1. [Side effects of chemotherapy for testicular cancers and post-cancer follow-up].
- Author
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Joly F, Ahmed-Lecheheb D, Thiery-Vuillemin A, Orillard E, and Coquan E
- Subjects
- Cardiovascular Diseases chemically induced, Cognition drug effects, Cognition Disorders chemically induced, Fatigue Syndrome, Chronic chemically induced, Fertility drug effects, Follow-Up Studies, Humans, Infertility, Male chemically induced, Infertility, Male prevention & control, Lung Diseases chemically induced, Male, Metabolic Syndrome chemically induced, Neoplasms, Second Primary chemically induced, Nervous System Diseases chemically induced, Testicular Neoplasms psychology, Time Factors, Antineoplastic Agents adverse effects, Testicular Neoplasms drug therapy
- Abstract
Testicular cancers are the most frequent and the most curable cancers in young men. Treatments of these cancers represent a great success with cure rate over to 95 %. However, chemotherapy side effects may occur during or after several years post-treatment. This review aimed to highlight complications and physical and psychological side effects occurring mainly after chemotherapy treatment for testicular cancer, and to propose a personalized post-cancer plan specific for patients treated for testicular cancer. Treatments of these cancers can cause short-term complications (asthenia, nausea, vomiting, alopecia..). These side effects disappear within a few months after the end of the treatments. Late complications may occur several years post-treatment. Cardiovascular disease, metabolic syndrome and secondary neoplasia represent the most severe late effects among patients treated for testicular cancer. Given the increased incidence of these chemotherapy-induced side effects, it is indispensable to establish a specific follow up which must include a particular vigilance on the risk of occurrence of second cancer, a follow-up of the cardio-vascular risk factors, pulmonary and auditory follow-up, and early detection of psychosocial disorders., (Copyright © 2019. Published by Elsevier Masson SAS.)
- Published
- 2019
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