1. [Malignant transformation of odontogenic cysts]
- Author
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G C, Timoşca, C, Cotuţiu, and L, Gavriliţà
- Subjects
Adult ,Male ,Maxillary Neoplasms ,Radicular Cyst ,Epidermal Cyst ,Middle Aged ,Epithelium ,Maxillary Diseases ,Mandibular Neoplasms ,Cell Transformation, Neoplastic ,Odontogenic Cysts ,Carcinoma, Squamous Cell ,Humans ,Keratins ,Female ,Mandibular Diseases ,Aged - Abstract
Five out of 4,172 operated maxillary cysts (3 developed within the maxillary and 2 in the mandible) presented a malignant change of epithelium. In all these 5 cases histology demonstrated a transition from normal to cancerous epithelium. The overall percentage of malignant change was of 0.12%, with 0.077% for non-keratinized epithelium lining odontogenic cysts (3 cases) and 0.65%, that is 8 times higher, for keratinized ones (2 cases). Keratinization of cystic epithelium and chronic inflammatory lesions were the main risk factors.
- Published
- 1995