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4 results on '"DuPont CL"'

3. [Uricolytic therapy. Value of urate oxidase in the treatment of hyperuricemias].

Author

Potaux L, Aparicio M, Maurel C, Ruedas ME, and Martin-Dupont Cl

Subjects
Acute Kidney Injury complications, Adult, Aged, Allantoin biosynthesis, Allantoin blood, Chemical Phenomena, Chemistry, Clinical Trials as Topic, Female, Humans, Kidney Failure, Chronic complications, Male, Metabolic Diseases complications, Metabolic Diseases drug therapy, Middle Aged, Purines metabolism, Urate Oxidase metabolism, Uric Acid metabolism, Gout drug therapy, Urate Oxidase therapeutic use, Uric Acid blood
Abstract

In addition to uricosuric agents and purine synthesis inhibitors, Urate Oxydase may be used in the treatment of hyperuricaemia. This substance breaks down uric acid to allantoin which is soluble and easily excreted. Use of the medication in 14 cases of major gout with tophi and 9 cases of hyperuricaemia secondary to renal insufficiency showed the good tolerance of the substance and it's clinical and biological effectiveness.

Published
1975

4. [Diabetes and pregnancy].

Author

MAHON R, MARTIN-DUPONT CL, and BOTTON C

Subjects
Female, Humans, Pregnancy, Diabetes Mellitus
Published
1959

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