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The purpose of this study is to focus on the coexistence, during the transmission of the doctrine on the Topics in the early Middle Ages, of two different interpretations: although both emerge from two commentaries on Cicero’s Topics, however, they gave rise to two different readings: the one transmitted by Marius Victorinus (ca. 280-365 AC) who thought the topics almost exclusively in the service of Rhetoric, the other conceived by Boethius (ca. 480-524 AC) who intended to restore the centrality that the Topics had in the Aristotelian Logic, by subordinating the rethorical Topics to dialectical Topics. My conclusion is that the Early Middle Ages can be considered, from an epistemological point of view, as a long boetiana aetas. Although the corpus of Boethius’s logical writings was not yet available until the second half of the 11th century, Boethius’s methodological approach on the Topics somehow continued to support the slow but constant absorption of the topical doctrine into the new Christian sensibility.

INTRODUCTION: scaling up of antiretroviral therapy (ART) to HIV+ pregnant women is crucial for the elimination of HIV infection in children. The aim of this study was to evaluate the feasibility and effectiveness of triple ART for Prevention of Mother-to Child Transmission (PMTCT) in Cameroon. Methods: HIV-positive pregnant women attending the DREAM Centre of Dschang, Cameroon for prenatal care were enrolled in a prospective cohort study, and received ART until the end of breastfeeding or indefinitely if their CD4 count was 350mm3. Infants were evaluated for HIV infection at 1, 6 and 12 months of age. METHODS: HIV-positive pregnant women attending the DREAM Centre of Dschang, Cameroon for prenatal care were enrolled in a prospective cohort study, and received ART until the end of breastfeeding or indefinitely if their CD4 count was 350mm3. Infants were evaluated for HIV infection at 1, 6 and 12 months of age. RESULTS: a total of 298 women were enrolled. Among them, 152 were already on established ART. Women were followed until 6 months after delivery with a retention rate of 92.6%. Eight women died. Those with a CD4 count =350 cells/mm3 during pregnancy had the highest mortality risk (RR 2.53; 95% CL= 1.86-3.44). The HIV transmission rate was 1.2% at 12 months with an HIV free survival of 91%. In the proportional Cox regression analysis, the following factors were positively associated with infant mortality: maternal CD4= 350 cells/mm3, no breastfeeding in the first 6 months of life, weight-for-age z score -2. CONCLUSION: results confirm the feasibility and effectiveness of the implementation of Option B, with very low rates of HIV MTC transmission, and potential benefits to the health of mothers and infants with earlier initiation of ART. Breastfeeding again demonstrates to be highly beneficial for the growth and survival of HIV exposed children.