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Sustainable management of sites affected by past industrial activities in Wallonia: the stakes and the challenges of risk assessment within the framework of the new policy developments on (local) soil pollutions. Risk-based land management is a concept that stands out more and more frequently in soil policies adopted by different European countries, as well as within the framework of the future European directive on soil protection. This concept intends to act as a lever for sustainable solution development in terms of rehabilitation by ensuring the following principles: (1) reduction of risks (human health, ecosystems) allowing sites to be reused safely (concept of fitness for use); (2) prevention of any pollutant dispersion risk (concept of environmental protection); (3) long-term care while minimising the burden of controlling, maintenance and monitoring. These ideas have been taken as backdrop for the Walloon decree on soil remediation and rehabilitation of disused economic activity sites. Risk control has been taken as a key point for any decision related to historically polluted sites. However, to be effective, this option stands out that reliable and efficient methodological tools are available for land evaluation (risk assessment). Three decision-making tools, specifically developed for the intended applications in the Walloon Region, are presented in the paper: (1) a global risk evaluation method allowing ranking of polluted sites; (2) a method to decide, at the end of the first step of the investigation procedure (preliminary soil investigation), whether further investigations are required or not; (3) a methodological procedure to proceed to a detailed risk assessment at the end of the in-depth investigation step. Perspectives are proposed to improve these first tools. It has also been shown that the challenge of sustainable solutions for the management of polluted sites finally depends on answers that will be progressively developed by the scientific community. These have to take into account all aspects of the Walloon context.

The authors report the case of a woman with Sturge-Weber syndrome (oculotrigeminate form) presenting with neovascular glaucoma of abrupt onset during pregnancy. Since medical treatment failed, she underwent a retrobulbar alcoholisation. Three months after delivery, enucleation was performed for esthetic reasons. The enucleated eye showed diffuse choroidal angioma, total retinal detachment and a prepapillary glial proliferation. We discuss this uncommon association.

Presentation of a case of Sipple's syndrome with bilateral malignant pheochromocytoma, bilateral thyroid medullary carcinoma and two parathyroid adenomas. The principal characters of the syndrome, the diagnostic tests, the necessity of a prospective survey of family relatives are discussed.

Medroxyprogesterone acetate (MPA), a potent progestagen, is used as a very efficient contraceptive agent. The method of administration is by a threemonthly or sixmonthly intramuscular injection. The method is particularly convenient when the desired number of children has been reached. Fertility is sometimes reestablished only slowly after stopping the injections. The main side effects are linked to endometrial atrophy (blood loss, amenorrhoea). Other side effects are infrequent and subjective. A controversy has risen over the product, by reference to its effects on beagle dogs. We have reviewed the literature. We also present the characteristics of 313 patients treated during (all together) 8,000 months. These patients belong to a rather poor sample of the population (amongst them many immigrant women), aged about 30, with above average pregnancy and parity rates. We also studied, in 31 patients, serum levels of glucose and lipids, and haemostasis. Side effects and reasons for discontinuing the drug are reported. The Pearl index was 0,75% women-years. There was no average effect on weight, blood tension, glycemia. Triglycerides increased slightly, and there was a discreet activation of coagulation with inhibition of the fibrinolytic activity, but without clinical consequences. We conclude that we can go on prescribing the drug, in view of our study and after reviewing the literature.