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Résumé: En France, la mortalité globale des patients atteints de carcinome hépatocellulaire (CHC) demeure parmi les plus élevées comparée à celle des autres cancers, principalement en raison d'un diagnostic tardif ne permettant pas l'implémentation de traitements à visée curative. De nouvelles stratégies sont venues récemment enrichir l'arsenal thérapeutique pour les CHC avancés, en première et en seconde ligne. Cependant, ces nouveautés thérapeutiques ne seront pas seules suffisantes pour drastiquement améliorer le pronostic global. Il est aussi essentiel de veiller au respect des recommandations de surveillance, et notamment le délai de six mois entre les imageries de dépistage, afin d'accroître la proportion de patients éligibles à un traitement curatif au moment du diagnostic, et de limiter les délais de prise en charge dans le but ultime d'améliorer la survie globale des patients dans un futur proche. In France, overall mortality of patients with hepatocellular carcinoma (HCC) remains among the highest compared to that of other cancers, mainly due to a late diagnosis precluding the implementation of curative treatments. New drugs have recently been added to the therapeutic options available for advanced CHC, in first and second line. However, these newcomers will not alone be enough to dramatically improve the overall prognosis of HCC. Compliance with surveillance guidelines is critical, in particular the 6-month timeframe between screening imaging, to increase the proportion of patients eligible for curative treatment at the time of diagnosis, and delays in treatment initiation should be avoided with the ultimate goal of improving the overall survival of patients in a near future. [ABSTRACT FROM AUTHOR]

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