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4 results on '"C, Chapelin"'

1. [Evaluation of the brushing technique in nasal cytology]

Author

L, Gilain, C, Chapelin, M, Boucherat, R, Peynegre, and E, Escudier

Subjects
Adult, Nasal Mucosa, Evaluation Studies as Topic, Cytological Techniques, Humans, Cell Count
Abstract

Analysis of nasal cytology provides useful information for the diagnosis of rhinitis. This analysis represents an interesting tool for objective assessment of nasal pathology. The purpose of this study was to describe the brushing method for obtaining nasal cytologic specimen. Samples were carried out from nine adult patients with chronic nasal obstruction. In all cases, the cytologic specimen had a good amount of well-preserved cells, easy to identify on morphological criteria. A differential cell count was performed on the different epithelial cell types present in the specimen and the results are reported in the present study. In conclusion, brushing method is non invasive and allows to precisely evaluate both epithelial and inflammatory cells present in the nasal mucosa.

Published
1994

2. [Brush technique in cytological analysis of the nasal mucosa. A critical and comparative analysis]

Author

L, Gilain, E, Escudier, C, Chapelin, M, Boucherat, V, Faulcon, and R, Peynègre

Subjects
Adult, Inflammation, Microscopy, Nasal Mucosa, Adolescent, Biopsy, Child, Preschool, Cytodiagnosis, Humans, Epithelial Cells, Child
Abstract

The cytological study of the nasal mucosa is one the essential steps toward a better understanding of the physicopathological mechanisms involved in chronic affections of the nose. The development of a reliable, reproducible noninvasive technique to obtain cells in the prerequisite for this analysis. The brush technique is based on the use of a small cylindric nylon brush which is rotated as it is moved back and forth across the nasal mucosa to harvest the various cell types present on the surface of the mucosa. The specimen obtained is centrifuged and examined under an optical microscope. A semi-quantitative analysis is carried out to determine the relative richness of the specimen in epithelial cells (ciliated, qoblet and basal cells) and in inflammatory cells (neutrophils, basophils, eosinophils, lymphocytes, and monocytes). A precise differential cell count is then performed. According to the results obtained, an immunologic marker study of lymphocyte subsets may also be done using the same specimen. This technique may be used in both children and adults and permits cell harvest from various sites within the nasal fossa. Already tested in the study of the activity of cilia, this method is promising for the cytological study of the nasal mucosa. The brush method and other techniques of cell harvest are described and compared.

Published
1992

3. [Evaluation of the brushing technique in nasal cytology].

Author

Gilain L, Chapelin C, Boucherat M, Peynegre R, and Escudier E

Subjects
Adult, Cell Count, Evaluation Studies as Topic, Humans, Cytological Techniques, Nasal Mucosa pathology
Abstract

Analysis of nasal cytology provides useful information for the diagnosis of rhinitis. This analysis represents an interesting tool for objective assessment of nasal pathology. The purpose of this study was to describe the brushing method for obtaining nasal cytologic specimen. Samples were carried out from nine adult patients with chronic nasal obstruction. In all cases, the cytologic specimen had a good amount of well-preserved cells, easy to identify on morphological criteria. A differential cell count was performed on the different epithelial cell types present in the specimen and the results are reported in the present study. In conclusion, brushing method is non invasive and allows to precisely evaluate both epithelial and inflammatory cells present in the nasal mucosa.

Published
1994

4. [Brush technique in cytological analysis of the nasal mucosa. A critical and comparative analysis].

Author

Gilain L, Escudier E, Chapelin C, Boucherat M, Faulcon V, and Peynègre R

Subjects
Adolescent, Adult, Biopsy, Child, Child, Preschool, Epithelial Cells, Humans, Inflammation pathology, Microscopy, Nasal Mucosa pathology, Cytodiagnosis methods, Nasal Mucosa cytology
Abstract

The cytological study of the nasal mucosa is one the essential steps toward a better understanding of the physicopathological mechanisms involved in chronic affections of the nose. The development of a reliable, reproducible noninvasive technique to obtain cells in the prerequisite for this analysis. The brush technique is based on the use of a small cylindric nylon brush which is rotated as it is moved back and forth across the nasal mucosa to harvest the various cell types present on the surface of the mucosa. The specimen obtained is centrifuged and examined under an optical microscope. A semi-quantitative analysis is carried out to determine the relative richness of the specimen in epithelial cells (ciliated, qoblet and basal cells) and in inflammatory cells (neutrophils, basophils, eosinophils, lymphocytes, and monocytes). A precise differential cell count is then performed. According to the results obtained, an immunologic marker study of lymphocyte subsets may also be done using the same specimen. This technique may be used in both children and adults and permits cell harvest from various sites within the nasal fossa. Already tested in the study of the activity of cilia, this method is promising for the cytological study of the nasal mucosa. The brush method and other techniques of cell harvest are described and compared.

Published
1992

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