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The diagnosis of ductal carcinoma in situ (DCIS) using core biopsy (CB) does not ensure the absence of invasion on final excision. The risk of invasion and upstaging ranges from 8% to 42.7% in various studies. The role of sentinel lymph node biopsy in patients on CB of DCIS has been the subject of debate. Furthermore, SLN is not usually required in all cases of DCIS but may be indicated in such specific cases: 1) where mastectomy is performed; 2) with large lesions or palpable mass; 3) with high grade tumours; 4) and where the pathologist cannot rule out micro-invasion. Pure DCIS patients do have tumour positive findings, but a majority of these are isolated tumour cells (ITCs) or micro-metastases. SLN positive does not affect the outcomes of DCIS patients. [ABSTRACT FROM AUTHOR]

Abstract: Diabetic mastopathy is an uncommon benign entity occurring in young women with type 1 diabetes. Its clinical and radiological signs are not specific and often mimic a breast carcinoma. However, the benign nature of this lesion is easily recognized on histological examination, visualizing dense keloid-like fibrosis, lymphocytic lobulitis and ductitis with lymphocytic perivascular inflammation, with or without epithelioid-like fibroblasts. Surgery can generally be avoided. The evolution of this entity is characterized by the risk of local growth, bilateralisation or recurrence after surgical treatment. We present a case in which the core biopsy allowed the diagnosis of a diabetic mastopathy and we discuss its clinical, diagnostic, pathological and therapeutic particularities. [ABSTRACT FROM AUTHOR]

Abstract: Objectives: Clinical and pathological features of mucocele-like lesions in the breast are well-known though rare. The aim of this study is to evaluate the frequency of other breast proliferations association, the underestimation with ultrasound guided core biopsy or stereotactic vacuum-assisted biopsy and its implication on patient''s management. Patients and methods: Retrospective study conducted in the gynecology departments of Tours and Orleans between January 1997 and December 2007, reviewing the records of all patients with diagnosis of mammary mucocele-like lesion on core or stereotactic biopsy. Results: Eight cases were identified, all screen-detected (mammographic abnormalities) on asymptomatic women. For the five cases diagnosed by core biopsy, initial histological examination found isolated mucocele-like lesions in four cases, and association with atypical ductal hyperplasia in the other case. Vacuum-assisted biopsy and/or surgical excision were always done finding an association with mucinous carcinoma and another case of association with atypical ductal hyperplasia. For cases diagnosed by vacuum-assisted biopsy, histological examination was almost similar to the surgical one. Discussion and conclusion: High rate of associated lesions (especially atypical ductal hyperplasia) makes necessary the advice of complementary surgical excision after a diagnosis of a mucocele-like lesion on a biopsy specimen. Vacuum-assisted biopsies could have their place as a curative method in certain conditions. [Copyright &y& Elsevier]