infarction are certain and considerable, at the price of a haemorrhagic risk equally certain but moderate. On the other hand, questions remain concerning the preventive effect of aspirin on cerebral vascular accidents and also on the expected benefits in the female sex. In practice, the prescription of aspirin with the objective of primary prevention must take into account the absolute benefit which can be expected. This is a function of the individual absolute risk before treatment which therefore signifies an evaluation based on the risk factors. Only subjects exposed to a substantial risk before treatment are likely to benefit from aspirin. For the others, the risks linked with aspirin could counterbalance its preventive advantages.

Pigmented villonodular synovitis is a rare benign tumor. The high rate or recurrence after surgery exposes the risk of non-conservative or non-functional treatment. External irradiation of post-surgical residual disease seems to be useful for the prevention of relapse and conservation with a good functional result. We report a clinical observation of a case with a diffuse type of pigmented villonodular synovitis of the ankle, operated on three times, and then treated by external irradiation. The published results in terms of response and functional prognosis of 14 cases of multi-recurrent villonodular synovitis treated by irradiation seem to confirm this therapeutic option.