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2. [HTLV-I retroviral variant in Zaire in patient with chronic neuromyelopathy. Nucleotidic sequence of the envelope gene].

Author

Gessain A, Boeri E, Kazadi K, Garin B, Salaün JJ, Gallo R, de Thé G, and Franchini G

Subjects
Base Sequence, Chronic Disease, Democratic Republic of the Congo, Genetic Variation genetics, Humans, Male, Middle Aged, Genes, env genetics, Human T-lymphotropic virus 1 genetics, Paraparesis, Tropical Spastic microbiology
Abstract

The oncoretrovirus HTLV-I is the etiological agent of adult T cell leukemia (ATL) and tropical spastic paraparesis/HLTV-I associated myelopathy (TSP/HAM). In contrast to the human lentiretroviruses, HIV-I and HIV-2, the causative agents of AIDS, HTLV-I is genetically very stable. We report here the molecular characterization of the envelope gene of an HTLV-I variant present in a TSP/HAM patient from Zaïre, raising the question of its relevance to disease or the ethnic and/or geographical origin of the patient.

Published
1992

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