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The classical triad of acute rheumatic fever (ARF) occurrence includes the presence of a rheumatoid group A streptococcal strain, a genetically susceptible host, and an aberrant immune response of the host. No vaccine against Streptococcus pyogenes is available to date; however, in the South Pacific region, CANVAS continues active research to develop an optimal vaccine against streptococcal infections and their complications. In French Polynesia (Pf), an area where ARF remains endemic, a local program has been set up in 1983 and reinforced in 2013, to fight this disease. This thesis proposes an overview of the Pf pharmacists knowledge about the ARF. A questionnaire established shed light on the lack of accurate information on ARF among the community of pharmacists in Pf. Their marginal intervention was also noted in the secondary prevention program for ARF patients. Yet, an interdisciplinary approach through the active involvement of all the professionals of health and care would better control the evolution of this disease., La triade classique de survenue du rhumatisme articulaire aigu (RAA) comprend la présence d’une souche streptococcique du groupe A rhumatogène, d’un hôte génétiquement sensible et d’une réponse immunitaire aberrante de l'hôte. Aucun vaccin contre Streptococcus pyogenes n’est disponible à ce jour ; toutefois, dans la région du Pacifique Sud, le CANVAS continue les recherches actives pour permettre le développement d’un vaccin optimal contre les infections streptococciques et leurs complications. En Polynésie française, une zone où le RAA reste endémique, un programme local de lutte contre cette maladie a été mis en place depuis 1983 et renforcé en 2013. Cette thèse a permis de visualiser les connaissances des pharmaciens d’officine de Polynésie française sur le RAA et son ampleur. Le questionnaire d’enquête préliminaire a permis de mettre en lumière le manque d’informations précises des pharmaciens d’officine sur le RAA. On a également pu remarquer leur intervention marginale dans le programme de prévention secondaire des patients atteints de RAA. Pourtant une approche interdisciplinaire via l’implication active de tous les professionnels permettrait davantage de contrôler l’évolution de cette maladie.

Introduction: comprehensive support at birth in technical facilities is an alternative little known to women, few studies have been published on the subject and the opening of technical platforms remains restricted. Yet women aspire to a different care with in particular as main expectations: listening and accompaniment. We therefore carried out a study with precise objectives on the adverse outcomes and the influence of medical work. Material and method: this is a retrospective, multicentric study carried out on file and including 668 women who gave birth in four different technical platforms of the Groupe Naissances between January 1, 2012 and December 31, 2014. Results: within the Groupe Naissances, women give birth mainly by spontaneous low (69.5%) and 48.5% without analgesia. 6% of women have episiotomy or complicated tears, and 1.5% postpartum haemorrhage. Newborns were well adapted to ectopic life and 1.4% were transferred. The rate of haemorrhage was significantly lower than the general population (p