1. [Association of Kaposi sarcoma--multiple myeloma. A new case]
- Author
-
J D, Cohen, E, Thomas, N, Garnier, I, Hellier, L, Durand, J J, Guilhou, P, Baldet, and F, Blotman
- Subjects
Aged, 80 and over ,Herpesvirus 4, Human ,Cytomegalovirus ,Humans ,Female ,Multiple Myeloma ,Sarcoma, Kaposi ,Aged ,Neoplasm Staging - Abstract
Kaposi's disease is an angiogenic multifocal cancer process that has several forms, namely Mediterranean, African, HIV-associated, and secondary to a preexisting immunodepressive state (hematological disorder, corticosteroid therapy, immunodepressive treatment). Whatever its form, Kaposi's sarcoma is probably associated with a chronic viral human herpes type 8 infection (HHV8).This virus has been implicated in the pathogenesis of multiple myeloma (17 cases recorded to date). In the present study, a further case of Kaposi's sarcoma associated with multiple myeloma has been reported. However, Epstein-Barr virus, cytomegalovirus, hepatitis B and C, HIV and HHV8 serologies were negative. Radiotherapy on the lower limbs was initiated.It is concluded that HHV8 does not appear to play a pathogenic role in cases of multiple myeloma, given the rarity of the association between Kaposi's sarcoma/multiple myeloma/HHV8.
- Published
- 2000