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1. Biosensors in Biomedical Research: Development and Applications of Gene Chips

Author

Ulrich Certa, Remo Hochstrasser, Hanno Langen, Martin Buess, and Christoph Moroni

Subjects
Chemistry, QD1-999
Abstract

Nucleic-acid hybridisation techniques are a central tool for the genetic analysis of biological systems. Gene chips are complex arrays of recombinant plasmids or oligonucleotides immobilised on a glass chip of only 1 cm2. This technology allows, for the first time, the multiparallel expression-analysis of thousands of genes. Gene chips will be indispensable tools for the upcoming analysis of the human genome, once the entire sequence is known.

Published
1999

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