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Raised intracranial pressure (ICP) is frequent and associated with poor outcome after severe traumatic brain injury (TBI). Information obtained by ICP monitoring allows early detection of high ICP and goal-directed therapy. There is a large body of clinical evidence showing that protocol driven neurocritical care improves outcomes after TBI. A monitoring method cannot be separated from therapeutic implications, which may have beneficial or deleterious consequences. ICP monitoring and guided therapy are not risk-free. A rational use of ICP as a guide to therapy must take into account of the absolute threshold for treatment, but also of the risk/benefit balance of the used intervention., (Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.)