1. [Interest of radiotherapy of rectal cancer with synchronous metastases]
- Author
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H, Tournat, V, Vendrely, B, Cherciu, D, Smith, C, Laurent, M, Capdepont, G, Kantor, and J P, Maire
- Subjects
Adult ,Aged, 80 and over ,Male ,Rectal Neoplasms ,Humans ,Female ,Middle Aged ,Neoplasm Metastasis ,Aged - Abstract
There is no consensus about the treatment of rectal tumour when there are synchronous metastases. The interest of radiotherapy is debated.Thirty-seven patients with rectal tumour and synchronous metastases were treated with radiotherapy first between September 1994 and December 2004. We analysed the tolerance, local control, resecability, overall survival of such a therapeutic strategy.The mean follow-up was 30 months. Twenty-four tumors were resecable for both the primary site and the metastases. Thirteen were unresecable at the time of diagnosis. Thirty-three patients were treated with radiochemotherapy, ten with radiotherapy alone. Eighty-six decimal five percent of them had no pelvic symptom six weeks after the treatment. Twenty-one rectal tumours were finally resected. The disease progressed in six cases during the radiotherapy. Surgery of the metastases was possible for 12 patients with tumour initially resecable.Radiochemotherapy is a "tolerable" treatment, in spite of more frequent urinary or digestive side-effects. But, if there is no surgery, palliative effect of radiotherapy is limited.
- Published
- 2007