Search

Your search keyword '"Kuhn L"' showing total 4 results
Start Over Author "Kuhn L" Language french
4 results on '"Kuhn L"'

1. The therapeutic contribution of proteomic approaches in cancers

Author

Hamrita, B., Nasr, H. B., Kabbage, M., Hamann, P., Kuhn, L., Guillier, Christelle, Remadi, S., Chaieb, A., Khairi, H., Chouchane, L., Chahed, K., Université de Monastir (Université de Monastir), Centre National de la Recherche Scientifique (CNRS), FLAveur, VIsion et Comportement du consommateur (FLAVIC), Etablissement National d'Enseignement Supérieur Agronomique de Dijon (ENESAD)-Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB), Lab Cytopath, Partenaires INRAE, Hôpital Farhat Hached, Dept Med Genet, Hôpital Erasme [Bruxelles] (ULB), Faculté de Médecine [Bruxelles] (ULB), Université libre de Bruxelles (ULB)-Université libre de Bruxelles (ULB)-Faculté de Médecine [Bruxelles] (ULB), and Université libre de Bruxelles (ULB)-Université libre de Bruxelles (ULB)

Subjects
INFILTRATING DUCTAL CARCINOMA, Proteomics, Tumors markers, IDENTIFICATION, [SDV]Life Sciences [q-bio], MASS-SPECTROMETRY, Two dimensional gel electrophoresis, LUNG-CANCER, RENAL-CELL CARCINOMA, HUMORAL IMMUNE-RESPONSE, HEPATOCELLULAR-CARCINOMA, [SDE]Environmental Sciences, Therapeutic targets, HEAT-SHOCK PROTEINS, BREAST-CANCER, [SDV.BV]Life Sciences [q-bio]/Vegetal Biology, TUMOR-ANTIGEN
Abstract

National audience; Up to now, there are no protein tumor markers with a specificity and sensitivity sufficient to have a utility in prognosis and early diagnosis of cancer. Recent advances in proteomics approaches have led to the identification of novel tumor markers of cancer that may have a utility in screening strategies and treatment. The purpose of the current review is to describe the major advances in cancer proteomics, especially those related to the study of serum biomarkers, immune-related responses (autoantibodies) and alterations in cellular proteins. (C) 2011 Elsevier Masson SAS. All rights reserved.

Published
2011
Full Text
View/download PDF

2. L’apport thérapeutique des approches protéomiques dans les cancers

Author

Hamrita, B., Nasr, H.B., Kabbage, M., Hamann, P., Kuhn, L., Guillier, C., Remadi, S., Chaieb, A., Khairi, H., Chouchane, L., and Chahed, K.

Subjects
*PROTEOMICS, *CANCER diagnosis, *TUMOR markers, *CANCER treatment, *GEL electrophoresis, *PROGNOSIS, *SERUM, *BIOMARKERS, *EARLY diagnosis, *IMMUNE response, *AUTOANTIBODIES
Abstract

Abstract: Up to now, there are no protein tumor markers with a specificity and sensitivity sufficient to have a utility in prognosis and early diagnosis of cancer. Recent advances in proteomics approaches have led to the identification of novel tumor markers of cancer that may have a utility in screening strategies and treatment. The purpose of the current review is to describe the major advances in cancer proteomics, especially those related to the study of serum biomarkers, immune-related responses (autoantibodies) and alterations in cellular proteins. [Copyright &y& Elsevier]

Published
2011
Full Text
View/download PDF

3. [Towards a better knowledge of breast cancer physiopathology: the proteomics approach].

Author

Hamrita B, Ben Nasr H, Hammann P, Kuhn L, Ben Anes A, Dimassi S, Chaieb A, Khairi H, and Chahed K

Subjects
Biomarkers, Tumor analysis, Biomarkers, Tumor metabolism, Biomedical Research methods, Biomedical Research trends, Breast Neoplasms diagnosis, Breast Neoplasms metabolism, Carcinoma diagnosis, Carcinoma metabolism, Female, Humans, Medical Oncology trends, Neoplasm Proteins analysis, Neoplasm Proteins metabolism, Proteome analysis, Proteome metabolism, Breast Neoplasms etiology, Carcinoma etiology, Knowledge, Proteomics methods
Abstract

Breast cancer represents a major public health problem. Approximately one woman in ten is likely to develop a malignant tumor of the breast in their lifetime. The frequency of breast cancer is rising steadily for 20 years and the practical benefits in the diagnosis, prognosis and treatment of this disease are still too limited. Actually, there is no tumor marker with a specificity and sensitivity sufficient to have an utility in clinical and early diagnosis of breast cancer, although, carcinoembryonic antigen (CEA), MUC-1 and CA 15-3 were reported to be useful as markers for monitoring this disease. Thus, proteomics approaches are needed for the discovery and the identification of new protein biomarkers that may allow a better understanding of biological mechanisms of breast tumor development and serve as potential therapeutic targets. This article reviews advances in this field, as well as, the major contribution of these markers in breast pathology, with a focus on their biological characteristics and their clinical and therapeutic involvement.

Published
2012
Full Text
View/download PDF

4. [The therapeutic contribution of proteomic approaches in cancers].

Author

Hamrita B, Nasr HB, Kabbage M, Hamann P, Kuhn L, Guillier C, Remadi S, Chaieb A, Khairi H, Chouchane L, and Chahed K

Subjects
Autoantibodies, Biomarkers, Tumor analysis, Biomarkers, Tumor blood, Humans, Neoplasm Proteins analysis, Neoplasms chemistry, Prognosis, Sensitivity and Specificity, Neoplasms diagnosis, Neoplasms therapy, Proteomics
Abstract

Up to now, there are no protein tumor markers with a specificity and sensitivity sufficient to have a utility in prognosis and early diagnosis of cancer. Recent advances in proteomics approaches have led to the identification of novel tumor markers of cancer that may have a utility in screening strategies and treatment. The purpose of the current review is to describe the major advances in cancer proteomics, especially those related to the study of serum biomarkers, immune-related responses (autoantibodies) and alterations in cellular proteins., (Copyright © 2011 Elsevier Masson SAS. All rights reserved.)

Published
2011
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results