1. [Disseminated histoplasmosis caused by Histoplasma capsulatum with cerebral involvement occurring 13 years after the primary infection].
- Author
-
Bérard H, Astoul P, Frenay C, Cuguillière A, Cho K, and Boutin C
- Subjects
- Antifungal Agents administration & dosage, Antifungal Agents therapeutic use, Brain diagnostic imaging, Fluconazole administration & dosage, Fluconazole therapeutic use, Humans, Ketoconazole administration & dosage, Ketoconazole therapeutic use, Lung Diseases, Fungal diagnosis, Lung Diseases, Fungal drug therapy, Male, Middle Aged, Radiography, Thoracic, Time Factors, Tomography, X-Ray Computed, Brain Diseases diagnosis, Brain Diseases drug therapy, Central Nervous System Fungal Infections diagnosis, Central Nervous System Fungal Infections drug therapy, Histoplasmosis diagnosis, Histoplasmosis drug therapy
- Abstract
A 49-year-old man with disseminated histoplasmosis (pulmonary and central nervous system involvement) successfully treated with ketoconazole and fluconazole combination is reported. Histoplasma capsulatum infection of the central nervous system is extremely rare in France partly because the organism is not endemic. Oral treatment with newer triazoles may be useful for central nervous system histoplasmosis, but additional information is needed to establish their effectiveness.
- Published
- 1999