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2 results on '"Clain, E"'

1. [Cytotoxicity of aurintricarboxylic acid: inhibition of cell proliferation and of protein synthesis in Allium sativum L. root meristems].

Author

Levy F, Brulfert A, Clain E, Tirmarche D, Deysson G, and Truhaut R

Subjects
Cell Division drug effects, Mitosis drug effects, Plants metabolism, Aurintricarboxylic Acid pharmacology, Cyclohexanecarboxylic Acids pharmacology, Plant Proteins biosynthesis, Plants drug effects
Abstract

The inhibitory action of aurine-tricarboxylic acid (ATA) on protein synthesis, known in vitro, has been checked in vivo in Allium sativum L. root meristems. Parallel to this inhibition, ATA acts on cell proliferation, on the one hand by preventing the entering of cells into prophase and, on the other hand, by disturbing the process of mitosis.

Published
1975

2. [Cytotoxicity of cadmium : study on root meristems of Allium sativum L].

Author

Clain E and Deysson G

Subjects
Dose-Response Relationship, Drug, Mitotic Index, Cadmium toxicity, Cell Division drug effects, Garlic drug effects, Plants, Medicinal
Abstract

Cadmium nitrate, acetate and sulphate cause death of root meristems of Allium sativum at 5.10(-7) Mol/ml concentration for the two first ones and 10(-7) Mol/ml for the last one. Lower concentrations do not induce chromosomal aberrations. As to the cellular toxicity, cadmium salts are between phenyl-mercuric-hydroxid and lead nitrate, the first one being the most active.

Published
1976

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