19 results on '"Goucha, Rym"'
Search Results
2. Évolution du spectre des néphropathies glomérulaires en Tunisie de 1975 à 2005. Ses rapports avec l’évolution sanitaire et sociale
- Author
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Maϊz, Hédi Ben, Abderrahim, Ezzeddine, Moussa, Fatma Ben, Goucha, Rym, and Karoui, Cyrine
- Published
- 2006
- Full Text
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3. Amylose rénale compliquant l’évolution de colites inflammatoires chroniques
- Author
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Béji, Soumaya, Kaaroud, Hayet, Ben Moussa, Fatma, Goucha, Rym, Abderrahim, Ezzedine, El Younsi, Fethi, and Ben Maïz, Hédi
- Published
- 2004
- Full Text
- View/download PDF
4. Syndrome de Behçet associé à une néphropathie à Ig A.
- Author
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Mahfoudhi, Madiha and Goucha, Rym
- Published
- 2015
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5. [Behçet syndrome associated with IgA nephropathy].
- Author
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Mahfoudhi M and Goucha R
- Subjects
- Adult, Glomerulonephritis, IGA etiology, Humans, Male, Behcet Syndrome physiopathology, Glomerulonephritis, IGA diagnosis
- Published
- 2015
- Full Text
- View/download PDF
6. [Renal AA amyloidosis during Langerhans' cell histiocytosis: case report].
- Author
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Ounissi M, Fouda HD, Hedri H, Boubaker K, Barbouch S, Bacha MM, Goucha R, Abderrahim E, Ben Maiz H, and Kheder A
- Subjects
- Adult, Amyloidosis pathology, Fatal Outcome, Histiocytosis, Langerhans-Cell pathology, Humans, Kidney Diseases pathology, Male, Amyloidosis complications, Histiocytosis, Langerhans-Cell complications, Kidney Diseases complications
- Published
- 2013
7. [Renal abnormalities in ankylosing spondylitis].
- Author
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Samia B, Hazgui F, Abdelghani KB, Hamida FB, Goucha R, Hedri H, Taarit CB, Maiz HB, and Kheder A
- Subjects
- Adolescent, Adult, Aged, Child, Female, Follow-Up Studies, Humans, Kidney Diseases epidemiology, Male, Middle Aged, Prevalence, Prognosis, Retrospective Studies, Risk Factors, Young Adult, Kidney Diseases etiology, Spondylitis, Ankylosing complications
- Abstract
We will study the epidemiologic, clinical, biological, therapeutic, prognostic characteristics and predictive factors of development of nephropathy in ankylosing spondylitis patients. We retrospectively reviewed the medical record of 32 cases with renal involvement among 212 cases of ankylosing spondylitis followed in our service during the period spread out between 1978 and 2006. The renal involvement occurred in all patients a mean of 12 years after the clinical onset of the rheumatic disease. Thirty-two patients presented one or more signs of renal involvement: microscopic hematuria in 22 patients, proteinuria in 23 patients, nephrotic syndrome in 11 patients and decreased renal function in 24 patients (75%). Secondary renal amyloidosis (13 patients), which corresponds to a prevalence of 6,1% and tubulointerstitial nephropathy (7 patients) were the most common cause of renal involvement in ankylosing spondylitis followed by IgA nephropathy (4 patients). Seventeen patients evolved to the end stage renal disease after an average time of 29.8 ± 46 months. The average follow-up of the patients was 4,4 years. By comparing the 32 patients presenting a SPA and renal disease to 88 with SPA and without nephropathy, we detected the predictive factors of occurred of nephropathy: tobacco, intense inflammatory syndrome, sacroileite stage 3 or 4 and presence of column bamboo. The finding of 75% of the patients presented a renal failure at the time of the diagnosis of renal involvement suggests that evidence of renal abnormality involvement should be actively sought in this disease., (Copyright © 2011 Association Société de néphrologie. Published by Elsevier SAS. All rights reserved.)
- Published
- 2012
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8. [Etiologic profile of amyloidosis of the elderly in Tunisia].
- Author
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Ben Abdelghani K, Barbouch S, Ounissi M, Ounissi M, Mahfoudhi M, Ben Moussa F, Goucha R, Turki S, and Kheder A
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- Aged, Aged, 80 and over, Female, Humans, Male, Retrospective Studies, Tunisia, Amyloidosis etiology
- Abstract
Background: The amyloidosis is one of the histologic lesions the most frequently associated to the aging., Aim: To identify the several etiologies of amyloidosis in elderly patients according to immunohistochemical type., Methods: Retrospective study on 10 years, in Internal medicine and Nephrology department in Charles Nicolle Hospital. Tunis. Tunisia. Diagnosis of amyloidosis was retained after histological confirmation with specific colorations, in patients aged 65 years or more at the diagnose of amyloidosis., Results: The study enrolled 51 patients with amyloidosis. In 67% of cases it was AA amyloidosis. The etiology the most frequently observed with this type was the tuberculosis, followed by chronic pulmonary infections. We retained diagnose of non AA amyloidosis in 21% of patients. The multiple myeloma has been the most frequent etiology observed, but no cause was identified at about half of patients. Twelve per cent of amyloidosis were not typed., Conclusion: From our study, we can remark the high predominance of AA amyloidosis, probably because of frequency of tuberculosis which is still high in our country, this is not in accordance with occidental data, were AL amyloidosis and senile amyloidosis predominate in elderly.
- Published
- 2012
9. [Uveitis, interstitial nephritis and hepatitis with cytomegalovirus in an immunocompetent adult].
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Khaoula Ben A, Hajri S, Barbouch S, Goucha R, Hriz A, Turki S, and Kheder A
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- Adult, Female, Humans, Cytomegalovirus Infections diagnosis, Hepatitis, Viral, Human virology, Immunocompetence, Nephritis, Interstitial virology, Uveitis, Anterior virology
- Published
- 2012
10. [IL1/IL1 Ra, CTLA-4 and Apo1/Fas genes polymorphisms and susceptibility to IgA nephropathy in Tunisian patients].
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Gorgi Y, Sfar I, Goucha R, Aouadi H, Amri M, Makhlouf M, Ben Romdhane T, Cherif M, Jendoubi-Ayed S, Ben Abdallah T, and Ayed K
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- Adult, Aged, Aged, 80 and over, Antigens, CD genetics, CTLA-4 Antigen, Female, Genetic Predisposition to Disease, Humans, Interleukin 1 Receptor Antagonist Protein genetics, Interleukin-1 genetics, Male, Middle Aged, Tunisia, fas Receptor genetics, Glomerulonephritis, IGA genetics, Polymorphism, Single Nucleotide
- Abstract
Background: The IgA nephropathy (IgA-N) is considered the most common form of primary glomerulonephritis and its pathogenic mechanisms are very complex. The study of several genes which encode for immunoregulator molecules in inflammatory and immunological responses during the disease, allowed to describe some number of polymorphisms would be involved in the molecular expression, the road marking, the synthesis and\or the binding to the receptors. So an abnormality of the molecular function associated with its polymorphism would be suggested in the genetic predisposition to the disease., Aim: To determine interleukin 1 (IL1), interleukin1 receptor antagonist (IL1 Ra), CTLA-4 and Apo1/Fas genes polymorphisms frequencies in IgA-N in order to estimate the impact of these polymorphisms in the disease susceptibility., Methods: The polymorphism of a single nucleotide (SNP) at (-889) IL1 a of 21 IgA-N patients and 100 healthy blood donors, as controls, was studied by PCRSSP. The SNPs of the IL1 ß (+3954), CTLA-4 (+49) and l'Apo1/Fas were analyzed by PCR RFLP and finally the polymorphism of the IL1 Ra gene was determined by a PCR VNTR (variable number tandem repeat)., Results: Investigation of IL1a/ß and Apo1/Fas polymorphisms showed no differences in genotypes and alleles frequencies between IgA-N patients and controls. However, genotype AA of CTLA-4 exon1 (+49) was significantly higher in patients (47.62%) than in controls (9.1%) p<0.001. Nevertheless, the clinical, histological and biological characteristics of IgA-N were similar in AA CTLA-4 genotype patients compared to AG or GG genotype patients. We fund also, a significant increased frequency of 1/1 IL1 Ra genotype in IgA-N patients (95.24%) compared to controls (54%) (p<0.001) (p<0.001)., Conclusion: We conclude that the susceptibility to IgA-N seems to be associated with the presence of CTLA-4 AA and IL1 Ra 1/1 genotypes in Tunisian population. However, the lack of association between IL1 a/ß and Apo1/fas genes polymorphisms should be further investigated by large population based studies.
- Published
- 2010
11. [Renal involvement in Behcet's disease].
- Author
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Ounissi M, Ben Abdelghani K, Gargueh T, Turki S, Goucha R, Abderrahim E, Ben Hamida F, Ben Maiz H, and Khedher A
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- Adolescent, Adult, Female, Humans, Male, Middle Aged, Retrospective Studies, Young Adult, Behcet Syndrome complications, Kidney Diseases etiology
- Abstract
Background: Renal involvement in the Behcet's disease is rare. The clinical features vary from urinary sediment's abnormalities to ESRD., Aim: We propose to study the clinical, biological and histological data, the therapeutic management and the prognosis of patients., Methods: We report a retrospective study including 8 patients representing 1.23 % of cases., Results: The average age of the patient was of 37 +/- 12. 35 years with a clear male prevalence. Urinary signs were discovered fortuitously by the strips in the majority of the cases after an average of 18 months. It's about proteinuria and hematuria. Renal insufficiency and hypertension were rare. Pathological study highlighted 3 cases of amyloidosis, 2 cases of IgA nephropathy, 1 case of minimal change disease, 1 case of endo and extracapillary glomerulonephritis and 1 case of interstitial nephropathy. Patients having GN were treated by corticoids and immunosuppressive agents and those having an interstitial nephropathy were treated symptomatically with good evolution in the majority of the cases. Only one patient is dead, he had amyloidosis. Prognosis depended on the precocity of the diagnosis, the histological type and the treatment., Conclusion: The renal involvement during Behçet's disease is rare. Amyloidosis and Ig A nephropathy are the most frequent. Treatment is still controversial.
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- 2010
12. [Peritoneal dialysis in the elderly].
- Author
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Ounissi M, Ben Abdallah T, Abderrahim E, Ben Hamida F, Goucha R, Ben Maiz H, and Kheder A
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- Aged, Cardiovascular Diseases complications, Female, Humans, Male, Retrospective Studies, Kidney Failure, Chronic therapy, Peritoneal Dialysis adverse effects
- Abstract
Background: Peritoneal dialysis is used more and more as treatment of substitution of the end stage renal disease at the old subjects of more than 65 years and its effectiveness and its good tolerance were shown., Aims: To study the epidemiological and clinical profile of these patients, the indication and the advantages of PD, the various complications, the elements of prognostic and the survival of the patients and the technique., Methods: We made a retrospective study including a series of 13 old patients of more than 65 years and treaties by PD during the period extending from the 1983/2/11 to the 2005/12/31. They are 10 men and 3 women on average of 70 +/- 3.1 year and representing 3.62% of the totality of the patients. The diabetic and vascular nephropathies represent the first cause of ESRD., Results: The PD was used of first intention at 53.84% of the patients whose majority suffers from a malnutrition due to advanced age, anorexia, psychological disorders, bad dental state and uraemia. The cardiovascular complications are frequent in this age bracket explaining heavy morbidity. The pulmonary and urinary infectious complications are also frequent. The more frequent peritonitis compared to the literature, are comparable between the 2 age brackets < and = with 65 years and the mode of PD (APD or CAPD). The time separating the beginning from PD and which has occurred of the peritonitis is shorter in APD. The lesions of renal osteodystrophy are found among 6 patients: 3 cases of hyperparathyroidism and 3 cases of adynamic osteopathy. The return in HD is rare due to dysfunction of the catheter. The survival of the patients is 92.8% at 1 year and 60.8% at 5 years; that of the technique is worse with 88.3% at 1 year and 33.7% at 5 years Eight patients died (61.5%) because of cardiovascular diseases and of the infections. We found a correlation statistically significant between the survival of the patients and the mode of PD, on the other hand any correlation was not found with the age or the sex. The survival of the technique is not correlated to a significant degree with the age, the sex and the mode of PD., Conclusion: Peritoneal dialysis is used of first intention at more half of the old subjects and remains a last recourse for haemodialysis which have an initially vascular problem. The family support and the good nurse allow these patients to adhere well to the technique. The cardiovascular diseases and the infections are responsible for heavy morbi-mortality. The survival of the technique is worse than that of the patients.
- Published
- 2009
13. [Renal involvement in Fabry disease].
- Author
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Kaaroud H, Béji S, Boubaker K, Ben Moussa F, Ben Hamida F, Goucha R, Ben Dridi MF, Ben Turkia H, and Kheder A
- Subjects
- Humans, Male, Middle Aged, Renal Insufficiency etiology, Fabry Disease diagnosis, Glomerulosclerosis, Focal Segmental etiology
- Abstract
Background: Fabry disease is an X-linked recessive lysosomial storage disorder that is caused by deficient activity of alpha galactosidase A. Renal involvement occurs generally in hemizygous forms., Aim: We report one case of renal involvement in Fabry disease., Case Report: A 47 year-old-man had focal and segmental glomerulosclerosis with moderate renal failure. As the patient presented history of acroparesthesias, hearing loss, left ventricular hypertrophy with arrhythmia and corneal deposits, hemizygous Fabry disease was suspected. This diagnosis was confirmed with low alpha galactosidase activity. After a follow up of 5 years, the renal function remains stable but the patient died by cardiac arrhythmia., Conclusion: Occurrence of a glomerulonephritis associated with an hypertrophic cardiopathy without hypertension should advocate Fabry disease.
- Published
- 2007
14. [Membranoproliferative glomerulonephritis in patients with cryoglobulinemia complicating hepatitis C virus: report of 11 cases].
- Author
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Ben Fatma L, Ben Hamida F, Aoudia R, Goucha R, Kaaroud H, Béji S, Barbouch S, Hedri H, Abderrahim E, Elyounsi F, Ben Abdallah T, Ben Moussa F, and Kheder A
- Subjects
- Adult, Aged, Biopsy, Fine-Needle, Female, Humans, Kidney pathology, Liver pathology, Male, Middle Aged, Retrospective Studies, Cryoglobulinemia complications, Glomerulonephritis, Membranoproliferative complications, Hepatitis C, Chronic complications
- Abstract
Background: Membranoproliferative glomerulonephritis in patients with cryoglobulinemia complicating hepatitis C virus have yet been reported. Although, it remains controversial, antiviral treatment seems to be able to improve the outcome of glomerulonephritis., Aim: The objectives of the study were to analyze characteristics of this association and to report literature data and newness treatment., Methods: It's a retrospective study including 11 patients with membranoproliferative glomerulonephritis, hepatitis C virus and mixed cryoglobulinemia. Hepatitis C virus antibodies was identified by ELISA technique. Hepatitis C virus genotype was identified in one patient. Cryoglobulins were isolated from sera of all patients at 37 degrees Celsius., Results: Patients were 3 men and 8 women with a mean age of 51.9 +/- 15.5 years. Between the 11 patients, 7 had hypertension, 9 had nephrotic syndrome and 10 had chronic renal failure. Renal biopsy showed membranoproliferative glomerulonephritis lesions in all cases with fibrinoid thrombi in 8 cases. Six patients had chronic liver disease. Liver biopsy was performed in 4 patients, showing histological feature compatible with chronic active hepatitis in 2 cases. No patient had antiviral therapy. Renal failure was stable in 5 cases and progressed in 6 cases with end stage renal failure in 3 of them. One patient died, 4 months after diagnosis, because of severe pulmonary involvement in cryoglobulinemic vasculitis. In literature, treatment is dominated by antiviral therapy composed first by Interferon Alpha alone. Combination therapy associating Interferon and Ribavirin was recently used in renal involvement; it is clearly more effective than interferon alpha alone., Conclusion: Hepatitis C virus detection should be performed when membranoproliferative glomerulonephritis is associated with cryoglobulinemia. Antiviral treatment should be more widely used in Tunisia to evaluate his effect on renal involvement
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- 2007
15. [Myeloma, Kaposi's sarcoma and HHV8 infection in hemodialyzed patient].
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Bacha MM, Goucha R, Zouaghi K, Jebali H, Fazaa B, Hedri H, El Younsi F, Abderrahim E, Ben Hamida F, Ben Abdallah T, Ben Moussa F, Kammoun R, Ben Maiz H, and Kheder A
- Subjects
- Aged, 80 and over, Humans, Kidney Failure, Chronic complications, Kidney Failure, Chronic therapy, Male, Sarcoma, Kaposi virology, Skin Neoplasms virology, Herpesvirus 8, Human isolation & purification, Multiple Myeloma complications, Renal Dialysis, Sarcoma, Kaposi complications, Skin Neoplasms complications
- Abstract
Background: The association between Kaposi's sarcoma, Human Herpes Virus 8 infection and multiple myeloma is still controversial especially in hemodialysed patient., Aim: report a new case of this association., Observation: We report the case of a 83 year old man in whom the diagnosis of multiple myeloma of IgA/kappa had been made in December 2003 with end stage renal failure requiring hemodialysis. Initially, it had been treated with Melphalan, Cyclophosphamide, Prednisolone and Vincristine and secondary by Melphalan and Prednisone. Three months later, he had developed extensive porpour lesions in his lower limbs. Skin biopsy had been informed of Kaposi's sarcoma. Human Herpes Virus 8 test was positive., Conclusion: Our observation is another case supporting the hypothesis that Kaposi's sarcoma and multiple myeloma share a common aetiology such as Human Herpes Virus 8. The immunodepressed state related to aging, multiple myeloma, chemotherapy and hemodialysis was the probable factor responsible of rapidly progressive Kaposi's sarcoma in our patient. The association myeloma and Human Herpes Virus 8 infection is still controversial.
- Published
- 2007
16. [Complications of distal tubular acidosis in primary Sjögren's syndrome].
- Author
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Béji S, Kaaroud H, Ben Moussa F, Raies L, Jebali H, Ben Hamida F, Goucha R, El Younsi F, Ben Abdallah T, Ben Maiz H, and Kheder A
- Subjects
- Adult, Female, Humans, Hypokalemia etiology, Middle Aged, Nephrocalcinosis etiology, Osteomalacia etiology, Acidosis, Renal Tubular etiology, Sjogren's Syndrome complications
- Abstract
Renal involvement in primary Sjögren's syndrome occurs in 10-60% of cases. Tubulointerstitial nephritis with distal renal tubular acidosis (DRTA) is the main type of involvement. It's generally asymptomatic and revealed by complications of DRTA. We report 4 cases of GJS complicated by nephrocalcinosis, tetapresic hypokaliemia and osteomalacia. In 2 cases, nephrocalcinosis was diagnosed simultaneously with the GJS. The 2 other cases were diagnosed 3 and 15 years after primary GJS. All patients were treated by coticosteroids at the dose of 0.5 mg/Kg/jour, alkaline solution, K Cl in 2 cases and vitamin D in 2 cases. After a mean follow up of 8.7 years, the renal function remain stable in the 3 cases of nephrocalcinosis and in a patient with osteomalacia, bone lesions progressed. In conclusion, DRTA must be detected by acidification tests in patients with primary Sjögren's syndrome because of their latency and to prevent severe complications.
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- 2007
17. [A case of preserved fertility in an hemodialyzed patient with systemic lupus erythematosus].
- Author
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Béji S, Kaaroud H, Ben Moussa F, Ben Hamida F, Goucha R, Abderrahim E, El Younsi F, Ben Abdallah T, Ben Maiz H, and Kheder A
- Subjects
- Adult, Female, Humans, Kidney Failure, Chronic etiology, Pregnancy, Pregnancy Outcome, Fertility, Kidney Failure, Chronic therapy, Lupus Erythematosus, Systemic complications, Pregnancy Complications therapy, Renal Dialysis
- Abstract
Background: Pregnancy and child birth in haemodialysis remains a rare event, even more, when pregnancy occurs in patient with systemic lupus erythematosus (SLE)., Aim: We report a case of a patient with end stage renal failure secondary to SLE and who carried out 3 pregnancies., Case Report: She was a woman with proliferative and diffuse lupus glomerulonephritis since 1985 treated by corticosteroids and cyclophosphamide. In 1995, she developed chronic renal failure. In 1996, she underwent a 1st full term spontaneous pregnancy with normal birth weight. In 2001, she underwent a second spontaneous pregnancy while she was on periodic haemodialysis. She had a full term baby birth with a birth weight at 1 Kg 700 and who died 4 days later. In 2002, she had a third pregnancy with voluntary abortion at 8 weeks., Conclusion: Our patient had conserved fertility despite treatment by cyclophosphamide, chronic renal failure and haemodialysis. The two successful deliveries may be attributed to the control of SLE activity and to the adequacy of haemodialysis.
- Published
- 2007
18. [Epidemiology of glomerular diseases in Tunisia from 1975 to 2005. Influence of changes in healthcare and society].
- Author
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Ben Maïz H, Abderrahim E, Ben Moussa F, Goucha R, and Karoui C
- Subjects
- Adult, Aged, Child, Delivery of Health Care, Female, Glomerulonephritis complications, Health Status, Humans, Male, Socioeconomic Factors, Time Factors, Tunisia epidemiology, Glomerulonephritis epidemiology
- Abstract
Between April 1975 and March 2005, 4,436 cases of histologically proven glomerulonephritis (GN) were diagnosed by the same team at the Kidney Unit of Charles Nicolle Hospital in Tunis. Respectively 1,510, 1,419 and 1,509 cases were diagnosed in 1975-1985, 1985-1995, and 1995-2005. We compared trends in the incidence rates of the different types of GN and those of Tunisian indicators of health, social and economic status. The following differences were found between 1975-1985 and 1995-2005:--As a proportion of all cases of GN, the frequency of amyloidosis fell from 12,6 % to 6,5 % (p < 0,0001). The 444 cases of amyloidosis observed during the study period were of type AA in 87 % of cases, and were related to chronic infectious diseases in 239 cases (54 %; pulmonary tuberculosis in 114 cases). The frequency of tuberculosis-associated amyloidosis fell during the study period, in parallel with the reduction in the incidence of tuberculosis in the Tunisian population (48,7 cases/100,000 inhabitants in 1983 to 20,17 in 2004). Lupus nephritis accounted for 7.7 % of all cases of GN diagnosed in 1975-1985, compared to 13 % in 1995-2005 (p < 0,00001). Increased exposure to sunlight and use of cosmetics could be involved in this increase.--The incidence of both proliferative endocapillary and membranoproliferative GN (as a proportion of all cases of GN) fell between 1975-1985 and 1995-2005, from 15,9 % and 21,6 % to 6,9 % and 7,7 %, respectively (p < 0,0001). This matched a drop in the incidence of acute rheumatic fever in the Tunisian population, from 7,26/100,000 inhabitants in 1984 to 0,83 in 2004, probably as a result of public health measures and widespread use of antibiotics. The incidence of membranous GN increased from 11,1 to 17,7 % in adults (p < 0,001) whereas it fell from 10,1 to 4,6 % in children (p < 0,01), possibly as a result of a nationwide HBV vaccination program launched in 1995. The incidence of IgA nephropathy increased from 0,9 to 12,9 % in adults (p < 0,0001) and from 0,3 % to 18,4 % in children, but remained relatively stable in elderly adults. This study, conducted in a single center, by the same team, and using the same renal biopsy practices, confirms that the control of infectious diseases in Tunisia has led to a substantial regression of proliferative endocapillary and membranoproliferative GN and renal amyloidosis. Environmental factors, such as the adoption of western lifestyles, could explain the increase in lupus and IgA nephropathies.
- Published
- 2006
19. [Renal amyloidosis complicating the outcome of chronic inflammatory colitis].
- Author
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Béji S, Kaaroud H, Ben Moussa F, Goucha R, Abderrahim E, El Younsi F, and Ben Maïz H
- Subjects
- Adrenal Cortex Hormones therapeutic use, Adult, Amyloidosis drug therapy, Amyloidosis pathology, Colchicine therapeutic use, Female, Gout Suppressants therapeutic use, Humans, Male, Middle Aged, Prognosis, Amyloidosis etiology, Colitis, Ulcerative complications, Crohn Disease complications
- Abstract
Introduction: In 4 patients we observed the association of an amyloid nephropathy and a chronic inflammatory bowel disease (Crohn's' disease in 3 cases and ulcerative rectocolitis in 1 case)., Observations: These patients, aged a mean of 37 years (range: 28-48 years), had been admitted for exploration of a nephrotic syndrome associated with renal failure in 2 cases. The investigations lead to the diagnosis of AA type amyloidosis in the 4 cases. One patient was lost from follow-up. One patient was treated with salazopyrine, one with corticosteroids and one with colchicine. After a mean follow-up of 16 months (5-30 months), all the patients had persistent nephrotic syndrome, with end stage renal failure in one case, persistence of normal renal function in one case and improved renal function in one case. None of the patients exhibited remission in the nephrotic syndrome. The response of amyloidosis to the treatment of the chronic inflammatory bowel disease varied. Corticosteroids and colchicine stabilised renal function in 2 of our patients but without remission in the nephrotic syndrome., Discussion: AA amyloidosis is a rare complication of inflammatory bowel disease. The indication for colchicine is important to consider particularly since the response of amyloidosis to the treatment of the causal disease does not, in the majority of cases, lead to the remission of the amyloidosis, the prognosis of which is determined by the extent of renal involvement.
- Published
- 2004
- Full Text
- View/download PDF
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