1. Intérêt diagnostique du Test Combiné du Quadriceps dans la Sclérose Latérale Amyotrophique : étude de cohorte
- Author
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Desmaison, Annaïck, Faculté de Médecine - Clermont-Auvergne (FM - UCA), Université Clermont Auvergne (UCA), and Nathalie Guy
- Subjects
Gold coast criteria ,Motoneurone central ,Facteur pronostique ,Potentiels Évoqués Moteurs ,Amyotrophic lateral sclerosis ,Awaji criteria ,Électroneuromyogramme ,Upper motor neuron ,T-MEP-LL ,Electrophysiological diagnosis ,Triple Simulation Transcrânienne ,Motor evoked potential ,Sclérose Latérale Amyotrophique ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology - Abstract
ObjectiveTo evaluate whether Combined Patellar Tendon Reflex-Motor Evoked Potentials to Lower Limb (T-MEP-LL) is relevant to assess corticospinal function in amyotrophic lateral sclerosis (ALS), in a monocentric retrospective study.MethodsT-MEP-LL was performed on 100 patients with motor neuron disease (MND) and 35 patients with other neurological pathologies, during routine diagnosis explorations. Clinical evaluation of the patients included neurological examination, the revised ALS Functional Rating Scale (ALSFRS-R) and Medical Research Council (MRC) score. Awaji and Gold Coast criteria were determined for each patient. Survival was calculated if death occurred.ResultsT-MEP-LL shows a sensitivity of 66% and a specificity of 68.6% to detect MND. T-MEP-LL was abnormal in 66% of the MND patients and 31.43% of patients with other neurological pathologies (p
- Published
- 2021