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Your search keyword '"Carraro V"' showing total 3 results
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3 results on '"Carraro V"'

1. [Tuning transgene expression with an artificial diet: a compelling resource in gene therapy].

Author

Bruhat A, Chaveroux C, Carraro V, Jousse C, Averous J, Maurin AC, Parry L, Mesclon F, Muranishi Y, Baril P, Do Thi A, Ravassard P, Mallet J, and Fafournoux P

Subjects
Adult, Amino Acids, Essential pharmacology, Animals, Cell Cycle Proteins genetics, Chickens, Gene Expression Regulation drug effects, Humans, Mice, Protein Serine-Threonine Kinases antagonists & inhibitors, Protein Serine-Threonine Kinases genetics, Rats, Repressor Proteins genetics, Swine, Thymidine Kinase genetics, Transcriptional Activation drug effects, Amino Acids, Essential deficiency, Food, Formulated, Genetic Therapy methods, Response Elements drug effects, Transgenes drug effects, Transgenes genetics
Published
2017
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3. [Adaptation to the availability of essential amino-acids: role of GCN2/eIF2α/ATF4 pathway].

Author

Fafournoux P, Averous J, Bruhat A, Carraro V, Jousse C, Maurin AC, Mesclon F, and Parry L

Subjects
Amino Acids, Amino Acids, Essential deficiency, Animals, Eukaryotic Initiation Factor-2 metabolism, Homeostasis, Humans, Immunity, Malnutrition, Neuronal Plasticity, Nutritional Status, Phosphorylation, Signal Transduction physiology, Adaptation, Biological physiology, Amino Acids, Essential administration & dosage, Diet, Protein Serine-Threonine Kinases physiology
Abstract

In mammals, metabolic adaptations are required to overcome nutritional deprivation in amino-acids/proteins as well as episodes of malnutrition. GCN2 protein kinase, which phosphorylates the α subunit of the translation initiation factor eIF2, is a sensor of amino-acid(s) deficiencies. On one hand, this review briefly describes the main features of amino-acid metabolism. On the other hand, it describes the role of GCN2 in regulating numerous physiological functions., (© Société de Biologie, 2016.)

Published
2015
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