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More than 99.9 % of the sequence is identical when comparing the DNA from two individuals. The remaining 0.1 % is responsible, along with other factors such as the environment, for the risk level of developing complex diseases (such as asthma, diabetes or cancer) or for the different pharmacological response to drugs. Despite the incredible advances in genomics in the past few years, identifying the variants involved remains difficult because of the prodigious amount of information to process. The recent completion of the Haplotype Map of the human genome has raised great hopes in the field as it is expected to help reduce the complexity of association studies and thus accelerate the discovery of genes associated with complex diseases. This review details the rationale behind the HapMap project, gives a summary of the results and also describes potential applications of the Haplotype Map.

The goal of this study is to investigate whether social support may constitute a protective factor for attempted suicide among men and, if so, to identify the most important sources and forms of support. The study compares two groups of men who experienced comparable stressful events during the last 12 months : 40 men admitted to hospital emergency following suicide attempts, and 40 men with no history of suicide attempts. Results indicate that the men who attempted suicide perceive less support available and are less satisfied with the support they received following the most difficult stressful event that occurred in the last year. Concrete help and reassurance of worth are the forms of support that appear to be of most importance. This study highlights the importance of social support in the prevention of suicidal behaviours among men.