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4 results on '"Leulliot N"'

1. O.20A - Fond génétique partagé entre la pneumopathie interstitielle diffuse associée à la polyarthrite rhumatoïde et la fibrose pulmonaire idiopathique

Author

Juge, P.A., Borie, R., Kannengiesser, C., Gazal, S., Revy, P., Wemeau-Stervinou, L., Debray, M.P., Ottaviani, S., Marchand-Adam, S., Nathan, N., Thabut, G., Richez, C., Nunes, H., Callebaut, I., Justet, A., Leulliot, N., Bonnefond, A., Salgado, D., Richette, P., Desvignes, J.P., Lioté, H., Froguel, P., Allanore, Y., Sand, O., Dromer, C., Flipo, R.M., Clément, A., Béroud, C., Sibilia, J., Coustet, B., Cottin, V., Boissier, M.C., Wallaert, B., Schaeverbeke, T., Le Moal, F. Dastot, Frazier-Mironer, A., Ménard, C., Soubrier, M., Saindenberg, N., Valeyre, D., Amselem, S., Boileau, C., Crestani, B., and Dieudé, P.

Published
2016
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2. Fond génétique partagé entre la pneumopathie interstitielle diffuse associée à la polyarthrite rhumatoïde et la fibrose pulmonaire idiopathique

Author

Juge, P.A., Borie, R., Kannengiesser, C., Gazal, S., Revy, P., Wemeau-Stervinou, L., Debray, M.P., Ottaviani, S., Marchand-Adam, S., Nathan, N., Thabut, G., Richez, C., Nunes, H., Callebaut, I., Justet, A., Leulliot, N., Bonnefond, A., Salgado, D., Richette, P., Desvignes, J.P., Lioté, H., Froguel, P., Allanore, Y., Sand, O., Dromer, C., Flipo, R.M., Clément, A., Béroud, C., Sibilia, J., Coustet, B., Cottin, V., Boissier, M.C., Wallaert, B., Schaeverbeke, T., Moal, F. Dastot Le, Frazier, A., Ménard, C., Soubrier, M., Saidenberg, N., Valeyre, D., Amselem, S., Boileau, C., Crestani, B., and Dieude, P.

Published
2017
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4. [Ribosomes synthesis at the heart of cell proliferation].

Author

Madru C, Leulliot N, and Lebaron S

Subjects
Animals, Cell Cycle physiology, Cell Division, Humans, Protein Biosynthesis, Cell Proliferation, Ribosomes metabolism, Ribosomes physiology
Abstract

Ribosomes are central to gene expression. Their assembly is a complex and an energy consuming process. Many controls exist to make it possible a fine-tuning of ribosome production adapted to cell needs. In this review, we describe recent advances in the characterisation of the links occurring between ribosome synthesis and cell proliferation control. Defects in ribosome biogenesis directly impede cellular cycle and slow-down proliferation. Among the different factors involved, we could define the 5S particle, a ribosome sub-complex, as a key-regulator of p53 and other tumour suppressors such as pRB. This cross-talk between ribosome neogenesis defects and proliferation and cellular cycle also involves other cell cycle controls such as p14 ARF , SRSF1 or PRAS40 pathways. These data place ribosome synthesis at the heart of cell proliferation and offer new therapeutic strategies against cancer., (© 2017 médecine/sciences – Inserm.)

Published
2017
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